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Influenza Pa-N Endonuclease I38T Mutant With Compound 1 (3-Hydroxy-6-(2-Methylphenyl)-4-Oxo-1,4-Dihydropyridine-2-Carboxylic Acid)
Organism: Influenza a virus (a/california/04/2009(h1n1))
Method: X-RAY DIFFRACTION Resolution:2.49 Å Release Date: 2026-01-21 Classification: LYASE Ligands: MN, HNS |
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Influenza Pa-N Endonuclease I38T Mutant With Compound 2 ((6M)-6-(2-Ethylphenyl)-3,4-Dihydroxypyridine-2-Carboxylic Acid)
Organism: Influenza a virus (a/california/04/2009(h1n1))
Method: X-RAY DIFFRACTION Resolution:2.25 Å Release Date: 2026-01-21 Classification: LYASE Ligands: A1CI3, MN |
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Influenza Pa-N Endonuclease I38T Mutant With Compound 3 ((6M)-3-Hydroxy-6-[2-(Methylsulfanyl)Phenyl]-4-Oxo-1,4-Dihydropyridine-2-Carboxylic Acid)
Organism: Influenza a virus (a/california/04/2009(h1n1))
Method: X-RAY DIFFRACTION Resolution:2.39 Å Release Date: 2026-01-21 Classification: LYASE Ligands: MN, A1CI4 |
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Influenza Pa-N Endonuclease I38T Mutant With Compound 4 ((6M)-3-Hydroxy-4-Oxo-6-(2-Phenoxyphenyl)-1,4-Dihydropyridine-2-Carboxylic Acid)
Organism: Influenza a virus (a/california/04/2009(h1n1))
Method: X-RAY DIFFRACTION Resolution:2.36 Å Release Date: 2026-01-21 Classification: LYASE Ligands: MN, A1CI5 |
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Influenza Pa-N Endonuclease E23K Mutant With Compound 4 ((6M)-3-Hydroxy-4-Oxo-6-(2-Phenoxyphenyl)-1,4-Dihydropyridine-2-Carboxylic Acid)
Organism: Influenza a virus (a/california/04/2009(h1n1))
Method: X-RAY DIFFRACTION Resolution:2.21 Å Release Date: 2026-01-21 Classification: LYASE Ligands: MN, A1CI5 |
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Influenza Pa-N Endonuclease I38T With Compound 3 ((6M)-3-Hydroxy-6-[2-(Methylsulfanyl)Phenyl]-4-Oxo-1,4-Dihydropyridine-2-Carboxylic Acid)
Organism: Influenza a virus (a/california/04/2009(h1n1))
Method: X-RAY DIFFRACTION Resolution:2.14 Å Release Date: 2026-01-21 Classification: LYASE Ligands: MN, A1CI4 |
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Influenza Pa-N Endonuclease With Compound 4 ((6M)-3-Hydroxy-4-Oxo-6-(2-Phenoxyphenyl)-1,4-Dihydropyridine-2-Carboxylic Acid)
Organism: Influenza a virus (a/california/04/2009(h1n1))
Method: X-RAY DIFFRACTION Resolution:2.17 Å Release Date: 2026-01-21 Classification: LYASE Ligands: MN, A1CI5 |
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Organism: Influenza a virus (a/california/04/2009(h1n1))
Method: X-RAY DIFFRACTION Resolution:1.79 Å Release Date: 2024-08-28 Classification: VIRAL PROTEIN,HYDROLASE/INHIBITOR Ligands: MN, E4Z |
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Organism: Influenza a virus (a/california/04/2009(h1n1))
Method: X-RAY DIFFRACTION Resolution:1.65 Å Release Date: 2024-06-12 Classification: VIRAL PROTEIN,HYDROLASE/INHIBITOR Ligands: MN, E4Z |
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Organism: Influenza a virus
Method: X-RAY DIFFRACTION Resolution:2.03 Å Release Date: 2024-05-08 Classification: VIRAL PROTEIN,HYDROLASE Ligands: MN |
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Organism: Influenza a virus
