Search Count: 12
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Discovery Of Mk-8189, A Highly Potent And Selective Pde10A Inhibitor For The Treatment Of Schizophrenia
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.02 Å Release Date: 2023-02-08 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: ZN, MG, S9I |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-02-08
Ligands: ZN, MG, S9I
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Pde2 In Complex With Compound 7
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.62 Å Release Date: 2018-09-19 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: ZN, MG, EDO, FKV |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-09-19
Ligands: ZN, MG, EDO, FKV
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Pde2 In Complex With Compound 5
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.54 Å Release Date: 2018-09-19 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: ZN, MG, FKJ, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-09-19
Ligands: ZN, MG, FKJ, EDO
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Pde2 In Complex With Compound 7
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.69 Å Release Date: 2018-09-19 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: ZN, MG, FKG, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-09-19
Ligands: ZN, MG, FKG, EDO
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Identification Of Lxrbeta Selective Agonists For The Treatment Of Alzheimer'S Disease
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.60 Å Release Date: 2016-04-06 Classification: SIGNALING PROTEIN Ligands: 668, PEG |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-04-06
Ligands: 668, PEG
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Identification Of Lxrbeta Selective Agonists For The Treatment Of Alzheimer'S Disease
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.72 Å Release Date: 2016-04-06 Classification: SIGNALING PROTEIN Ligands: 668, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-04-06
Ligands: 668, SO4
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Pde10 Complexed With6-Chloro-N-[(2,4-Dimethylthiazol-5-Yl)Methyl]-5-Methyl-2-[2-(2-Pyridyl)Ethoxy]Pyrimidin-4-Amine
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.10 Å Release Date: 2015-12-02 Classification: hydrolase/hydrolase inhibitor Ligands: ZN, MG, 4PX, 4Y1 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-12-02
Ligands: ZN, MG, 4PX, 4Y1
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Pde10 Complexed With 6-Chloro-N-[(2,4-Dimethylthiazol-5-Yl)Methyl]-5-Methyl-2-[3-(2-Quinolyl)Propoxy]Pyrimidin-4-Amine
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.09 Å Release Date: 2015-10-07 Classification: hydrolase/hydrolase inhibitor Ligands: ZN, MG, 4PX, 4XU |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-10-07
Ligands: ZN, MG, 4PX, 4XU
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Pde10 Complexed With 4,6-Dichloro-2-Cyclopropyl-5-Methyl-Pyrimidine
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.70 Å Release Date: 2015-09-30 Classification: hydrolase/hydrolase inhibitor Ligands: ZN, MG, 4XS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-09-30
Ligands: ZN, MG, 4XS
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Pde10 Complexed With 6-Chloro-2-Cyclopropyl-5-Methyl-Pyrimidin-4-Amine
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.56 Å Release Date: 2015-09-30 Classification: hydrolase/hydrolase inhibitor Ligands: ZN, MG, 4XV |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-09-30
Ligands: ZN, MG, 4XV
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Pde10 Complexed With 6-Chloro-2-Cyclopropyl-5-Methyl-N-Propyl-Pyrimidin-4-Amine
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.05 Å Release Date: 2015-09-30 Classification: hydrolase/hydrolase inhibitor Ligands: ZN, MG, 4XY |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-09-30
Ligands: ZN, MG, 4XY
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Pde10 Complexed With 6-Chloro-2-Cyclopropyl-N-[(2,4-Dimethylthiazol-5-Yl)Methyl]-5-Methyl-Pyrimidin-4-Amine
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.00 Å Release Date: 2015-09-30 Classification: hydrolase/hydrolase inhibitor Ligands: ZN, MG, 4Y2 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-09-30
Ligands: ZN, MG, 4Y2