Search Count: 19
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Hdm2 (17-111, Wild Type) Complexed With Compound 12 At 1.8A; Structural States Of Hdm2 And Hdmx: X-Ray Elucidation Of Adaptations And Binding Interactions For Different Chemical Compound Classes
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.80 Å Release Date: 2019-05-15 Classification: LIGASE Ligands: HRE, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-05-15
Ligands: HRE, SO4
 |
Hdm2 (17-111, Wild Type) Complexed With Compound 11 At 2.0A; Structural States Of Hdm2 And Hdmx: X-Ray Elucidation Of Adaptations And Binding Interactions For Different Chemical Compound Classes
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.00 Å Release Date: 2019-05-15 Classification: LIGASE Ligands: HRH |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-05-15
Ligands: HRH
 |
Hdm2 (17-111, Wildtype) Complexed With Compound 9 At 1.13A; Structural States Of Hdm2 And Hdmx: X-Ray Elucidation Of Adaptations And Binding Interactions For Different Chemical Compound Classes
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.13 Å Release Date: 2019-05-15 Classification: LIGASE Ligands: HTZ, CL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-05-15
Ligands: HTZ, CL
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Hdm2 (17-111, Wildtype) Complexed With Compound 10 At 1.21A; Structural States Of Hdm2 And Hdmx: X-Ray Elucidation Of Adaptations And Binding Interactions For Different Chemical Compound Classes
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.21 Å Release Date: 2019-05-15 Classification: LIGASE Ligands: HU8 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-05-15
Ligands: HU8
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Hdmx (14-111; C17S) Complexed With Compound 13 At 2.1A; Structural States Of Hdm2 And Hdmx: X-Ray Elucidation Of Adaptations And Binding Interactions For Different Chemical Compound Classes
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.10 Å Release Date: 2019-05-15 Classification: APOPTOSIS Ligands: HUE, O4B, SO4, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-05-15
Ligands: HUE, O4B, SO4, GOL
 |
Hdmx (14-111; C17S) Complexed With Compound 14 At 2.4A: Structural States Of Hdm2 And Hdmx: X-Ray Elucidation Of Adaptations And Binding Interactions For Different Chemical Compound Classes
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.40 Å Release Date: 2019-05-15 Classification: APOPTOSIS Ligands: HRN, O4B, SO4, NA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-05-15
Ligands: HRN, O4B, SO4, NA
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Hdmx (14-111; C17S) Complexed With Compound 12 At 2.4A; Structural States Of Hdm2 And Hdmx: X-Ray Elucidation Of Adaptations And Binding Interactions For Different Chemical Compound Classes
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.40 Å Release Date: 2019-05-15 Classification: APOPTOSIS Ligands: HRE, O4B, CL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-05-15
Ligands: HRE, O4B, CL
 |
X-Ray Structure Of Compound 15 Bound To Hdmx: Structural States Of Hdm2 And Hdmx: X-Ray Elucidation Of Adaptations And Binding Interactions For Different Chemical Compound Classes
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.55 Å Release Date: 2019-05-15 Classification: APOPTOSIS Ligands: HRT, SO4, O4B |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-05-15
Ligands: HRT, SO4, O4B
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Hdmx (14-111; C17S) Complexed With Compound 16 At 1.20A; Structural States Of Hdm2 And Hdmx: X-Ray Elucidation Of Adaptations And Binding Interactions For Different Chemical Compound Classes
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.20 Å Release Date: 2019-05-15 Classification: APOPTOSIS Ligands: HRQ |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-05-15
Ligands: HRQ
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In Vitro And In Vivo Characterization Of A Novel, Highly Potent P53-Mdm2 Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.00 Å Release Date: 2018-09-26 Classification: CELL CYCLE Ligands: EYH, CL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-09-26
Ligands: EYH, CL
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Discovery Of A Novel Class Of Highly Potent Inhibitors Of The P53-Mdm2 Interaction By Structure-Based Design Starting From A Conformational Argument
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.58 Å Release Date: 2016-09-07 Classification: CELL CYCLE Ligands: 6ZT, SO4, CL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-09-07
Ligands: 6ZT, SO4, CL
 |
Discovery Of Nvp-Cgm097 - A Highly Potent And Selective Mdm2 Inhibitor Undergoing Phase 1 Clinical Trials In P53Wt Tumors: Hdm2 (Mdm2) Complexed With Nvp-Cgm097
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.80 Å Release Date: 2015-07-29 Classification: CELL CYCLE Ligands: 4T4, CL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-07-29
Ligands: 4T4, CL
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Discovery Of Nvp-Cgm097 - A Highly Potent And Selective Mdm2 Inhibitor Undergoing Phase 1 Clinical Trials In P53Wt Tumors: Hdm2 (Mdm2) Complexed With Cpd2
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.67 Å Release Date: 2015-07-29 Classification: CELL CYCLE Ligands: 4TH, CL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-07-29
Ligands: 4TH, CL
 |
Crystal Structure Of Renin With Inhibitor 7
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.80 Å Release Date: 2008-07-08 Classification: HYDROLASE Ligands: C40 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2008-07-08
Ligands: C40
 |
Crystal Structure Of Renin With Inhibitor 3
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.80 Å Release Date: 2008-07-08 Classification: HYDROLASE Ligands: C47 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2008-07-08
Ligands: C47
 |
Crystal Structure Of Renin With Inhibitor 10 (Aliskiren)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.20 Å Release Date: 2007-07-03 Classification: HYDROLASE Ligands: NAG, C41 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2007-07-03
Ligands: NAG, C41
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Crystal Structure Of Renin With Inhibitor 9
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.10 Å Release Date: 2007-07-03 Classification: HYDROLASE Ligands: C61 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2007-07-03
Ligands: C61
 |
Crystal Structure Of Renin With Inhibitor 6
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.10 Å Release Date: 2007-07-03 Classification: HYDROLASE Ligands: C80 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2007-07-03
Ligands: C80
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Crystal Structure Of Renin With Inhibitor 8
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.20 Å Release Date: 2007-07-03 Classification: HYDROLASE Ligands: C39 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2007-07-03
Ligands: C39