Search Count: 53
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Highly Optimized Cns Penetrant Inhibitors Of Egfr Exon20 Insertion Mutations
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.42 Å Release Date: 2025-02-12 Classification: SIGNALING PROTEIN Ligands: A1IZ7 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-02-12
Ligands: A1IZ7
 |
Highly Optimized Cns Penetrant Inhibitors Of Egfr Exon20 Insertion Mutations
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.91 Å Release Date: 2025-02-12 Classification: SIGNALING PROTEIN Ligands: A1IZ8, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-02-12
Ligands: A1IZ8, SO4
 |
Highly Optimized Cns Penetrant Inhibitors Of Egfr Exon20 Insertion Mutations
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.90 Å Release Date: 2025-02-12 Classification: SIGNALING PROTEIN Ligands: A1IZ9 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-02-12
Ligands: A1IZ9
 |
Highly Optimized Cns Penetrant Inhibitors Of Egfr Exon20 Insertion Mutations
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.22 Å Release Date: 2025-02-12 Classification: SIGNALING PROTEIN Ligands: Q6K, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-02-12
Ligands: Q6K, SO4
 |
Highly Optimized Cns Penetrant Inhibitors Of Egfr Exon20 Insertion Mutations. Compound 51 Bound To Egfrinsnpg [V948R]
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.45 Å Release Date: 2025-02-05 Classification: SIGNALING PROTEIN Ligands: A1IUK |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-02-05
Ligands: A1IUK
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Optimisation Of Potent, Efficacious, Selective And Blood-Brain Barrier Penetrating Inhibitors Targeting Egfr Exon20 Insertion Mutations
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.44 Å Release Date: 2024-11-06 Classification: SIGNALING PROTEIN Ligands: A1H7N, IOD |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-11-06
Ligands: A1H7N, IOD
 |
Optimisation Of Potent, Efficacious, Selective And Blood-Brain Barrier Penetrating Inhibitors Targeting Egfr Exon20 Insertion Mutations
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.02 Å Release Date: 2024-10-16 Classification: SIGNALING PROTEIN Ligands: A1H7O |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-10-16
Ligands: A1H7O
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Cryo-Em Structure Of P97:Ubxd1 Closed State
Organism: Homo sapiens
Method: ELECTRON MICROSCOPY Release Date: 2023-06-21 Classification: CHAPERONE, HYDROLASE Ligands: ADP |
Organism: Homo sapiens
Method: ELECTRON MICROSCOPY
Release Date: 2023-06-21
Ligands: ADP
 |
Cryo-Em Structure Of P97:Ubxd1 Open State
Organism: Homo sapiens
Method: ELECTRON MICROSCOPY Release Date: 2023-06-21 Classification: CHAPERONE, HYDROLASE Ligands: ADP |
Organism: Homo sapiens
Method: ELECTRON MICROSCOPY
Release Date: 2023-06-21
Ligands: ADP
 |
Cryo-Em Structure Of P97:Ubxd1 Vim-Only State
Organism: Homo sapiens
Method: ELECTRON MICROSCOPY Release Date: 2023-06-21 Classification: CHAPERONE, HYDROLASE Ligands: ADP |
Organism: Homo sapiens
Method: ELECTRON MICROSCOPY
Release Date: 2023-06-21
Ligands: ADP
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Cryo-Em Structure Of P97:Ubxd1 Meta State
Organism: Homo sapiens
Method: ELECTRON MICROSCOPY Release Date: 2023-06-21 Classification: CHAPERONE, HYDROLASE Ligands: ADP |
Organism: Homo sapiens
Method: ELECTRON MICROSCOPY
Release Date: 2023-06-21
Ligands: ADP
 |
Cryo-Em Structure Of P97:Ubxd1 Para State
Organism: Homo sapiens
Method: ELECTRON MICROSCOPY Release Date: 2023-06-21 Classification: CHAPERONE, HYDROLASE Ligands: ADP |
Organism: Homo sapiens
Method: ELECTRON MICROSCOPY
Release Date: 2023-06-21
Ligands: ADP
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Cryo-Em Structure Of P97:Ubxd1 Pub-In State
Organism: Homo sapiens
Method: ELECTRON MICROSCOPY Release Date: 2023-06-21 Classification: CHAPERONE, HYDROLASE Ligands: ADP |
Organism: Homo sapiens
Method: ELECTRON MICROSCOPY
Release Date: 2023-06-21
Ligands: ADP
 |
Cryo-Em Structure Of P97:Ubxd1 H4-Bound State
Organism: Homo sapiens
Method: ELECTRON MICROSCOPY Resolution:4.12 Å Release Date: 2023-06-21 Classification: CHAPERONE, HYDROLASE Ligands: ADP |
Organism: Homo sapiens
Method: ELECTRON MICROSCOPY
Release Date: 2023-06-21
Ligands: ADP
 |
Cryo-Em Structure Of P97:Ubxd1 Lariat Mutant
Organism: Homo sapiens
Method: ELECTRON MICROSCOPY Release Date: 2023-06-21 Classification: CHAPERONE, HYDROLASE Ligands: ADP |
Organism: Homo sapiens
Method: ELECTRON MICROSCOPY
Release Date: 2023-06-21
Ligands: ADP
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Estrogen Receptor Alpha In Complex With Compound 29
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.68 Å Release Date: 2023-02-01 Classification: TRANSCRIPTION Ligands: H09 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-02-01
Ligands: H09
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Oestrogen Receptor Ligand Binding Domain In Complex With Compound 38
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.90 Å Release Date: 2023-02-01 Classification: GENE REGULATION Ligands: GZI |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-02-01
Ligands: GZI
 |
Oestrogen Receptor Ligand Binding Domain In Complex With Compound 16
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.80 Å Release Date: 2021-01-20 Classification: GENE REGULATION Ligands: QNE |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-01-20
Ligands: QNE
 |
Oestrogen Receptor Ligand Binding Domain In Complex With Compound 28
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.97 Å Release Date: 2021-01-20 Classification: GENE REGULATION Ligands: QNH |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-01-20
Ligands: QNH
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Oestrogen Receptor Ligand Binding Domain In Complex With Compound 18
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.00 Å Release Date: 2021-01-20 Classification: GENE REGULATION Ligands: QNK |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-01-20
Ligands: QNK