Search Count: 55
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Discovery Of A Small Molecule Itk And Pan-Trk Kinase Inhibitor (Pf-07245303) For The Potential Topical Treatment Of Atopic Dermatitis
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.35 Å Release Date: 2025-11-19 Classification: SIGNALING PROTEIN Ligands: A1B66 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-11-19
Ligands: A1B66
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Cryo-Em Structure Of Ccr6 Bound By Pf-07054894 And Oxm2
Organism: Homo sapiens, Synthetic construct
Method: ELECTRON MICROSCOPY Resolution:3.35 Å Release Date: 2025-10-01 Classification: MEMBRANE PROTEIN Ligands: A1A1W, A1CH1 |
Organism: Homo sapiens, Synthetic construct
Method: ELECTRON MICROSCOPY
Release Date: 2025-10-01
Ligands: A1A1W, A1CH1
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Pad2 With An Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.18 Å Release Date: 2025-07-30 Classification: HYDROLASE Ligands: A1CE0, CA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-07-30
Ligands: A1CE0, CA
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Potent Inhibition Of The Protein Arginine Deiminases (Pad1-4) By Targeting A Ca2+ Dependent Allosteric Binding Site
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.77 Å Release Date: 2025-05-28 Classification: HYDROLASE Ligands: CA, A1A8O |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-05-28
Ligands: CA, A1A8O
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Inhibiting Peptidylarginine Deiminases (Pad1-4) By Targeting A Ca2+ Dependent Allosteric Binding Site
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.44 Å Release Date: 2025-05-28 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: CA, A1BZK |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-05-28
Ligands: CA, A1BZK
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Potent Inhibition Of The Protein Arginine Deiminases (Pad1-4) By Targeting A Ca2+ Dependent Allosteric Binding Site
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.41 Å Release Date: 2025-05-28 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: A1A9P, 3YZ |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-05-28
Ligands: A1A9P, 3YZ
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Crystal Structure Of The Human Pad2 Protein Bound To Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.64 Å Release Date: 2024-10-09 Classification: HYDROLASE Ligands: A1AJA, ACT, CA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-10-09
Ligands: A1AJA, ACT, CA
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Crystal Structure Of The Human Pad2 Protein Bound To Small Molecule
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.95 Å Release Date: 2024-10-09 Classification: HYDROLASE Ligands: MPD, A1AJB, ACT, CA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-10-09
Ligands: MPD, A1AJB, ACT, CA
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Crystal Structure Of The Human Pad2 Protein Bound To Small Molecule
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.00 Å Release Date: 2024-10-09 Classification: HYDROLASE Ligands: ACT, CA, A1AJC |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-10-09
Ligands: ACT, CA, A1AJC
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Cryo-Em Structure Of Ccr6 Bound By Sqa1 And Oxm2
Organism: Homo sapiens, Synthetic construct
Method: ELECTRON MICROSCOPY Release Date: 2024-09-11 Classification: MEMBRANE PROTEIN Ligands: CLR, EBX, A1A1W |
Organism: Homo sapiens, Synthetic construct
Method: ELECTRON MICROSCOPY
Release Date: 2024-09-11
Ligands: CLR, EBX, A1A1W
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Cryo-Em Structure Of Ccr6 Bound By Sqa1 And Oxm1
Organism: Homo sapiens, Synthetic construct
Method: ELECTRON MICROSCOPY Release Date: 2024-09-11 Classification: MEMBRANE PROTEIN Ligands: CLR, EBX, A1A2A |
Organism: Homo sapiens, Synthetic construct
Method: ELECTRON MICROSCOPY
Release Date: 2024-09-11
Ligands: CLR, EBX, A1A2A
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Human Retenoid-Related Orphan Receptor-Gamma (Rorc2) Ligand-Binding Domain In Complex With Compound 5 Andindazole Acid Bound In H12-Pocket
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.85 Å Release Date: 2023-03-01 Classification: DNA BINDING PROTEIN Ligands: LKY, 4Y5, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-03-01
Ligands: LKY, 4Y5, SO4
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Human Retenoid-Related Orphan Receptor-Gamma (Rorc2) Ligand-Binding Domain In Complex With Compound 6A Andindazole Acid Bound In H12-Pocket
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.18 Å Release Date: 2023-03-01 Classification: DNA BINDING PROTEIN Ligands: XNR, 4Y5 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-03-01
Ligands: XNR, 4Y5
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Human Retenoid-Related Orphan Receptor-Gamma (Rorc2) Ligand-Binding Domain In Complex With Compound 8 Andindazole Acid Bound In H12-Pocket
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.30 Å Release Date: 2023-03-01 Classification: DNA BINDING PROTEIN Ligands: XO5, XNX |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-03-01
Ligands: XO5, XNX
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Crystal Structure Of Tyk2 Kinase With Compound 13
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.09 Å Release Date: 2020-04-08 Classification: TRANSFERASE/INHIBITOR Ligands: R5D |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-04-08
Ligands: R5D
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Crystal Structure Of Tyk2 Kinase With Compound 14
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.15 Å Release Date: 2020-04-08 Classification: TRANSFERASE/INHIBITOR Ligands: R4Y |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-04-08
Ligands: R4Y
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Crystal Structure Of Tyk2 Kinase With Compound 19
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.18 Å Release Date: 2020-04-08 Classification: TRANSFERASE/INHIBITOR Ligands: R4V |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-04-08
Ligands: R4V
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Crystal Structure Of Tyk2 Kinase With Compound 10
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.30 Å Release Date: 2020-04-08 Classification: TRANSFERASE/INHIBITOR Ligands: R4S |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-04-08
Ligands: R4S
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Crystal Structure Of Jak1 Kinase With Compound 10
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.11 Å Release Date: 2020-04-08 Classification: TRANSFERASE/INHIBITOR Ligands: R4S |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-04-08
Ligands: R4S
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Crystal Structure Of Mouse Btk Kinase Domain In Complex With Compound 9A
Organism: Mus musculus
Method: X-RAY DIFFRACTION Resolution:2.80 Å Release Date: 2019-01-30 Classification: TRANSFERASE Ligands: JVP |
Organism: Mus musculus
Method: X-RAY DIFFRACTION
Release Date: 2019-01-30
Ligands: JVP