Search Count: 18
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Crystal Structure Of Irak4-Hsa Complexed With N-[(2R)-2-Fluoro-3-Hydroxy-3-Methylbutyl]-6-[(5-Fluoropyri-Yl)Amino]-4-[(Propan-2-Yl)Amino]Pyridine-3-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.89 Å Release Date: 2025-02-12 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: ZVD, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-02-12
Ligands: ZVD, SO4
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Crystal Structure Of Irak4-Hsa Complexed With Bms-986126; 6-((5-Cyano-2-Pyrimidinyl)Amino)-N-((2R)-2-Fluoro-3-Hydroxhylbutyl)-4-(Isopropylamino)Nicotinamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.69 Å Release Date: 2025-02-12 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: ZVG, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-02-12
Ligands: ZVG, SO4
 |
Crystal Structure Of Irak4-Hsa Complexed With Bms-986147; 6-{5-Cyano-1H-Pyrazolo[3,4-B]Pyridin-1-Yl}-N-[(2R)-2-Fluorroxy-3-Methylbutyl]-4-[(Propan-2-Yl)Amino]Pyridine-3-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.76 Å Release Date: 2025-02-12 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: SO4, ZVA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-02-12
Ligands: SO4, ZVA
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Crystal Structure Of Rar-Related Orphan Receptor C (Nhis-Rorgt(244-487)-L6-Src1(678-692)) In Complex With {3,5-Dichloro-4-[4-Methoxy-3-(Propan-2-Yl)Phenoxy]Phenyl}Methanol
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.62 Å Release Date: 2021-01-20 Classification: TRANSFERASE/Agonist Ligands: Z7G |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-01-20
Ligands: Z7G
 |
Crystal Structure Of Rar-Related Orphan Receptor C (Nhis-Rorgt(244-487)-L6-Src1(678-692)) In Complex With {3,5-Dichloro-4-[4-Methoxy-3-(Propan-2-Yl)Phenoxy]Phenyl}Methanol
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.42 Å Release Date: 2021-01-20 Classification: TRANSFERASE/Agonist Ligands: Z7H |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-01-20
Ligands: Z7H
 |
Crystal Structure Of Rar-Related Orphan Receptor C (Nhis-Rorgt(244-487)-L6-Src1(678-692)) In Complex With {3,5-Dichloro-4-[4-Methoxy-3-(Propan-2-Yl)Phenoxy]Phenyl}Methanol
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.14 Å Release Date: 2021-01-20 Classification: TRANSFERASE/Agonist Ligands: Z7I |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-01-20
Ligands: Z7I
 |
Crystal Structure Of Rar-Related Orphan Receptor C In Complex With A Novel Inverse Agonist
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.15 Å Release Date: 2020-08-12 Classification: TRANSCRIPTION/Agonist Ligands: V27 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-08-12
Ligands: V27
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Crystal Structure Of Rar-Related Orphan Receptor C In Complex With A Potent, Selective And Orally Bioavailable Ror-Gamma-T Inverse Agonist
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.37 Å Release Date: 2020-08-12 Classification: TRANSCRIPTION/AGONIST Ligands: VBG, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-08-12
Ligands: VBG, SO4
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Substituted Benzyloxytricyclic Compounds As Retinoic Acid-Related Orphan Receptor Gamma T Agonists
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.26 Å Release Date: 2020-06-17 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: Z7F |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-06-17
Ligands: Z7F
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Substituted Benzyloxytricyclic Compounds As Retinoic Acid-Related Orphan Receptor Gamma T Agonists
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.00 Å Release Date: 2020-04-29 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: TKJ |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-04-29
Ligands: TKJ
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Substituted Benzyloxytricyclic Compounds As Retinoic Acid-Related Orphan Receptor Gamma T Agonists
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.61 Å Release Date: 2020-04-29 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: Z7D |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-04-29
Ligands: Z7D
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Structure Of Human Pregnane X Receptor Ligand Binding Domain Bound Tethered With Src Co-Activator Peptide And Compound-3 Aka 1,1,1,3,3,3-Hexafluoro-2-{4-[1-(4- Luorobenzenesulfonyl)Cyclopentyl]Phenyl}Propan-2-Ol
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.27 Å Release Date: 2020-02-12 Classification: TRANSFERASE Ligands: L7D |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-02-12
Ligands: L7D
 |
Crystal Structure Of Jak3 Kinase Domain In Complex With A Pyrrolopyridazine Carboxamide Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.33 Å Release Date: 2019-05-22 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: Z3A |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-05-22
Ligands: Z3A
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Crystal Structure Of Rar-Related Orphan Receptor C In Complex With A Phenyl (3-Phenylpyrrolidin-3-Yl)Sulfone Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.29 Å Release Date: 2019-03-20 Classification: TRANSCRIPTION/INHIBITOR Ligands: L8A |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-03-20
Ligands: L8A
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Crystal Structure Of Myeloperoxidase Subform C (Mpo) Complex With Compound-6 Aka 7-(Benzyloxy)-1H-[1,2, 3]Triazolo[4,5-D]Pyrimidin-5-Amine
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.40 Å Release Date: 2018-04-18 Classification: METAL BINDING PROTEIN Ligands: AEY, CL, HEM, CA, NAG, FUC, MAN |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-04-18
Ligands: AEY, CL, HEM, CA, NAG, FUC, MAN
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Identification Of Bicyclic Hexafluoroisopropyl Alcohol Sulfonamides As Rorgt/Rorc Inverse Agonists
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.40 Å Release Date: 2017-12-20 Classification: TRANSCRIPTION/TRANSCRIPTION INHIBITOR Ligands: XGH, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-12-20
Ligands: XGH, SO4
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Structure Of Human Pregnane X Receptor Ligand Binding Domain Bound Tethered With Src Co-Activator Peptide And Compound 25A Aka Bicyclic Hexafluoroisopropyl 2 Alcohol Sulfonamides
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.56 Å Release Date: 2017-12-20 Classification: NUCLEAR PROTEIN Ligands: XGH |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-12-20
Ligands: XGH
 |
Crystal Structure Of Jak3 Kinase Domain In Complex With A Pyrrolopyridazine Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.65 Å Release Date: 2017-05-31 Classification: TRANSFERASE/INHIBITOR Ligands: 9J4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-05-31
Ligands: 9J4