Search Count: 29
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Bacterial O-Glcnacase (Oga) With Compound
Organism: Escherichia coli k-12
Method: X-RAY DIFFRACTION Resolution:2.00 Å Release Date: 2021-01-13 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: ACT, VUA, EDO |
Organism: Escherichia coli k-12
Method: X-RAY DIFFRACTION
Release Date: 2021-01-13
Ligands: ACT, VUA, EDO
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Cocomplex Structure Of Deoxyhypusine Synthase With Inhibitor 6-[(1R)-2-Amino-1-Phenylethyl]-3-(Pyridin-3-Yl)-4H,5H,6H,7H-Thieno[2,3-C]Pyridin-7-One
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.23 Å Release Date: 2020-08-19 Classification: TRANSFERASE/INHIBITOR Ligands: 8Y1 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-08-19
Ligands: 8Y1
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Cocomplex Structure Of Deoxyhypusine Synthase With Inhibitor 6-[(2R)-1-Amino-4-Methylpentan-2-Yl]-3-(Pyridin-3-Yl)-4H,5H,6H,7H-Thieno[2,3-C]Pyridin-7-One
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.12 Å Release Date: 2020-08-19 Classification: TRANSFERASE/INHIBITOR Ligands: 91A |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-08-19
Ligands: 91A
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1.65 Angstrom Ternary Complex Of Deoxyhypusine Synthase With Cofactor Nad And Spermidine Mimic Inhibitor Gc7
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.65 Å Release Date: 2020-04-01 Classification: TRANSFERASE/INHIBITOR Ligands: NAD, GC7, MPD |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-04-01
Ligands: NAD, GC7, MPD
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Cocomplex Structure Of Deoxyhypusine Synthase With Inhibitor 6-Bromo-N-(1H-Indol-4-Yl)-1-Benzothiophene-2-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.95 Å Release Date: 2020-04-01 Classification: TRANSFERASE/INHIBITOR Ligands: 8XY |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-04-01
Ligands: 8XY
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Discovery Of A Novel, Highly Potent, And Selective Thieno[3,2-D]Pyrimidinone-Based Cdc7 Inhibitor With A Quinuclidine Moiety (Tak-931) As An Orally Active Investigational Anti-Tumor Agent
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.65 Å Release Date: 2020-01-15 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: O1S |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-01-15
Ligands: O1S
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Discovery Of A Novel, Highly Potent, And Selective Thieno[3,2-D]Pyrimidinone-Based Cdc7 Inhibitor With A Quinuclidine Moiety (Tak-931) As An Orally Active Investigational Anti-Tumor Agent
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.30 Å Release Date: 2020-01-15 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: O1V |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-01-15
Ligands: O1V
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Structure Of Rorgt In Complex With A Novel Inverse Agonist.
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.47 Å Release Date: 2019-07-17 Classification: nuclear protein/agonist Ligands: SO4, MPD, HQ7 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-07-17
Ligands: SO4, MPD, HQ7
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Structure Of Rorgt In Complex With A Novel Agonist.
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.10 Å Release Date: 2019-06-12 Classification: nuclear protein/agonist Ligands: EDO, HOJ |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-06-12
Ligands: EDO, HOJ
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Structure Of Cdk12/Cyck In Complex With A Small Molecule Inhibitor N-(4-(1-Methyl-1H-Pyrazol-4-Yl)Phenyl)-N-((1R,4R)-4-(Quinazolin-2-Ylamino)Cyclohexyl)Acetamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.80 Å Release Date: 2018-08-29 Classification: TRANSFERASE/INHIBITOR Ligands: MG, 8M1 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-08-29
Ligands: MG, 8M1
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Discovery Of Clinical Candidate N-{(1S)-1-[3-Fluoro-4-(Trifluoromethoxy)Phenyl]-2-Methoxyethyl}-7-Methoxy-2-Oxo-2,3-Dihydropyrido[2,3-B]Pyrazine-4(1H)-Carboxamide (Tak-915), A Highly Potent, Selective, And Brain-Penetrating Phosphodiesterase 2A Inhibitor For The Treatment Of Cognitive Disorders
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.86 Å Release Date: 2017-12-27 Classification: Hydrolase/Hydrolase Inhibitor Ligands: ZN, MG, 9GA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-12-27
Ligands: ZN, MG, 9GA
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Discovery Of Clinical Candidate N-{(1S)-1-[3-Fluoro-4-(Trifluoromethoxy)Phenyl]-2-Methoxyethyl}-7-Methoxy-2-Oxo-2,3-Dihydropyrido[2,3-B]Pyrazine-4(1H)-Carboxamide (Tak-915), A Highly Potent, Selective, And Brain-Penetrating Phosphodiesterase 2A Inhibitor For The Treatment Of Cognitive Disorders
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.20 Å Release Date: 2017-08-23 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: ZN, MG, 9GJ |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-08-23
Ligands: ZN, MG, 9GJ
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The Crystal Structure Of Human S-Adenosylhomocysteine Hydrolase (Ahcy) Bound To Oxadiazole Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.40 Å Release Date: 2017-06-28 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: NAD, EDO, 9W1 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-06-28
Ligands: NAD, EDO, 9W1
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The Crystal Structure Of Human S-Adenosylhomocysteine Hydrolase (Ahcy) Bound To Benzothiazole Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.65 Å Release Date: 2017-06-28 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: NAD, 9W4, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-06-28
Ligands: NAD, 9W4, EDO
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Crystal Structure Of Plk1 In Complex With A Novel 5,6-Dihydroimidazolo[1,5-F]Pteridine Inhibitor.
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.50 Å Release Date: 2017-02-22 Classification: Transferase/Transferase Inhibitor Ligands: 79D, ZN |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-02-22
Ligands: 79D, ZN
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Crystal Structure Of Plk1 In Complex With A Novel 5,6-Dihydroimidazolo[1,5-F]Pteridine Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.60 Å Release Date: 2017-02-22 Classification: Transferase/Transferase Inhibitor Ligands: ZN, 79C |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-02-22
Ligands: ZN, 79C
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Crystal Structure Of Human B-Raf Bound To A Dfg-Out Inhibitor Tak-632
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.93 Å Release Date: 2013-07-24 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 1SU |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-07-24
Ligands: 1SU
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Crystal Structure Of Human B-Raf Bound To A Dfg-Out Inhibitor 5B
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.30 Å Release Date: 2013-07-24 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 1SW |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-07-24
Ligands: 1SW
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Crystal Structure Of Plk1 In Complex With A Pyrimidodiazepinone Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.30 Å Release Date: 2013-05-29 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 1J3, ZN, ACT |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-05-29
Ligands: 1J3, ZN, ACT
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Crystal Structure Of Plk1 In Complex With Tak-960
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.50 Å Release Date: 2013-05-29 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: ZN, ACT, 1J4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-05-29
Ligands: ZN, ACT, 1J4