Search Count: 32
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Crystal Structure Of Polo Box Domain In Complex With Cyclic Peptide Inhibitor
Organism: Homo sapiens, Synthetic construct
Method: X-RAY DIFFRACTION Resolution:1.85 Å Release Date: 2022-03-02 Classification: TRANSFERASE/Inhibitor |
Organism: Homo sapiens, Synthetic construct
Method: X-RAY DIFFRACTION
Release Date: 2022-03-02
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Crystal Structure Of The First Bromodomain Of Human Brd4 In Complex With The Inhibitor Jwg056
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.47 Å Release Date: 2019-03-06 Classification: TRANSCRIPTION/INHIBITOR Ligands: X27 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-03-06
Ligands: X27
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Src Kinase Bound To Covalent Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.40 Å Release Date: 2019-02-27 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 6H3 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-02-27
Ligands: 6H3
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Crystal Structure Of Erk2 Covalently Bound To Sm1-71
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.05 Å Release Date: 2019-02-27 Classification: TRANSFERASE Ligands: SO4, 6H3, EDO, CL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-02-27
Ligands: SO4, 6H3, EDO, CL
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Crystal Structure Of Erk1 Covalently Bound To Sm1-71
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.07 Å Release Date: 2019-02-27 Classification: TRANSFERASE Ligands: 6H3, EWH, SO4, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-02-27
Ligands: 6H3, EWH, SO4, EDO
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Crystal Structure Of The First Bromodomain Of Human Brd4 In Complex With The Inhibitor Xmd17-26
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.58 Å Release Date: 2019-01-16 Classification: TRANSCRIPTION/INHIBITOR Ligands: R4L, EDO, NO3 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-01-16
Ligands: R4L, EDO, NO3
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Crystal Structure Of Ack1 With Compound 10D
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.20 Å Release Date: 2018-09-26 Classification: TRANSFERASE Ligands: 9KO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-09-26
Ligands: 9KO
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Crystal Structure Of The First Bromodomain Of Human Brd4 In Complex With The Inhibitor Jwg046
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.23 Å Release Date: 2018-08-29 Classification: TRANSCRIPTION/INHIBITOR Ligands: EX1, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-08-29
Ligands: EX1, EDO
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Crystal Structure Of The First Bromodomain Of Human Brd4 In Complex With The Inhibitor Jwg047
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.51 Å Release Date: 2018-08-29 Classification: TRANSCRIPTION/INHIBITOR Ligands: X26, EDO, NO3 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-08-29
Ligands: X26, EDO, NO3
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Crystal Structure Of The First Bromodomain Of Human Brd4 In Complex With The Inhibitor Jwg069
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.68 Å Release Date: 2018-08-29 Classification: TRANSCRIPTION/INHIBITOR Ligands: F3J, EDO, NO3 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-08-29
Ligands: F3J, EDO, NO3
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Crystal Structure Of The First Bromodomain Of Human Brd4 In Complex With The Inhibitor Jwg071
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.53 Å Release Date: 2018-08-29 Classification: TRANSCRIPTION/INHIBITOR Ligands: F2S, FND, EDO, NO3 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-08-29
Ligands: F2S, FND, EDO, NO3
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Crystal Structure Of The First Bromodomain Of Human Brd4 In Complex With The Inhibitor Xmd11-50
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.17 Å Release Date: 2018-07-04 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 4K4, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-07-04
Ligands: 4K4, EDO
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Crystal Structure Of Aurora-A In Complex With Fmf-03-145-1 (Compound 2)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.60 Å Release Date: 2017-09-06 Classification: TRANSFERASE Ligands: 9YQ |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-09-06
Ligands: 9YQ
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Covalent Gtp-Competitive Inhibitors Of Kras G12C: Guanosine Bisphosphonate Analogs
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.70 Å Release Date: 2017-04-12 Classification: HYDROLASE/HYDROLASE inhibitor Ligands: 6ZD |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-04-12
Ligands: 6ZD
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Crystal Structure Of Egfr 696-1022 L858R In Complex With Fiin-3
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.00 Å Release Date: 2014-11-12 Classification: TRANSFERASE Ligands: FI3 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-11-12
Ligands: FI3
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Crystal Structure Of Fgf Receptor (Fgfr) 4 Kinase Domain In Complex With Fiin-2, An Irreversible Tyrosine Kinase Inhibitor Capable Of Overcoming Fgfr Kinase Gate-Keeper Mutations
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.40 Å Release Date: 2014-10-29 Classification: Transferase/transferase inhibitor Ligands: 37O, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-10-29
Ligands: 37O, SO4
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Crystal Structure Of Fgf Receptor (Fgfr) 4 Kinase Harboring The V550L Gate-Keeper Mutation In Complex With Fiin-3, An Irreversible Tyrosine Kinase Inhibitor Capable Of Overcoming Fgfr Kinase Gate-Keeper Mutations
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.35 Å Release Date: 2014-10-29 Classification: Transferase/transferase inhibitor Ligands: FI3, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-10-29
Ligands: FI3, SO4
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Crystal Structure Of Type Ii Inhibitor Ng25 Bound To Tak1-Tab1
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.39 Å Release Date: 2014-07-30 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: NG2 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-07-30
Ligands: NG2
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Discovery Of A Small Molecule Type Ii Inhibitor Of Wild-Type And Gatekeeper Mutants Of Bcr-Abl, Pdgfralpha, Kit, And Src Kinases
Organism: Gallus gallus
Method: X-RAY DIFFRACTION Resolution:2.60 Å Release Date: 2012-02-15 Classification: TRANSFERASE Ligands: NG7, MES, GOL |
Organism: Gallus gallus
Method: X-RAY DIFFRACTION
Release Date: 2012-02-15
Ligands: NG7, MES, GOL
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Discovery Of Potent And Selective Covalent Inhibitors Of Jnk
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.60 Å Release Date: 2012-02-01 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: CQQ |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2012-02-01
Ligands: CQQ