Search Count: 30
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Complex Between Soybean Trypsin Inhibitor Beta1-Tryptase And A Humanized Fab
Organism: Homo sapiens, Glycine max
Method: X-RAY DIFFRACTION Resolution:2.15 Å Release Date: 2019-10-16 Classification: IMMUNE SYSTEM/HYDROLASE Ligands: EDO |
Organism: Homo sapiens, Glycine max
Method: X-RAY DIFFRACTION
Release Date: 2019-10-16
Ligands: EDO
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Crystal Structure Of Murine Nf-Kappab Inducing Kinase (Nik) In Complex With Compound 1A
Organism: Mus musculus
Method: X-RAY DIFFRACTION Resolution:2.65 Å Release Date: 2018-07-04 Classification: TRANSFERASE Ligands: SO4, ELZ |
Organism: Mus musculus
Method: X-RAY DIFFRACTION
Release Date: 2018-07-04
Ligands: SO4, ELZ
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Crystal Structure Of Murine Nf-Kappab Inducing Kinase (Nik) In Complex With Compound 2F
Organism: Mus musculus
Method: X-RAY DIFFRACTION Resolution:2.84 Å Release Date: 2018-07-04 Classification: TRANSFERASE Ligands: ELW |
Organism: Mus musculus
Method: X-RAY DIFFRACTION
Release Date: 2018-07-04
Ligands: ELW
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Identification Of An Imidazopyridine Scaffold To Generate Potent And Selective Tyk2 Inhibitors That Demonstrate Activity In An In Vivo Psoriasis Model
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.45 Å Release Date: 2017-09-06 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 9ZS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-09-06
Ligands: 9ZS
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Identification Of An Imidazopyridine Scaffold To Generate Potent And Selective Tyk2 Inhibitors That Demonstrate Activity In An In Vivo Psoriasis Model
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.85 Å Release Date: 2017-09-06 Classification: Transferase/Transferase Inhibitor Ligands: 9ZS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-09-06
Ligands: 9ZS
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P110Delta/P85Alpha With Taselisib (Gdc-0032)
Organism: Homo sapiens, Bos taurus
Method: X-RAY DIFFRACTION Resolution:2.91 Å Release Date: 2017-01-11 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 799 |
Organism: Homo sapiens, Bos taurus
Method: X-RAY DIFFRACTION
Release Date: 2017-01-11
Ligands: 799
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Crystal Structure Of Murine Nf-Kappab Inducing Kinase (Nik) Bound To Imidazobenzoxepin Compound 3
Organism: Mus musculus
Method: X-RAY DIFFRACTION Resolution:2.41 Å Release Date: 2017-01-11 Classification: TRANSFERASE Ligands: SO4, 76Z |
Organism: Mus musculus
Method: X-RAY DIFFRACTION
Release Date: 2017-01-11
Ligands: SO4, 76Z
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Crystal Structure Of Murine Nf-Kappab Inducing Kinase (Nik) Bound To Benzoxepin Compound 2
Organism: Mus musculus
Method: X-RAY DIFFRACTION Resolution:2.32 Å Release Date: 2017-01-11 Classification: TRANSFERASE Ligands: 774, SO4 |
Organism: Mus musculus
Method: X-RAY DIFFRACTION
Release Date: 2017-01-11
Ligands: 774, SO4
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Crystal Structure Of Murine Nf-Kappab Inducing Kinase (Nik) Bound To Aryl Pyrrole Fragment 17
Organism: Mus musculus
Method: X-RAY DIFFRACTION Resolution:2.63 Å Release Date: 2017-01-11 Classification: TRANSFERASE Ligands: SO4, 76Y |
Organism: Mus musculus
Method: X-RAY DIFFRACTION
Release Date: 2017-01-11
Ligands: SO4, 76Y
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Itk Kinase Domain With Compound 1 (N-[1-(3-Cyanobenzyl)-1H-Pyrazol-4-Yl]-2H-Indazole-3-Carboxamide)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.58 Å Release Date: 2014-06-04 Classification: transferase/transferase inhibitor Ligands: SO4, 2VT |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-06-04
Ligands: SO4, 2VT
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Itk Kinase Domain With Compound 11 (N-[1-(3-Cyanobenzyl)-1H-Pyrazol-4-Yl]-6-(1H-Pyrazol-4-Yl)-1H-Indazole-3-Carboxamide)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.67 Å Release Date: 2014-06-04 Classification: transferase/transferase inhibitor Ligands: 2VU |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-06-04
Ligands: 2VU
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Itk Kinase Domain With Compound 28 (N-{1-[(1S)-3-(Dimethylamino)-1-Phenylpropyl]-1H-Pyrazol-4-Yl}-6-(1H-Pyrazol-4-Yl)-1H-Indazole-3-Carboxamide)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.82 Å Release Date: 2014-06-04 Classification: transferase/transferase inhibitor Ligands: 2VV |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-06-04
Ligands: 2VV
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Itk Kinase Domain With Compound 27 (N-{1-[(1R)-3-(Dimethylamino)-1-Phenylpropyl]-1H-Pyrazol-4-Yl}-6-(1H-Pyrazol-4-Yl)-1H-Indazole-3-Carboxamide)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.95 Å Release Date: 2014-06-04 Classification: transferase/transferase inhibitor Ligands: 2VW |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-06-04
Ligands: 2VW
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Itk Kinase Domain In Complex With Benzothiazole Inhibitor Compound 12A (1S,2S)-2-{4-[(Dimethylamino)Methyl]Phenyl}-N-[6-(Pyridin-3-Yl)-1,3-Benzothiazol-2-Yl]Cyclopropanecarboxamide (12A)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.67 Å Release Date: 2013-11-13 Classification: transferase/transferase inhibitor Ligands: 29Z |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-11-13
Ligands: 29Z
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Itk Kinase Domain In Complex With Benzothiazole Inhibitor 12B (1S,2S)-2-{4-[(Dimethylamino)Methyl]Phenyl}-N-[6-(1H-Pyrazol-4-Yl)-1,3-Benzothiazol-2-Yl]Cyclopropanecarboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.11 Å Release Date: 2013-11-13 Classification: transferase/transferase inhibitor Ligands: 29Y |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-11-13
Ligands: 29Y
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Tyk2 (Jh1) In Complex With Adenosine Di-Phosphate
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.03 Å Release Date: 2013-08-14 Classification: HYDROLASE Ligands: ADP, MG |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-08-14
Ligands: ADP, MG
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Jak2 Kinase (Jh1 Domain) With 2,6-Dichloro-N-(2-Oxo-2,5-Dihydropyridin-4-Yl)Benzamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.30 Å Release Date: 2013-06-19 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 0X2 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-06-19
Ligands: 0X2
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Tyk2 Kinase (Jh1 Domain) With 2,6-Dichloro-N-(2-Oxo-2,5-Dihydropyridin-4-Yl)Benzamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.30 Å Release Date: 2013-06-19 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: SO4, EDO, GOL, 0X2 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-06-19
Ligands: SO4, EDO, GOL, 0X2
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Tyk2 (Jh1) In Complex With 2,6-Dichloro-N-{2-[(Cyclopropylcarbonyl)Amino]Pyridin-4-Yl}Benzamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.00 Å Release Date: 2013-06-19 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 0X5 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-06-19
Ligands: 0X5
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Jak2 Kinase (Jh1 Domain) In Complex With 2,6-Dichloro-N-{2-[(Cyclopropylcarbonyl)Amino]Pyridin-4-Yl}Benzamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.40 Å Release Date: 2013-06-19 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 0X5 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-06-19
Ligands: 0X5