Search Count: 18
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Structure Of P110 Alpha Bound To (S)-1-(4-((2-(4-(4-(2-Amino-4-(Difluoromethyl)Pyrimidin-5-Yl)-6-(3-Methylmorpholino)-1,3,5- Triazin-2-Yl)Piperazin-1-Yl)-2-Oxoethoxy)Methyl)Piperidin-1-Yl)Prop-2-En-1-One (Compound 9)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.67 Å Release Date: 2024-08-28 Classification: TRANSFERASE/Inhibitor Ligands: RNX |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-08-28
Ligands: RNX
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Structure Of Pik3Ca With Covalent Inhibitor 19
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.69 Å Release Date: 2022-04-06 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 2Q7 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-04-06
Ligands: 2Q7
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Structure Of Pik3Ca With Covalent Inhibitor 22
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.85 Å Release Date: 2022-04-06 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 2IX |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-04-06
Ligands: 2IX
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Gedatolisib Bound To The Pi3Kg Catalytic Subunit P110 Gamma
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.55 Å Release Date: 2021-03-17 Classification: TRANSFERASE Ligands: VL1 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-03-17
Ligands: VL1
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Ipi-549 Bound To The Pi3Kg Catalytic Subunit P110 Gamma
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.65 Å Release Date: 2021-03-17 Classification: TRANSFERASE/TRANSFERASE Inhibitor Ligands: V7Y |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-03-17
Ligands: V7Y
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Nvs-Pi3-4 Bound To The Pi3Kg Catalytic Subunit P110 Gamma
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.15 Å Release Date: 2021-03-17 Classification: TRANSFERASE/TRANSFERASE Inhibitor Ligands: VLV |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-03-17
Ligands: VLV
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Pqr530 [(S)-4-(Difluoromethyl)-5-(4-(3-Methylmorpholino)-6-Morpholino-1,3,5-Triazin-2-Yl)Pyridin-2-Amine] Bound To The Pi3Ka Catalytic Subunit P110Alpha
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.15 Å Release Date: 2019-06-26 Classification: TRANSFERASE Ligands: M1J |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-06-26
Ligands: M1J
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Mpi3Kd In Complex With Az3
Organism: Mus musculus
Method: X-RAY DIFFRACTION Resolution:2.55 Å Release Date: 2019-02-06 Classification: TRANSFERASE Ligands: FGE |
Organism: Mus musculus
Method: X-RAY DIFFRACTION
Release Date: 2019-02-06
Ligands: FGE
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Pqr309 - A Potent, Brain-Penetrant, Orally Bioavailable, Pan-Class I Pi3K/Mtor Inhibitor As Clinical Candidate In Oncology
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.70 Å Release Date: 2017-09-06 Classification: TRANSFERASE Ligands: A3W, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-09-06
Ligands: A3W, SO4
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Tubulin Mtd265-R1 Complex
Organism: Rattus norvegicus, Gallus gallus, Bos taurus
Method: X-RAY DIFFRACTION Resolution:2.25 Å Release Date: 2017-03-22 Classification: CELL CYCLE Ligands: GTP, MG, CA, GOL, UGI, GDP, MES, ACP |
Organism: Rattus norvegicus, Gallus gallus, Bos taurus
Method: X-RAY DIFFRACTION
Release Date: 2017-03-22
Ligands: GTP, MG, CA, GOL, UGI, GDP, MES, ACP
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Structure Of Phosphoinositide 3-Kinase Gamma (Pi3K) Bound To The Potent Inhibitor Pikin2
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.51 Å Release Date: 2017-03-15 Classification: TRANSFERASE Ligands: 6K7, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-03-15
Ligands: 6K7, SO4
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Structure Of Phosphoinositide 3-Kinase Gamma (Pi3K) Bound To The Potent Inhibitor Pikin3
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.48 Å Release Date: 2017-03-15 Classification: TRANSFERASE Ligands: 6K5, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-03-15
Ligands: 6K5, SO4
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Tubulin-Bkm120 Complex
Organism: Rattus norvegicus, Gallus gallus, Bos taurus
Method: X-RAY DIFFRACTION Resolution:2.05 Å Release Date: 2017-02-22 Classification: CELL CYCLE Ligands: GTP, MG, CA, GOL, GDP, MES, SD5, ACP |
Organism: Rattus norvegicus, Gallus gallus, Bos taurus
Method: X-RAY DIFFRACTION
Release Date: 2017-02-22
Ligands: GTP, MG, CA, GOL, GDP, MES, SD5, ACP
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Tubulin-Mtd147 Complex
Organism: Rattus norvegicus, Gallus gallus, Bos taurus
Method: X-RAY DIFFRACTION Resolution:2.25 Å Release Date: 2017-02-22 Classification: CELL CYCLE Ligands: GTP, MG, CA, GOL, FB7, GDP, MES, ACP |
Organism: Rattus norvegicus, Gallus gallus, Bos taurus
Method: X-RAY DIFFRACTION
Release Date: 2017-02-22
Ligands: GTP, MG, CA, GOL, FB7, GDP, MES, ACP
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Tubulin-Mtd265 Complex
Organism: Rattus norvegicus, Gallus gallus, Bos taurus
Method: X-RAY DIFFRACTION Resolution:2.15 Å Release Date: 2017-02-22 Classification: CELL CYCLE Ligands: GTP, MG, CA, GOL, 918, GDP, MES, ACP |
Organism: Rattus norvegicus, Gallus gallus, Bos taurus
Method: X-RAY DIFFRACTION
Release Date: 2017-02-22
Ligands: GTP, MG, CA, GOL, 918, GDP, MES, ACP
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Crystal Structure Of Human Pi3Kgamma Complexed With As604850
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.90 Å Release Date: 2005-09-20 Classification: TRANSFERASE Ligands: BYM |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2005-09-20
Ligands: BYM
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Crystal Structure Of Human Pi3Kgamma Complexed With As605240
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.70 Å Release Date: 2005-09-20 Classification: TRANSFERASE Ligands: QYT |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2005-09-20
Ligands: QYT
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Structure Determinants Of Phosphoinositide 3-Kinase Inhibition By Wortmannin, Ly294002, Quercetin, Myricetin And Staurosporine
Organism: Sus scrofa
Method: X-RAY DIFFRACTION Resolution:2.40 Å Release Date: 2000-11-17 Classification: TRANSFERASE Ligands: LY2 |
Organism: Sus scrofa
Method: X-RAY DIFFRACTION
Release Date: 2000-11-17
Ligands: LY2