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9TF3 image
Erap1 In Complex With (3S,4S)-1-(3-Cyano-6-Methylpyridin-2-Yl)-4-(Propan-2-Yl)Pyrrolidine-3-Carboxylic Acid

9TF4 image
Erap1 In Complex With (3R,4R)-1-(3-Cyano-6-Methylpyridin-2-Yl)-4-(Propan-2-Yl)Pyrrolidine-3-Carboxylic Acid

9TF6 image
Erap1 In Complex With (3R,4R)-1-[3-Cyano-6-(Cyclopropylamino)Pyridin-2-Yl]-4-(Propan-2-Yl)Pyrrolidine-3-Carboxylic Acid

9TFN image
Erap1 In Complex With (3R,4R)-1-{3-Cyano-4-Methyl-6-[(4-Methyloxan-4-Yl)Amino]Pyridin-2-Yl}-4-(Propan-2-Yl)Pyrrolidine-3-Carboxylic Acid

9TDA image
Erap1 In Complex With 1-[2-(5-Bromo-7-Fluoro-2-Oxo-2,3-Dihydro-1,3-Benzothiazol-3-Yl)Acetamido]-4,4-Difluorocyclohexane-1-Carboxylic Acid

9TD3 image
Erap1 In Complex With 1-[2-(6-Bromo-2,2-Difluoro-3-Oxo-3,4-Dihydro-2H-1,4-Benzoxazin-4-Yl)Acetamido]Cyclohexane-1-Carboxylic Acid

9TD4 image
Erap1 In Complex With 1-[2-(2-Oxo-5-Phenyl-2,3-Dihydro-1,3-Benzoxazol-3-Yl)Acetamido]Cyclohexane-1-Carboxylic Acid

9TD5 image
Erap1 In Complex With 1-[2-(5-Chloro-2-Oxo-2,3-Dihydro-1,3-Benzothiazol-3-Yl)Acetamido]Cyclohexane-1-Carboxylic Acid

9TD7 image
Erap1 In Complex With 1-[2-(3-Oxo-6-Phenyl-3,4-Dihydro-2H-1,4-Benzoxazin-4-Yl)Acetamido]Cyclohexane-1-Carboxylic Acid

9GJN image
Erap1 In Complex With 1-[2-(3-Oxo-3,4-Dihydro-2H-1,4-Benzothiazin-4-Yl)Acetamido]Cyclohexane-1-Carboxylic Acid

9GJS image
Erap1 In Complex With 1-[2-(6-Bromo-3-Oxo-3,4-Dihydro-2H-1,4-Benzoxazin-4-Yl)Acetamido]-4,4-Difluorocyclohexane-1-Carboxylic Acid

9GK6 image
Erap1 In Complex With 1-[2-(6-Chloro-3-Oxo-3,4-Dihydro-2H-1,4-Benzothiazin-4-Yl)Acetamido]Cyclohexane-1-Carboxylic Acid

9GKE image
Erap1 In Complex With 1-[2-(2-Oxo-5-Phenyl-2,3-Dihydro-1,3-Benzothiazol-3-Yl)Acetamido]Cyclohexane-1-Carboxylic Acid

8P0I image
Crystal Structure Of The Open Conformation Of Insulin-Regulated Aminopeptidase In Complex With A Small-Mw Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:3.50 Å Release Date: 2024-09-04
Classification: HYDROLASE
Ligands: NAG, WC3, ZN

8CGP image
Insulin Regulated Aminopeptidase (Irap) In Complex With An Allosteric Aryl Sulfonamide Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:2.62 Å Release Date: 2024-01-31
Classification: HYDROLASE
Ligands: NAG, MLT, ZN, UKG, PEG, EDO

8CGW image
Insulin-Regulated Aminopeptidase (Irap) In Complex With An Allosteric Benzopyran-Based Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:3.03 Å Release Date: 2024-01-31
Classification: HYDROLASE
Ligands: ZN, UJX, NAG, PEG, EDO, GLY

7Z28 image
High-Resolution Crystal Structure Of Erap1 With Bound Bestatin Analogue Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:1.55 Å Release Date: 2022-07-27
Classification: HYDROLASE
Ligands: NAG, ZN, I88, EDO, MLT, PGE

7SH0 image
Crystal Structure Of Endoplasmic Reticulum Aminopeptidase 2 (Erap2) Complex With A Highly Selective And Potent Small Molecule

7ZYF image
Insulin Regulated Aminopeptidase (Irap) In Complex With A Nanomolar Alpha Hydroxy Beta Amino Acid Based Inhibitor.
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:2.81 Å Release Date: 2022-07-20
Classification: HYDROLASE
Ligands: ZN, NAG, KFR, EDO, PEG, TRS

7NSK image
Endoplasmic Reticulum Aminopeptidase 2 Complexed With A Hydroxamic Ligand
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:3.10 Å Release Date: 2022-06-22
Classification: HYDROLASE
Ligands: ZN, NAG, P4G, UQE, EDO
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