Search Count: 19
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Crystal Structure Of Dlk In Complex With Inhibitor Dn0011197
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.79 Å Release Date: 2022-12-14 Classification: SIGNALING PROTEIN,TRANSFERASE/INHIBITOR Ligands: SIQ |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-12-14
Ligands: SIQ
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Brain Delivery Of Therapeutic Proteins Using An Fc Fragment Blood-Brain Barrier Transport Vehicle In Mice And Monkeys
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.38 Å Release Date: 2020-06-10 Classification: PROTEIN TRANSPORT |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-06-10
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Chain A. Udp-3-O-[3-Hydroxymyristoyl] N-Acetylglucosamine Deacetylase Pa-Lpxc Complexed With (R)-3-((S)-3-(4-(Cyclopropylethynyl)Phenyl)-2-Oxooxazolidin-5-Yl)-N-Hydroxy-2-Methyl-2-(Methylsulfonyl)Propenamide
Organism: Pseudomonas aeruginosa (strain atcc 15692 / dsm 22644 / cip 104116 / jcm 14847 / lmg 12228 / 1c / prs 101 / pao1)
Method: X-RAY DIFFRACTION Resolution:1.80 Å Release Date: 2019-01-23 Classification: HYDROLASE Ligands: JBA, ZN |
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Crystal Structure Of Btk Kinase Domain Complexed With 6-(Dimethylamino)-2-[2-(Hydroxymethyl)-3-[1-Methyl-5-[[5-(Morpholine-4-Carbonyl)-2-Pyridyl]Amino]-6-Oxo-3-Pyridyl]Phenyl]-3,4-Dihydroisoquinolin-1-One
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.70 Å Release Date: 2014-12-24 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 3OU, DMS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-12-24
Ligands: 3OU, DMS
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Crystal Structure Of Btk Kinase Domain Complexed With 6-(Dimethylamino)-8-Fluoro-2-[2-(Hydroxymethyl)-3-[1-Methyl-5-[[5-(Morpholine-4-Carbonyl)-2-Pyridyl]Amino]-6-Oxo-3-Pyridyl]Phenyl]Isoquinolin-1-One
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.17 Å Release Date: 2014-12-24 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 3OV, DMS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-12-24
Ligands: 3OV, DMS
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Crystal Structure Of Btk Kinase Domain Complexed With 2-[8-Fluoro-2-[2-(Hydroxymethyl)-3-[1-Methyl-5-[[5-(4-Methylpiperazin-1-Yl)-2-Pyridyl]Amino]-6-Oxo-3-Pyridyl]Phenyl]-1-Oxo-3,4-Dihydroisoquinolin-6-Yl]-2-Methyl-Propanenitrile
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.50 Å Release Date: 2014-12-24 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 3P0 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-12-24
Ligands: 3P0
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Crystal Structure Of Rat Cyclophilin D In Complex With A Potent Nonimmunosuppressive Inhibitor
Organism: Rattus norvegicus, Synthetic construct
Method: X-RAY DIFFRACTION Resolution:2.39 Å Release Date: 2014-11-12 Classification: ISOMERASE/ISOMERASE Inhibitor Ligands: P6G, SO4 |
Organism: Rattus norvegicus, Synthetic construct
Method: X-RAY DIFFRACTION
Release Date: 2014-11-12
Ligands: P6G, SO4
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Crystal Structure Of Btk Kinase Domain Complexed With 4-Tert-Butyl-N-(3-{8-[4-(4-Methyl-Piperazine-1-Carbonyl)-Phenylamino]-Imidazo[1,2-A]Pyrazin-6-Yl}-Phenyl)-Benzamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.55 Å Release Date: 2014-05-14 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 481, DMS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-05-14
Ligands: 481, DMS
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Crystal Structure Of Btk Kinase Domain Complexed With 4-Methanesulfonyl-N-(3-{8-[4-(Morpholine-4-Carbonyl)-Phenylamino]-Imidazo[1,2-A]Pyrazin-6-Yl}-Phenyl)-Benzamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.05 Å Release Date: 2014-05-14 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 2V1 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-05-14
