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Cryo-Em Structure Of The Multi-Component Acyltransferase Complex Mucabc From Streptococcus Macacae At A Stoichiometric Ratio Of 4:2:2
Organism: Streptococcus macacae nctc 11558
Method: ELECTRON MICROSCOPY Release Date: 2026-02-11 Classification: TRANSFERASE Ligands: ZN |
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Cryo-Em Structure Of The Multi-Component Acyltransferase Complex Mucabc From Streptococcus Macacae At A Stoichiometric Ratio Of 4:4:4
Organism: Streptococcus macacae nctc 11558
Method: ELECTRON MICROSCOPY Release Date: 2026-02-11 Classification: TRANSFERASE Ligands: ZN |
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Crystal Structure Of The First Bromodomain Of Human Brd4 In Complex With The Inhibitor Y07004
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.62 Å Release Date: 2023-07-26 Classification: ANTITUMOR PROTEIN Ligands: JCO, GOL, NO3 |
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Organism: Mus musculus
Method: X-RAY DIFFRACTION Resolution:2.30 Å Release Date: 2021-03-03 Classification: EXOCYTOSIS Ligands: IHP |
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Organism: Homo sapiens
Method: SOLUTION NMR Release Date: 2019-05-22 Classification: APOPTOSIS/INHIBITOR Ligands: N8J |
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Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.60 Å Release Date: 2019-05-15 Classification: APOPTOSIS/INHIBITOR Ligands: LOD |
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Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.40 Å Release Date: 2019-05-15 Classification: APOPTOSIS/INHIBITOR Ligands: LOJ |
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Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.60 Å Release Date: 2019-05-15 Classification: APOPTOSIS/INHIBITOR Ligands: N0J |
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Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.48 Å Release Date: 2019-05-15 Classification: APOPTOSIS/INHIBITOR Ligands: N0M |
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Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.70 Å Release Date: 2019-05-15 Classification: APOPTOSIS Ligands: N0P |
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Factor Viia In Complex With The Inhibitor 3-{[(2R)-17-Ethyl-4-Methyl-3,12-Dioxo-7-[(Propan-2-Yl)Sulfonyl]-13-Oxa-4,11-Diazatricyclo[14.2.2.1~6,10~]Henicosa-1(18),6(21),7,9,16,19-Hexaen-2-Yl]Amino}Benzamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.30 Å Release Date: 2017-05-10 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: 82J, CA, SO4, GOL |
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Factor Viia In Complex With The Inhibitor (5R)-5-[(1-Aminoisoquinolin-6-Yl)Amino]-19-(Cyclopropylsulfonyl)-3-Methyl-13-Oxa-3,15-Diazatricyclo[14.3.1.1~6,10~]Henicosa-1(20),6(21),7,9,16,18-Hexaene-4,14-Dione
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.90 Å Release Date: 2017-02-01 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: 7KQ, CA, SO4, GOL |
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Factor Viia In Complex With The Inhibitor (11R)-11-[(1-Aminoisoquinolin-6-Yl)Amino]-16-(Cyclopropylsulfonyl)-13-Methyl-2,13-Diazatricyclo[13.3.1.1~6,10~]Icosa-1(19),6(20),7,9,15,17-Hexaene-3,12-Dione
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.85 Å Release Date: 2017-02-01 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: 7KR, CA, SO4, GOL |
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Factor Viia In Complex With The Inhibitor (5R,11R)-11-[(1-Amino-4-Fluoroisoquinolin-6-Yl)Amino]-16-(Cyclopropylsulfonyl)-7-(2,2-Difluoroethoxy)-5,13-Dimethyl-2,13-Diazatricyclo[13.3.1.1~6,10~]Icosa-1(19),6(20),7,9,15,17-Hexaene-3,12-Dione
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.90 Å Release Date: 2017-02-01 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: 7KS, CA, SO4, GOL |
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Crystal Structure Of The Mbp-Mcl1 Complex With Highly Selective And Potent Inhibitor Of Mcl1
Organism: Escherichia coli o157:h7, Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.20 Å Release Date: 2016-10-26 Classification: APOPTOSIS/INHIBITOR Ligands: 70R |
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Factor Viia In Complex With The Inhibitor 1-[(2R,15R)-2-[(1-Amino-4-Fluoroisoquinolin-6-Yl)Amino]-4,15,20-Trimethyl-3,12-Dioxo-13-Oxa-4,11-Diazatricyclo[14.2.2.1~6,10~]Henicosa-1(18),6,8,10(21),16,19-Hexaen-7-Yl] Cyclobutane-1-Carboxylic Acid
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.82 Å Release Date: 2016-09-28 Classification: Hydrolase/Hydrolase Inhibitor Ligands: 70D, CA, SO4, GOL |
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Factor Viia In Complex With The Inhibitor 1-[(2R,15R)-2-[(1-Amino-4-Fluoroisoquinolin-6-Yl)Amino]-4,15,17-Trimethyl-3,12-Dioxo-13-Oxa-4,11-Diazatricyclo[14.2.2.1~6,10~]Henicosa-1(18),6(21),7,9,16,19-Hexaen-7-Yl]Cyclohexane-1-Carboxylic Acid
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.79 Å Release Date: 2016-09-28 Classification: Hydrolase/Hydrolase inhibitor Ligands: 70C, CA, SO4, GOL |
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Factor Viia In Complex With The Inhibitor (2R,15R)-2-[(1-Aminoisoquinolin-6-Yl)Amino]-4,15,17-Trimethyl-7-[1-(1H-Tetrazol-5-Yl)Cyclopropyl]-13-Oxa-4,11-Diazatricyclo[14.2.2.1~6,10~]Henicosa-1(18),6(21),7,9,16,19-Hexaene-3,12-Dione
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.73 Å Release Date: 2016-09-28 Classification: Hydrolase/Hydrolase Inhibitor Ligands: 70A, CA, SO4, GOL |
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Factor Viia In Complex With The Inhibitor (2R,15R)-2-[(1-Aminoisoquinolin-6-Yl)Amino]-8-Fluoro-7-Hydroxy-4,15,17-Trimethyl-13-Oxa-4,11-Diazatricyclo[14.2.2.1~6,10~]Henicosa-1(18),6(21),7,9,16,19-Hexaene-3,12-Dione
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.06 Å Release Date: 2016-06-22 Classification: Hydrolase/Hydrolase inhibitor Ligands: 67O, CA, SO4, MES |
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Factor Xia In Complex With The Inhibitor 4-(Aminomethyl)-~{N}-[(1~{S})-1-[4-(3-Oxidanyl-1~{H}-Indazol-5-Yl)Pyridin-2-Yl]-2-Phenyl-Ethyl]Cyclohexane-1-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.30 Å Release Date: 2016-04-13 Classification: HYDROLASE/HYDROLASE Inhibitor Ligands: 5SS, SO4, EDO |