Search Count: 34
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Crystal Structure Of The Mertk Kinase Domain With Sa4488
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.07 Å Release Date: 2024-10-09 Classification: TRANSFERASE Ligands: A1APF, CL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-10-09
Ligands: A1APF, CL
 |
Mertk In Complex With Small Molecule 6-{1-[([1,1'-Biphenyl]-4-Yl)Carbamoyl]Azetidin-3-Yl}-3-[(1-Methyl-1H-Pyrazol-4-Yl)Amino]Pyrazine-2-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.29 Å Release Date: 2024-10-09 Classification: TRANSFERASE/INHIBITOR Ligands: A1APG, CL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-10-09
Ligands: A1APG, CL
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Mertk In Complex With Small Molecule Inhibitor 6-{1-[6-(3-Hydroxy-3-Methylbutoxy)-1,3-Benzoxazol-2-Yl]Azetidin-3-Yl}-3-[(1-Methyl-1H-Pyrazol-4-Yl)Amino]Pyrazine-2-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.11 Å Release Date: 2024-10-09 Classification: TRANSFERASE/INHIBITOR Ligands: A1APH, CL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-10-09
Ligands: A1APH, CL
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Il17A Homodimer Complexed To Compound 23
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.83 Å Release Date: 2024-04-03 Classification: CYTOKINE Ligands: XCE |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-04-03
Ligands: XCE
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Il17A Complexed To Compound 7
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.47 Å Release Date: 2024-04-03 Classification: CYTOKINE Ligands: XCW, CL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-04-03
Ligands: XCW, CL
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Il17A Homodimer Bound To Compound 10
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.02 Å Release Date: 2022-09-07 Classification: CYTOKINE Ligands: U5I |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-09-07
Ligands: U5I
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Il17A Homodimer Bound To Compound 7
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.49 Å Release Date: 2022-09-07 Classification: CYTOKINE Ligands: U5Q |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-09-07
Ligands: U5Q
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Il17A Homodimer Bound To Compound 6
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.94 Å Release Date: 2022-09-07 Classification: CYTOKINE Ligands: U5X, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-09-07
Ligands: U5X, GOL
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Il17A Homodimer Bound To Compound 5
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.28 Å Release Date: 2022-09-07 Classification: CYTOKINE Ligands: U6C |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-09-07
Ligands: U6C
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Novel Modes Of Inhibition Of Wild-Type Idh1: Direct Covalent Modification Of His315 With Cmpd1
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.65 Å Release Date: 2018-07-25 Classification: OXIDOREDUCTASE/OXIDOREDUCTASE inhibitor Ligands: CA, ICT, DWP |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-07-25
Ligands: CA, ICT, DWP
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Novel Binding Modes Of Inhibition Of Wild-Type Idh1: Allosteric Inhibition With Cmpd2
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.17 Å Release Date: 2018-07-25 Classification: OXIDOREDUCTASE/OXIDOREDUCTASE inhibitor Ligands: LMR, MG, K32 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-07-25
Ligands: LMR, MG, K32
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Novel Modes Of Inhibition Of Wild-Type Idh1: Non-Equivalent Allosteric Inhibition With Cmpd3
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.01 Å Release Date: 2018-07-25 Classification: oxidoreductase/oxidoreductase inhibitor Ligands: NAP, DWM |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-07-25
Ligands: NAP, DWM
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Novel Modes Of Inhibition Of Wild-Type Idh1:Direct Covalent Modification Of His315 With Cmpd11
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.17 Å Release Date: 2018-07-25 Classification: OXIDOREDUCTASE/OXIDOREDUCTASE inhibitor Ligands: MG, ICT, DWJ, NAP |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-07-25
Ligands: MG, ICT, DWJ, NAP
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Novel Modes Of Inhibition Of Wild-Type Idh1: Direct Covalent Modification Of His315 With Cmpd13
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.02 Å Release Date: 2018-07-25 Classification: oxidoreductase/oxidoreductase inhibitor Ligands: ICT, DWG, CA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-07-25
Ligands: ICT, DWG, CA
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Novel Modes Of Inhibition Of Wild-Type Idh1: Direct Covalent Modification Of His315 With Cmpd15
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.92 Å Release Date: 2018-07-25 Classification: oxidoreductase/oxidoreductase inhibitor Ligands: CA, ICT, DWS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-07-25
Ligands: CA, ICT, DWS
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Crystal Structure Of Kdm4A Tandem Tudor Domain In Complex With A Tri-Methyl Lysine Competitive Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.83 Å Release Date: 2018-03-28 Classification: OXIDOREDUCTASE Ligands: 92Y |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-03-28
Ligands: 92Y
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The Novel Suv4-20 Inhibitor A-196 Verifies A Role For Epigenetics In Genomic Integrity
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.22 Å Release Date: 2017-01-25 Classification: TRANSFERASE Ligands: ZN, SAM, 539 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-01-25
Ligands: ZN, SAM, 539
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Crystal Structure Of Hsetd8 In Complex With Histone H4K20 Norleucine Mutant Peptide And S-Adenosylmethionine
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.30 Å Release Date: 2016-12-07 Classification: TRANSFERASE Ligands: SAM |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-12-07
Ligands: SAM
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Crystal Structure Of Zika Virus Ns5 Protein
Organism: Zika virus (strain mr 766)
Method: X-RAY DIFFRACTION Resolution:3.05 Å Release Date: 2016-10-12 Classification: VIRAL PROTEIN Ligands: SAH, ZN |
Organism: Zika virus (strain mr 766)
Method: X-RAY DIFFRACTION
Release Date: 2016-10-12
Ligands: SAH, ZN
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E67-2 Selectively Inhibits Kiaa1718, A Human Histone H3 Lysine 9 Jumonji Demethylase
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.69 Å Release Date: 2012-01-25 Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR Ligands: AKG, NI, CL, SO4, EDO, E67 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2012-01-25
Ligands: AKG, NI, CL, SO4, EDO, E67