Search Count: 15
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Crystal Structure Analysis Of Cruzain With Three Fragments: 1 (N-(1H-Benzimidazol-2-Yl)-1,3-Dimethyl-Pyrazole-4-Carboxamide), 6 (2-Amino-4,6-Difluorobenzothiazole) And 9 (N-(1H-Benzimidazol-2-Yl)-3-(4-Fluorophenyl)-1H-Pyrazole-4-Carboxamide).
Organism: Trypanosoma cruzi
Method: X-RAY DIFFRACTION Resolution:3.27 Å Release Date: 2015-04-08 Classification: HYDROLASE/HYDROLASE Inhibitor Ligands: 3H5, 3H6, 3H7 |
Organism: Trypanosoma cruzi
Method: X-RAY DIFFRACTION
Release Date: 2015-04-08
Ligands: 3H5, 3H6, 3H7
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Crystal Structure Analysis Of Cruzain Bound To The No-Covalent Analog Of Wrr-483 (Wrr-669)
Organism: Trypanosoma cruzi
Method: X-RAY DIFFRACTION Resolution:2.51 Å Release Date: 2015-03-11 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: 2VC, EDO |
Organism: Trypanosoma cruzi
Method: X-RAY DIFFRACTION
Release Date: 2015-03-11
Ligands: 2VC, EDO
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Crystal Structure Analysis Of Cruzain With Fragment 1 (N-(1H-Benzimidazol-2-Yl)-1,3-Dimethyl-Pyrazole-4-Carboxamide)
Organism: Trypanosoma cruzi
Method: X-RAY DIFFRACTION Resolution:2.70 Å Release Date: 2015-03-04 Classification: HYDROLASE/HYDROLASE Inhibitor Ligands: 3H5 |
Organism: Trypanosoma cruzi
Method: X-RAY DIFFRACTION
Release Date: 2015-03-04
Ligands: 3H5
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Crystal Structure Analysis Of Cruzain Bound To Vinyl Sulfone Analog Of Wrr-483 (Wrr-666)
Organism: Trypanosoma cruzi
Method: X-RAY DIFFRACTION Resolution:1.27 Å Release Date: 2014-11-12 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: 2V5 |
Organism: Trypanosoma cruzi
Method: X-RAY DIFFRACTION
Release Date: 2014-11-12
Ligands: 2V5
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Crystal Structure Of Human Thymidylate Synthase Y202A In Inactive Conformation.
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.31 Å Release Date: 2014-08-20 Classification: TRANSFERASE Ligands: SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-08-20
Ligands: SO4
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Crystal Structure Of His-Tagged Human Thymidylate Synthase R175A Mutant
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.03 Å Release Date: 2014-05-14 Classification: TRANSFERASE Ligands: SO4, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-05-14
Ligands: SO4, EDO
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Crystal Structure Of E.Coli Thymidylate Synthase With Dump And The Bgc 945 Inhibitor
Organism: Escherichia coli
Method: X-RAY DIFFRACTION Resolution:1.75 Å Release Date: 2013-12-25 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: UMP, MG, 1JY, UMC |
Organism: Escherichia coli
Method: X-RAY DIFFRACTION
Release Date: 2013-12-25
Ligands: UMP, MG, 1JY, UMC
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Allosteric Peptidic Inhibitor Of Human Thymidylate Synthase That Stabilizes Inactive Conformation Of The Enzyme.
Organism: Homo sapiens, Synthetic
Method: X-RAY DIFFRACTION Resolution:2.00 Å Release Date: 2013-03-06 Classification: transferase/transferase inhibitor Ligands: SO4 |
Organism: Homo sapiens, Synthetic
Method: X-RAY DIFFRACTION
Release Date: 2013-03-06
Ligands: SO4
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Structure Of Human Thymidylate Synthase In Inactive Conformation With A Novel Non-Peptidic Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.30 Å Release Date: 2012-11-14 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: SO4, 0MZ, 9MZ |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2012-11-14
Ligands: SO4, 0MZ, 9MZ
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Hemopexin-Like Domain Of Matrix Metalloproteinase 14
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.70 Å Release Date: 2009-02-10 Classification: HYDROLASE |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2009-02-10
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Mmp-9 Active Site Mutant With Barbiturate Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.00 Å Release Date: 2007-06-19 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: ZN, CA, CL, 4MR |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2007-06-19
Ligands: ZN, CA, CL, 4MR
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Mmp-9 Active Site Mutant With Phosphinate Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.00 Å Release Date: 2007-06-19 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: ZN, CA, CL, 5MR |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2007-06-19
Ligands: ZN, CA, CL, 5MR
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Mmp-9 Active Site Mutant With Iodine-Labeled Carboxylate Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.00 Å Release Date: 2007-06-19 Classification: HYDROLASE Ligands: ZN, CA, CL, 6MR |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2007-06-19
Ligands: ZN, CA, CL, 6MR
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Mmp-9 Active Site Mutant With Trifluoromethyl Hydroxamate Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.20 Å Release Date: 2007-06-19 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: ZN, CA, CL, 7MR |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2007-06-19
Ligands: ZN, CA, CL, 7MR
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Mmp-9 Active Site Mutant With Difluoro Butanoic Acid Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.90 Å Release Date: 2007-06-19 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: ZN, CA, CL, 8MR |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2007-06-19
Ligands: ZN, CA, CL, 8MR