Search Count: 34
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Crystal Structure Of Human Wd Repeat-Containing Protein 5 In Complex With 4-(3,5-Dimethoxybenzyl)-9-(4-Fluoro-2-Methylphenyl)-7-((2-Imino-3-Methyl-2,3-Dihydro-1H-Imidazol-1-Yl)Methyl)-3,4-Dihydrobenzo[F][1,4]Oxazepin-5(2H)-One (Compound 8)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.01 Å Release Date: 2023-12-20 Classification: TRANSCRIPTION Ligands: VV3 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-12-20
Ligands: VV3
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Wd Repeat-Containing Protein 5 Complexed With 4-(7-((1H-Imidazol-1-Yl)Methyl)-5-(1-Methyl-3-(Trifluoromethyl)-1H-Pyrazol-4-Yl)-1-Oxo-3,4-Dihydroisoquinolin-2(1H)-Yl)-6-Ethyl-N-Methylquinoline-8-Carboxamide (Compound 10)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.55 Å Release Date: 2023-01-11 Classification: TRANSCRIPTION Ligands: BEN, UY9 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-01-11
Ligands: BEN, UY9
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Discovery Of Potent Orally Bioavailable Wd Repeat Domain 5 (Wdr5) Inhibitors Using A Pharmacophore-Based Optimization
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.81 Å Release Date: 2022-05-04 Classification: Transcription/Transcription Inhibitor Ligands: MBU |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-05-04
Ligands: MBU
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Wdr5 Bound To 2-(3,5-Dimethoxybenzyl)-7-((2-Methyl-1H-Imidazol-1-Yl)Methyl)-5-(1-Methyl-3-(Trifluoromethyl)-1H-Pyrazol-4-Yl)-3,4-Dihydroisoquinolin-1(2H)-One
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.90 Å Release Date: 2022-04-27 Classification: Transcription/Transcription Inhibitor Ligands: BEN, M4U |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-04-27
Ligands: BEN, M4U
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Wdr5 In Complex With Myc Site Fragment Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.26 Å Release Date: 2020-04-15 Classification: TRANSCRIPTION Ligands: Q8G |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-04-15
Ligands: Q8G
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Wdr5 In Complex With Myc Site Fragment Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.26 Å Release Date: 2020-04-15 Classification: TRANSCRIPTION Ligands: Q8D |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-04-15
Ligands: Q8D
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Discovery Of Fragment-Inspired Heterocyclic Benzenesulfonmides As Inhibitors Of The Wdr5-Myc Interaction
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.60 Å Release Date: 2020-04-15 Classification: TRANSCRIPTION Ligands: Q8P |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-04-15
Ligands: Q8P
 |
Discovery Of Fragment-Inspired Heterocyclic Benzenesulfonmides As Inhibitors Of The Wdr5-Myc Interaction
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.60 Å Release Date: 2020-04-15 Classification: TRANSCRIPTION Ligands: Q8M |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-04-15
Ligands: Q8M
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Discovery Of Fragment-Inspired Heterocyclic Benzenesulfonmides As Inhibitors Of The Wdr5-Myc Interaction
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.53 Å Release Date: 2020-04-15 Classification: TRANSCRIPTION Ligands: Q8S |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-04-15
Ligands: Q8S
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Discovery Of Fragment-Inspired Heterocyclic Benzenesulfonamides As Inhibitors Of The Wdr5-Myc Interaction
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.49 Å Release Date: 2020-04-15 Classification: TRANSCRIPTION Ligands: QBS, SO4, DMS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-04-15
Ligands: QBS, SO4, DMS
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Discovery Of Fragment-Inspired Heterocyclic Benzenesulfonamides As Inhibitors Of The Wdr5-Myc Interaction
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.73 Å Release Date: 2020-04-15 Classification: TRANSCRIPTION Ligands: QBP |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-04-15
Ligands: QBP
 |
Discovery Of Fragment-Inspired Heterocyclic Benzenesulfonamides As Inhibitors Of The Wdr5-Myc Interaction
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.60 Å Release Date: 2020-04-15 Classification: TRANSCRIPTION Ligands: QBM |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-04-15
Ligands: QBM
 |
Discovery Of Fragment-Inspired Heterocyclic Benzenesulfonmides As Inhibitors Of The Wdr5-Myc Interaction
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.53 Å Release Date: 2020-04-15 Classification: TRANSCRIPTION Ligands: QF1 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-04-15
Ligands: QF1
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Discovery And Structure-Based Optimization Of Potent And Selective Wdr5 Inhibitors Containing A Dihydroisoquinolinone Bicyclic Core
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.85 Å Release Date: 2020-01-01 Classification: TRANSCRIPTION Ligands: Q41 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-01-01
Ligands: Q41
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Wd Repeat-Containing Protein 5 Complexed With N-[(3,5-Dimethoxyphenyl)Methyl]-4'-Fluoro-5-{[(2E)-2-Imino-3-Methyl-2,3-Dihydro-1H-Imidazol-1-Yl]Methyl}-2'-Methyl[1,1'-Biphenyl]-3-Carboxamide (Compound 13)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.02 Å Release Date: 2020-01-01 Classification: GENE REGULATION/INHIBITOR Ligands: Q6S |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-01-01
Ligands: Q6S
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Discovery And Optimization Of Salicyclic Acid-Derived Sulfonamide Inhibitors Of The Wdr5:Myc Protein-Protein Interaction
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.80 Å Release Date: 2019-12-04 Classification: TRANSCRIPTION Ligands: Q0S |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-12-04
Ligands: Q0S
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Discovery And Optimization Of Salicyclic Acid-Derived Sulfonamide Inhibitors Of The Wdr5:Myc Protein-Protein Interaction
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.53 Å Release Date: 2019-12-04 Classification: TRANSCRIPTION Ligands: Q0M |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-12-04
Ligands: Q0M
 |
Discovery And Optimization Of Salicyclic Acid-Derived Sulfonamide Inhibitors Of The Wdr5:Myc Protein-Protein Interaction
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.20 Å Release Date: 2019-12-04 Classification: TRANSCRIPTION/INHIBITOR Ligands: Q0Y |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-12-04
Ligands: Q0Y
 |
Discovery And Optimization Of Salicyclic Acid-Derived Sulfonamide Inhibitors Of The Wdr5:Myc Protein-Protein Interaction
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.55 Å Release Date: 2019-12-04 Classification: TRANSCRIPTION Ligands: Q1J |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-12-04
Ligands: Q1J
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Discovery And Optimization Of Salicyclic Acid-Derived Sulfonamide Inhibitors Of The Wdr5:Myc Protein-Protein Interaction
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.26 Å Release Date: 2019-12-04 Classification: TRANSCRIPTION Ligands: Q1M |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-12-04
Ligands: Q1M