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6H3Q image
Crystal Structure Of Human Carbonic Anhydrase Ii In Complex With The 4-(5-(Chloromethyl)-1,3-Selenazol-2-Yl)Benzenesulfonamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:1.31 Å Release Date: 2019-07-17
Classification: LYASE
Ligands: ZN, FMH

6EBE image
Bioreductive 4-Hydroxy-3-Nitro-5-Ureido-Benzenesulfonamides Selectively Target The Tumor-Associated Carbonic Anhydrase Isoforms Ix And Xii And Show Hypoxia-Enhanced Cytotoxicity Against Human Cancer Cell Lines.

6ECZ image
Bioreductive 4-Hydroxy-3-Nitro-5-Ureido-Benzenesulfonamides Selectively Target The Tumor-Associated Carbonic Anhydrase Isoforms Ix And Xii And Show Hypoxia-Enhanced Cytotoxicity Against Human Cancer Cell Lines.

6EDA image
Bioreductive 4-Hydroxy-3-Nitro-5-Ureido-Benzenesulfonamides Selectively Target The Tumor-Associated Carbonic Anhydrase Isoforms Ix And Xii And Show Hypoxia-Enhanced Cytotoxicity Against Human Cancer Cell Lines.

6EEA image
Bioreductive 4-Hydroxy-3-Nitro-5-Ureido-Benzenesulfonamides Selectively Target The Tumor-Associated Carbonic Anhydrase Isoforms Ix And Xii And Show Hypoxia-Enhanced Cytotoxicity Against Human Cancer Cell Lines.

6EEH image
Bioreductive 4-Hydroxy-3-Nitro-5-Ureido-Benzenesulfonamides Selectively Target The Tumor-Associated Carbonic Anhydrase Isoforms Ix And Xii And Show Hypoxia-Enhanced Cytotoxicity Against Human Cancer Cell Lines.

6EEO image
Bioreductive 4-Hydroxy-3-Nitro-5-Ureido-Benzenesulfonamides Selectively Target The Tumor-Associated Carbonic Anhydrase Isoforms Ix And Xii And Show Hypoxia-Enhanced Cytotoxicity Against Human Cancer Cell Lines.

6CEH image
Design, Synthesis, X-Ray And Biological Activities Of Selenides Bearing The Benzenesulfonamide Moiety As New Class Of Agents For Prevention Of Diabetic Cerebrovascular Pathology
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