Search Count: 70
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Fgfr2 Kinase Domain Bound To Reversible Inhibitor Cmpd 3
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.24 Å Release Date: 2024-02-14 Classification: ONCOPROTEIN Ligands: GOL, GSH, WXQ |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-02-14
Ligands: GOL, GSH, WXQ
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Fgfr2 Kinase Domain Bound To Irreversible Inhibitor Cmpd 10
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.33 Å Release Date: 2024-02-14 Classification: Transferase/Inhibitor Ligands: GOL, UIM, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-02-14
Ligands: GOL, UIM, SO4
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Human Pi3K P85Alpha/P110Alpha
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.71 Å Release Date: 2023-11-22 Classification: SIGNALING PROTEIN |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-11-22
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P85Alpha/P110Alpha Heterodimer H1047R Mutant
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.72 Å Release Date: 2023-11-22 Classification: SIGNALING PROTEIN |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-11-22
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Human Pi3K P85Alpha/P110Alpha H1047R Bound To Compound 1
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.83 Å Release Date: 2023-11-22 Classification: SIGNALING PROTEIN/INHIBITOR Ligands: UE9 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-11-22
Ligands: UE9
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Human Pi3K P85Alpha/P110Alpha H1047R Bound To Compound 2
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.51 Å Release Date: 2023-11-22 Classification: SIGNALING PROTEIN/INHIBITOR Ligands: UIW |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-11-22
Ligands: UIW
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Human Pi3K P85Alpha/P110Alpha Bound To Compound 2
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.53 Å Release Date: 2023-11-22 Classification: SIGNALING PROTEIN/INHIBITOR Ligands: UIW |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-11-22
Ligands: UIW
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Human Pi3K P85Alpha/P110Alpha H1047R Bound To Compound 3
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.62 Å Release Date: 2023-11-22 Classification: SIGNALING PROTEIN/INHIBITOR Ligands: UJC |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-11-22
Ligands: UJC
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Human Pi3K P85Alpha/P110Alpha Bound To Rly-2608
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.70 Å Release Date: 2023-11-22 Classification: SIGNALING PROTEIN,TRANSFERASE/INHIBITOR Ligands: XUZ |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-11-22
Ligands: XUZ
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Cryoem Structure Of Pi3Kalpha
Organism: Homo sapiens
Method: ELECTRON MICROSCOPY Release Date: 2023-11-15 Classification: CYTOSOLIC PROTEIN |
Organism: Homo sapiens
Method: ELECTRON MICROSCOPY
Release Date: 2023-11-15
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Crystal Structure Of Human Nischarin Px And Lrr Domains With Engineered Mutations
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.56 Å Release Date: 2023-10-25 Classification: ENDOCYTOSIS Ligands: IMD |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-10-25
Ligands: IMD
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Identification Of Gdc-1971 (Rly-1971), A Shp2 Inhibitor Designed For The Treatment Of Solid Tumors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.40 Å Release Date: 2023-10-11 Classification: HYDROLASE Ligands: SO4, YR2 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-10-11
Ligands: SO4, YR2
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Identification Of Gdc-1971 (Rly-1971), A Shp2 Inhibitor Designed For The Treatment Of Solid Tumors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.84 Å Release Date: 2023-10-11 Classification: HYDROLASE Ligands: SO4, YT2 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-10-11
Ligands: SO4, YT2
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Identification Of Gdc-1971 (Rly-1971), A Shp2 Inhibitor Designed For The Treatment Of Solid Tumors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.10 Å Release Date: 2023-10-11 Classification: HYDROLASE Ligands: ZH5 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-10-11
Ligands: ZH5
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Identification Of Gdc-1971 (Rly-1971), A Shp2 Inhibitor Designed For The Treatment Of Solid Tumors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.27 Å Release Date: 2023-10-11 Classification: HYDROLASE/INHIBITOR Ligands: ZJX |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-10-11
Ligands: ZJX
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Discovery And Clinical Validation Of Rly-4008, The First Highly Selective Fgfr2 Inhibitor With Activity Across Fgfr2 Alterations And Resistance Mutations
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.79 Å Release Date: 2023-06-07 Classification: TRANSFERASE/INHIBITOR Ligands: WCJ |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-06-07
Ligands: WCJ
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Wildtype Ptp1B In Complex With Des4799
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.45 Å Release Date: 2023-04-26 Classification: HYDROLASE Ligands: YW9, MG, CL, DMS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-04-26
Ligands: YW9, MG, CL, DMS
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Wildtype Ptp1B In Complex With Des4884
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.53 Å Release Date: 2023-04-26 Classification: HYDROLASE Ligands: KB8, MG, DMS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-04-26
Ligands: KB8, MG, DMS
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Wildtype Ptp1B In Complex With Des5742
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.82 Å Release Date: 2023-04-26 Classification: HYDROLASE Ligands: YXF |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-04-26
Ligands: YXF
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Wildtype Ptp1B In Complex With Des5743
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.53 Å Release Date: 2023-04-26 Classification: HYDROLASE Ligands: YXN, MG, MPD |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-04-26
Ligands: YXN, MG, MPD