Method: X-RAY DIFFRACTION Resolution:2.08 Å Release Date: 2024-05-08 Classification: VIRAL PROTEIN,HYDROLASE Ligands: MN |
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Influenza Pan Endonuclease I38T Mutant With 6-(4-(1H-Tetrazol-5-Yl)-2-(Trifluoromethyl)Phenyl)-3-Hydroxy-4-Oxo-1,4-Dihydropyridine-2-Carboxylic Acid
Organism: Influenza a virus
Method: X-RAY DIFFRACTION Resolution:1.91 Å Release Date: 2024-05-08 Classification: VIRAL PROTEIN,HYDROLASE/INHIBITOR Ligands: MN, IJM |
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Influenza Pan Endonuclease E23K Mutant With 6-(4-(1H-Tetrazol-5-Yl)-2-(Trifluoromethyl)Phenyl)-3-Hydroxy-4-Oxo-1,4-Dihydropyridine-2-Carboxylic Acid
Organism: Influenza a virus
Method: X-RAY DIFFRACTION Resolution:2.60 Å Release Date: 2024-05-08 Classification: VIRAL PROTEIN,HYDROLASE/INHIBITOR Ligands: MN, IJM |
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Influenza Pan Endonuclease With 6-(4-(1H-Tetrazol-5-Yl)-2-(Trifluoromethyl)Phenyl)-3-Hydroxy-4-Oxo-1,4-Dihydropyridine-2-Carboxylic Acid
Organism: Influenza a virus
Method: X-RAY DIFFRACTION Resolution:2.11 Å Release Date: 2024-05-08 Classification: VIRAL PROTEIN,HYDROLASE/INHIBITOR Ligands: MN, IJM |
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Organism: Influenza a virus (a/california/04/2009(h1n1))
Method: X-RAY DIFFRACTION Resolution:2.09 Å Release Date: 2024-02-14 Classification: HYDROLASE Ligands: MN |
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Masking Thiol Reactivity With Thioamide-Based Mbps- Carbonic Anhydrase Ii Complexed With Benzo[D]Thiazole-2(3H)-Thione
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.37 Å Release Date: 2023-03-01 Classification: LYASE Ligands: ZN, XO9, MBO, DMS |
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Masking Thiol Reactivity With Thioamide-Based Mbps- Carbonic Anhydrase Ii Complexed With 4-Phenylthiazole-2(3H)-Thione
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.44 Å Release Date: 2023-03-01 Classification: LYASE/INHIBITOR Ligands: Y3E, ZN, SO4 |
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The N-Terminal Domain Of Pa Endonuclease From The Influenza H1N1 Viral Polymerase In Complex With 6-Bromo-3-Hydroxy-4-Oxo-1,4-Dihydropyridine-2-Carboxamide
Organism: Influenza a virus (a/california/04/2009(h1n1))
Method: X-RAY DIFFRACTION Resolution:1.91 Å Release Date: 2022-12-21 Classification: VIRAL PROTEIN,HYDROLASE/INHIBITOR Ligands: MN, PQO |
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The N-Terminal Domain Of Pa Endonuclease From The Influenza H1N1 Viral Polymerase In Complex With 3-Hydroxy-4-Oxo-1,4-Dihydropyridine-2-Carboxylic Acid
Organism: Influenza a virus
Method: X-RAY DIFFRACTION Resolution:2.14 Å Release Date: 2022-12-21 Classification: VIRAL PROTEIN,HYDROLASE/INHIBITOR Ligands: ACT, Q3O, MN |
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The N-Terminal Domain Of Pa Endonuclease From The Influenza H1N1 Viral Polymerase In Complex With 4-(Benzyloxy)-6-Bromo-3-Hydroxypicolinonitrile
Organism: Influenza a virus
Method: X-RAY DIFFRACTION Resolution:2.20 Å Release Date: 2022-12-21 Classification: VIRAL PROTEIN,HYDROLASE/INHIBITOR Ligands: R6O, MN |