Search Count: 9
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Discovery Of Imidazo[1,2-A]-Pyridine Inhibitors Of Pan-Pi3 Kinases That Are Efficacious In A Mouse Xenograft Model
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.50 Å Release Date: 2016-02-03 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: GOL, 5XV |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-02-03
Ligands: GOL, 5XV
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Serine/Threonine-Protein Kinase Pak1 Complexed With A Dibenzodiazepine: Identification Of An Allosteric Site On Pak1
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.50 Å Release Date: 2015-08-05 Classification: Transferase/transferase inhibitor Ligands: 4PV, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-08-05
Ligands: 4PV, GOL
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Pak1 In Complex With 2-Chloro-5-Ethyl-8-Fluoro-11-(4-Methylpiperazin-1-Yl)-Dibenzodiazepine
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.99 Å Release Date: 2015-06-24 Classification: TRANSFERASE Ligands: 4OQ, MG |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-06-24
Ligands: 4OQ, MG
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Pak1 In Complex With (S)-N-(Tert-Butyl)-3-((2-Chloro-5-Ethyl-8-Fluoro-Dibenzodiazepin-11-Yl)Amino)Pyrrolidine-1-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.20 Å Release Date: 2015-06-24 Classification: TRANSFERASE Ligands: 4OR, MG |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-06-24
Ligands: 4OR, MG
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Structure Of Pi3K Gamma With Imidazopyridine Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.87 Å Release Date: 2013-07-17 Classification: Transferase/Transferase Inhibitor Ligands: 1UJ, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-07-17
Ligands: 1UJ, SO4
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Structure Of Pi3K Gamma With Imidazopyridine Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.25 Å Release Date: 2013-07-17 Classification: Transferase/Transferase Inhibitor Ligands: 1UK, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-07-17
Ligands: 1UK, SO4
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Crystal Structure Of Pi3K Gamma With N6-(3,4-Dimethoxyphenyl)-2-Morpholino-[4,5'-Bipyrimidine]-2',6-Diamine
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.70 Å Release Date: 2012-08-29 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 13K, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2012-08-29
Ligands: 13K, SO4
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Crystal Structure Of Pi3K Gamma With 5-(2,4-Dimorpholinopyrimidin-6-Yl)-4-(Trifluoromethyl)Pyridin-2-Amine
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.20 Å Release Date: 2012-01-04 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: SD5 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2012-01-04
Ligands: SD5
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Crystal Structure Of Pi3K Gamma With 3-(2-Morpholino-6-(Pyridin-3-Ylamino)Pyrimidin-4-Yl)Phenol
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.20 Å Release Date: 2011-08-17 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: P2B |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-08-17
Ligands: P2B