Search Count: 24
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Crystal Structure Of Partially Phosphorylated Ret V804M Tyrosine Kinase Domain Complexed With Pdd00018412
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.05 Å Release Date: 2020-03-11 Classification: ONCOPROTEIN Ligands: H6W, EDO, FMT, CL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-03-11
Ligands: H6W, EDO, FMT, CL
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Crystal Structure Of Phosphorylated Ret V804M Tyrosine Kinase Domain Complexed With Pdd00018366
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.88 Å Release Date: 2020-03-11 Classification: ONCOPROTEIN Ligands: H72, FMT |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-03-11
Ligands: H72, FMT
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Polyadpribosyl Glycohydrolase In Complex With Pdd00016690
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.06 Å Release Date: 2018-11-14 Classification: HYDROLASE Ligands: DMS, GOL, SO4, 7JC |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-11-14
Ligands: DMS, GOL, SO4, 7JC
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Polyadpribosyl Glycosidase In Complex With Pdd00017299
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.25 Å Release Date: 2018-11-14 Classification: HYDROLASE Ligands: 73L, DMS, GOL, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-11-14
Ligands: 73L, DMS, GOL, SO4
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Polyadpribosyl Glycohydrolase In Complex With Pdd00013907
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.90 Å Release Date: 2018-11-14 Classification: HYDROLASE Ligands: DMS, GOL, 7JB, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-11-14
Ligands: DMS, GOL, 7JB, SO4
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Polyadpribosyl Glycosidase In Complex With Pdd00014909
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.87 Å Release Date: 2018-11-14 Classification: HYDROLASE Ligands: DMS, GOL, 70J, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-11-14
Ligands: DMS, GOL, 70J, SO4
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Crystal Structure Of Iso-Citrate Dehydrogenase R132H In Complex With A Novel Inhibitor (Compound 13A)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.70 Å Release Date: 2016-12-14 Classification: OXIDOREDUCTASE Ligands: NDP, 6N3 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-12-14
Ligands: NDP, 6N3
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Crystal Structure Of Iso-Citrate Dehydrogenase 1 [Idh1 (R132H)] In Complex With A Novel Inhibitor (Compound 2)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.04 Å Release Date: 2016-12-14 Classification: OXIDOREDUCTASE Ligands: NDP, 6MX |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-12-14
Ligands: NDP, 6MX
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Polyadpribosyl Glycosidase In Complex With Pdd00017262
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.23 Å Release Date: 2016-10-12 Classification: HYDROLASE Ligands: 6WJ, SO4, DMS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-10-12
Ligands: 6WJ, SO4, DMS
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The Discovery Of 2-Substituted Phenol Quinazolines As Potent And Selective Ret Kinase Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.57 Å Release Date: 2016-02-17 Classification: TRANSFERASE Ligands: DTQ, FMT |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-02-17
Ligands: DTQ, FMT
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Crystal Structure Of Rorc In Complex With A Partial Inverse Agonist Compound
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.70 Å Release Date: 2014-11-12 Classification: TRANSCRIPTION Ligands: 3QQ, TLA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-11-12
Ligands: 3QQ, TLA
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The Jak1 Kinase Domain In Complex With Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.10 Å Release Date: 2013-05-22 Classification: TRANSFERASE Ligands: C5I, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-05-22
Ligands: C5I, EDO
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Potent And Selective Inhibitors Of Pi3K-Delta: Obtaining Isoform Selectivity From The Affinity Pocket And Tryptophan Shelf
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.67 Å Release Date: 2013-04-17 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 0SC |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-04-17
Ligands: 0SC
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Potent And Selective Inhibitors Of Pi3K-Delta: Obtaining Isoform Selectivity From The Affinity Pocket And Tryptophan Shelf
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.80 Å Release Date: 2013-04-17 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 0SD |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-04-17
Ligands: 0SD
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Potent And Selective Inhibitors Of Pi3K-Delta: Obtaining Isoform Selectivity From The Affinity Pocket And Tryptophan Shelf
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.94 Å Release Date: 2013-04-17 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 0SE |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-04-17
Ligands: 0SE
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Crystal Structure Of Nik With 11-Bromo-5,6,7,8-Tetrahydropyrimido[4',5':3,4]Cyclohepta[1,2-B]Indol-2-Amine (T28)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.40 Å Release Date: 2013-04-17 Classification: Transferase/Transferase Inhibitor Ligands: T28 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-04-17
Ligands: T28
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Crystal Structure Of Nik With Compound 4-{3-[2-Amino-5-(2-Methoxyethoxy)Pyrimidin-4-Yl]-1H-Indol-5-Yl}-2-Methylbut-3-Yn-2-Ol (13V)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.90 Å Release Date: 2013-04-17 Classification: Transferase/Transferase Inhibitor Ligands: 13V |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-04-17
Ligands: 13V
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Jak1 Kinase (Jh1 Domain) In Complex With Compound 30
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.00 Å Release Date: 2012-05-30 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 0NH |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2012-05-30
Ligands: 0NH
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Jak2 Kinase (Jh1 Domain) In Complex With Compound 30
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.25 Å Release Date: 2012-05-30 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 0NH |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2012-05-30
Ligands: 0NH
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Jak1 Kinase (Jh1 Domain) In Complex With Compound 49
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.90 Å Release Date: 2012-05-30 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 0NL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2012-05-30
Ligands: 0NL