Search Count: 19
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Fgfr2 Kinase Domain Bound To Reversible Inhibitor Cmpd 3
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.24 Å Release Date: 2024-02-14 Classification: ONCOPROTEIN Ligands: GOL, GSH, WXQ |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-02-14
Ligands: GOL, GSH, WXQ
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Fgfr2 Kinase Domain Bound To Irreversible Inhibitor Cmpd 10
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.33 Å Release Date: 2024-02-14 Classification: Transferase/Inhibitor Ligands: GOL, UIM, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-02-14
Ligands: GOL, UIM, SO4
 |
Discovery And Clinical Validation Of Rly-4008, The First Highly Selective Fgfr2 Inhibitor With Activity Across Fgfr2 Alterations And Resistance Mutations
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.79 Å Release Date: 2023-06-07 Classification: TRANSFERASE/INHIBITOR Ligands: WCJ |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-06-07
Ligands: WCJ
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Non-Receptor Protein Tyrosine Phosphatase Shp2 In Complex With Allosteric Inhibitor Tno155
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.17 Å Release Date: 2020-09-23 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: VKS, PO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-09-23
Ligands: VKS, PO4
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Non-Receptor Protein Tyrosine Phosphatase Shp2 In Complex With Allosteric Inhibitor Compound 24
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.92 Å Release Date: 2020-09-23 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: VKP, PO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-09-23
Ligands: VKP, PO4
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Melk In Complex With Nvs-Melk5
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.77 Å Release Date: 2017-03-01 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 6PV |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-03-01
Ligands: 6PV
 |
Idh1 R132H In Complex With Idh146
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.48 Å Release Date: 2017-02-08 Classification: OXIDOREDUCTASE Ligands: NDP, 70Q, SO4, EDO, DMS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-02-08
Ligands: NDP, 70Q, SO4, EDO, DMS
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Idh1 R132H In Complex With Idh125
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.34 Å Release Date: 2017-02-08 Classification: OXIDOREDUCTASE Ligands: NDP, 70P, FLC |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-02-08
Ligands: NDP, 70P, FLC
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Structure Of Idh2 Mutant R172K
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.10 Å Release Date: 2017-02-08 Classification: OXIDOREDUCTASE Ligands: NDP, PEG |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-02-08
Ligands: NDP, PEG
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Structure Of Idh2 Mutant R140Q
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.87 Å Release Date: 2017-02-08 Classification: OXIDOREDUCTASE Ligands: NAP, EPE |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-02-08
Ligands: NAP, EPE
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Idh1 R132H Mutant In Complex With Idh889
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.20 Å Release Date: 2017-01-25 Classification: OXIDOREDUCTASE Ligands: FLC, 7J2, NDP |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-01-25
Ligands: FLC, 7J2, NDP
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Melk In Complex With Nvs-Melk1
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.85 Å Release Date: 2016-06-01 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 6BJ |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-06-01
Ligands: 6BJ
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Melk In Complex With Nvs-Melk8A
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.79 Å Release Date: 2016-06-01 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 6BF |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-06-01
Ligands: 6BF
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Melk In Complex With Nvs-Melk8F
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.96 Å Release Date: 2016-06-01 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 6BE |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-06-01
Ligands: 6BE
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Melk In Complex With Nvs-Melk12B
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.14 Å Release Date: 2016-06-01 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 6BB |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-06-01
Ligands: 6BB
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Tankyrase-1 Complexed With Small Molecule Inhibitor N-[(4-Oxo-3,4-Dihydroquinazolin-2-Yl)Methyl]-3-Phenyl-N-(Thiophen-2-Ylmethyl)Propanamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.05 Å Release Date: 2013-08-14 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: ZN, SO4, 1XO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-08-14
Ligands: ZN, SO4, 1XO
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Tankyrase-1 Complexed With Small Molecule Inhibitor 4-Chloro-5-Cyano-N-{2-[4-(4-Fluorobenzoyl)Piperidin-1-Yl]Ethyl}-2-Methoxybenzamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.20 Å Release Date: 2013-08-14 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: SO4, NA, 1XP |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-08-14
Ligands: SO4, NA, 1XP
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Tankyrase-1 Complexed With Small Molecule Inhibitor 2-[4-(4-Fluorobenzoyl)Piperidin-1-Yl]-N-[(4-Oxo-3,5,7,8-Tetrahydro-4H-Pyrano[4,3-D]Pyrimidin-2-Yl)Methyl]-N-(Thiophen-2-Ylmethyl)Acetamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.52 Å Release Date: 2013-08-14 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: ZN, 1XQ, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-08-14
Ligands: ZN, 1XQ, SO4
 |
Crystal Structure Of Human Bcl-2 In Complex With A Small Molecule Inhibitor Targeting Bcl-2 Bh3 Domain Interactions
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.10 Å Release Date: 2013-07-10 Classification: APOPTOSIS/INHIBITOR Ligands: 1E9 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-07-10
Ligands: 1E9