Ligands: 2V1
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Crystal Structure Of Btk Kinase Domain Complexed With 1-[5-[3-(7-Tert-Butyl-4-Oxo-Quinazolin-3-Yl)-2-Methyl-Phenyl]-1-Methyl-2-Oxo-3-Pyridyl]-3-Methyl-Urea
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.55 Å Release Date: 2014-05-14 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 2V2, DMS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-05-14
Ligands: 2V2, DMS
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Crystal Structure Of Btk Kinase Domain Complexed With 6-Cyclopropyl-2-[3-[5-[[5-(4-Ethylpiperazin-1-Yl)-2-Pyridyl]Amino]-1-Methyl-6-Oxo-3-Pyridyl]-2-(Hydroxymethyl)Phenyl]-8-Fluoro-Isoquinolin-1-One
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.95 Å Release Date: 2014-05-14 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 2V3, DMS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-05-14
Ligands: 2V3, DMS
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Potent And Selective Inhibitors Of Pi3K-Delta: Obtaining Isoform Selectivity From The Affinity Pocket And Tryptophan Shelf
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.67 Å Release Date: 2013-04-17 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 0SC |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-04-17
Ligands: 0SC
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Potent And Selective Inhibitors Of Pi3K-Delta: Obtaining Isoform Selectivity From The Affinity Pocket And Tryptophan Shelf
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.80 Å Release Date: 2013-04-17 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 0SD |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-04-17
Ligands: 0SD
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Potent And Selective Inhibitors Of Pi3K-Delta: Obtaining Isoform Selectivity From The Affinity Pocket And Tryptophan Shelf
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.94 Å Release Date: 2013-04-17 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 0SE |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-04-17
Ligands: 0SE
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Potent And Highly Selective Benzimidazole Inhibitors Of Pi3K-Delta
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.44 Å Release Date: 2012-08-22 Classification: transferase/transferase inhibitor Ligands: 0WR |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2012-08-22
Ligands: 0WR
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Hiv-1 Rt With Pyridone Non-Nucleoside Inhibitor
Organism: Hiv-1 m:b_hxb2r
Method: X-RAY DIFFRACTION Resolution:2.60 Å Release Date: 2009-12-15 Classification: TRANSFERASE Ligands: 3OB |
Organism: Hiv-1 m:b_hxb2r
Method: X-RAY DIFFRACTION
Release Date: 2009-12-15
Ligands: 3OB
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Hiv-1 Rt With Non-Nucleoside Inhibitor Annulated Pyrazole 1
Organism: Hiv-1 m:b_hxb2r
Method: X-RAY DIFFRACTION Resolution:2.30 Å Release Date: 2008-11-25 Classification: TRANSFERASE Ligands: PZL |
Organism: Hiv-1 m:b_hxb2r
Method: X-RAY DIFFRACTION
Release Date: 2008-11-25
Ligands: PZL
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Hiv-Rt With Non-Nucleoside Inhibitor Annulated Pyrazole 2
Organism: Human immunodeficiency virus type 1
Method: X-RAY DIFFRACTION Resolution:2.95 Å Release Date: 2008-11-25 Classification: TRANSFERASE Ligands: PZ2 |
Organism: Human immunodeficiency virus type 1
Method: X-RAY DIFFRACTION
Release Date: 2008-11-25
Ligands: PZ2
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Hiv-1 Rt With Pyridazinone Non-Nucleoside Inhibitor
Organism: Human immunodeficiency virus type 1 (hxb2 isolate)
Method: X-RAY DIFFRACTION Resolution:2.65 Å Release Date: 2008-08-19 Classification: TRANSFERASE Ligands: PDZ |
Organism: Human immunodeficiency virus type 1 (hxb2 isolate)
Method: X-RAY DIFFRACTION
Release Date: 2008-08-19
Ligands: PDZ