Search Count: 16
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Pi3K-Gamma K802T In Complex With Cpd 8 10-((1-(Tert-Butyl)Piperidin-4-Yl)Sulfinyl)-2-(1-Isopropyl-1H-1,2,4-Triazol-5-Yl)-5,6-Dihydrobenzo[F]Imidazo[1,2-D][1,4]Oxazepine
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.02 Å Release Date: 2017-11-15 Classification: TRANSFERASE/TRANSFERASE INHBITOR Ligands: BWY |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-11-15
Ligands: BWY
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Human Nav1.7-Vsd4-Navab In Complex With Gx-936.
Organism: Arcobacter butzleri, homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.53 Å Release Date: 2015-12-23 Classification: METAL TRANSPORT Ligands: PX4, 5P2 |
Organism: Arcobacter butzleri, homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-12-23
Ligands: PX4, 5P2
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Potent And Selective Inhibitors Of Pi3K-Delta: Obtaining Isoform Selectivity From The Affinity Pocket And Tryptophan Shelf
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.67 Å Release Date: 2013-04-17 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 0SC |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-04-17
Ligands: 0SC
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Potent And Selective Inhibitors Of Pi3K-Delta: Obtaining Isoform Selectivity From The Affinity Pocket And Tryptophan Shelf
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.80 Å Release Date: 2013-04-17 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 0SD |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-04-17
Ligands: 0SD
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Potent And Selective Inhibitors Of Pi3K-Delta: Obtaining Isoform Selectivity From The Affinity Pocket And Tryptophan Shelf
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.94 Å Release Date: 2013-04-17 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 0SE |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-04-17
Ligands: 0SE
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Potent And Highly Selective Benzimidazole Inhibitors Of Pi3K-Delta
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.44 Å Release Date: 2012-08-22 Classification: transferase/transferase inhibitor Ligands: 0WR |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2012-08-22
Ligands: 0WR
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Rational Design Of Pi3K-Alpha Inhibitors That Exhibit Selectivity Over The Pi3K-Beta Isoform
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.50 Å Release Date: 2011-11-16 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 3T8 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-11-16
Ligands: 3T8
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Discovery Of Gdc-0980: A Potent, Selective, And Orally Available Class I Phosphatidylinositol 3-Kinase (Pi3K)/Mammalian Target Of Rapamycin (Mtor) Kinase Inhibitor For The Treatment Of Cancer
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.79 Å Release Date: 2011-11-02 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 980 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-11-02
Ligands: 980
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Structure-Based Design Of Thienobenzoxepin Inhibitors Of Pi3- Kinase
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.50 Å Release Date: 2011-08-03 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: FAV |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-08-03
Ligands: FAV
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Structure-Based Design Of Thienobenzoxepin Inhibitors Of Pi3-Kinase
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.90 Å Release Date: 2011-08-03 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: FAZ |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-08-03
Ligands: FAZ
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Structure-Based Optimization Of Pyrazolo -Pyrimidine And -Pyridine Inhibitors Of Pi3-Kinase
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.75 Å Release Date: 2010-12-29 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: NZS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2010-12-29
Ligands: NZS
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Structure-Based Optimization Of Pyrazolo -Pyrimidine And -Pyridine Inhibitors Of Pi3-Kinase
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.60 Å Release Date: 2010-12-29 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: NZU |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2010-12-29
Ligands: NZU
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Crystal Structures Of Pan-Pi3-Kinase And Dual Pan-Pi3-Kinase/Mtor Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.00 Å Release Date: 2010-02-16 Classification: TRANSFERASE Ligands: JZW |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2010-02-16
Ligands: JZW
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Discovery Of (Thienopyrimidin-2-Yl)Aminopyrimidines As Potent, Selective, And Orally Available Pan-Pi3-Kinase And Dual Pan-Pi3-Kinase/Mtor Inhibitors For The Treatment Of Cancer
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.90 Å Release Date: 2010-02-16 Classification: TRANSFERASE Ligands: JZX |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2010-02-16
Ligands: JZX
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Discovery Of (Thienopyrimidin-2-Yl)Aminopyrimidines As Potent, Selective, And Orally Available Pan-Pi3-Kinase And Dual Pan-Pi3-Kinase/Mtor Inhibitors For The Treatment Of Cancer
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.00 Å Release Date: 2010-02-16 Classification: TRANSFERASE Ligands: JZY |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2010-02-16
Ligands: JZY
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Short Factor Viia With A Small Molecule Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.00 Å Release Date: 2005-01-18 Classification: HYDROLASE Ligands: CA, SO4, 905 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2005-01-18
Ligands: CA, SO4, 905