Search Count: 30
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P38 In Complex With T-3220137
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.50 Å Release Date: 2019-11-20 Classification: TRANSFERASE/INHIBITOR Ligands: MKP |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-11-20
Ligands: MKP
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Identification Of Novel, Potent And Selective Gcn2 Inhibitors As First-In-Class Anti-Tumor Agents
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.61 Å Release Date: 2019-10-09 Classification: transferase/transferase inhibitor Ligands: KAV |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-10-09
Ligands: KAV
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Identification Of Novel, Potent And Selective Gcn2 Inhibitors As First-In-Class Anti-Tumor Agents
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.01 Å Release Date: 2019-10-09 Classification: transferase/transferase inhibitor Ligands: KA4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-10-09
Ligands: KA4
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Identification Of Novel, Potent And Selective Gcn2 Inhibitors As First-In-Class Anti-Tumor Agents
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.40 Å Release Date: 2019-10-09 Classification: transferase/transferase inhibitor Ligands: KA7 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-10-09
Ligands: KA7
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Structure-Based Design, Synthesis, And Biological Evaluation Of Imidazo[4,5-B]Pyridine-2-One Based P38 Map Kinase Inhibitors By Scaffold Hopping: Compound 1
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.80 Å Release Date: 2019-04-17 Classification: TRANSFERASE Ligands: J8S |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-04-17
Ligands: J8S
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Structure-Based Design, Synthesis, And Biological Evaluation Of Imidazo[4,5-B]Pyridine-2-One Based P38 Map Kinase Inhibitors By Scaffold Hopping - Compound 10
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.45 Å Release Date: 2019-04-17 Classification: TRANSFERASE/INHIBITOR Ligands: J9G |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-04-17
Ligands: J9G
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Structure Of Rorgt In Complex With A Novel Inverse Agonist 3
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.48 Å Release Date: 2018-11-21 Classification: signaling protein/antagonist Ligands: CF7 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-11-21
Ligands: CF7
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Structure Of Rorgt In Complex With A Novel Inverse Agonist 2
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.18 Å Release Date: 2018-08-01 Classification: signaling protein/agonist Ligands: CFJ |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-08-01
Ligands: CFJ
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Structure Of Rorgt In Complex With A Novel Isoquinoline Inverse Agonist.
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.18 Å Release Date: 2018-03-21 Classification: transcription/agonist Ligands: MPD, E3S |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-03-21
Ligands: MPD, E3S
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Structure Of Rorgt In Complex With A Novel Inverse Agonist Tak-828.
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.00 Å Release Date: 2018-03-21 Classification: transcription/agonist Ligands: MPD, E3V |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-03-21
Ligands: MPD, E3V
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Structure-Based Design, Synthesis, And Biological Evaluation Of Imidazo[1,2-B]Pyridazine-Based P38 Map Kinase Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.60 Å Release Date: 2018-01-17 Classification: Transferase/Transferase Inhibitor Ligands: AQY |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-01-17
Ligands: AQY
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Structure-Based Design, Synthesis, And Biological Evaluation Of Imidazo[1,2-B]Pyridazine-Based P38 Map Kinase Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.00 Å Release Date: 2018-01-17 Classification: TRANSFERASE Ligands: T75 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-01-17
Ligands: T75
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Design, Synthesis, And Evaluation Of The First Selective And Potent G-Protein-Coupled Receptor Kinase 2 (Grk2) Inhibitor For The Potential Treatment Of Heart Failure
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.70 Å Release Date: 2017-07-26 Classification: Transferase/Transferase Inhibitor Ligands: QRW, SO4, MES |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-07-26
Ligands: QRW, SO4, MES
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Design, Synthesis, And Evaluation Of The First Selective And Potent G-Protein-Coupled Receptor Kinase 2 (Grk2) Inhibitor For The Potential Treatment Of Heart Failure
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.65 Å Release Date: 2017-07-26 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 8PV, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-07-26
Ligands: 8PV, SO4
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Human Givd Cytosolic Phospholipase A2 In Complex With Methyl Gamma-Linolenyl Fluorophosphonate
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.65 Å Release Date: 2016-06-08 Classification: HYDROLASE/HYDROLASE inhibitor Ligands: 7FA, BA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-06-08
Ligands: 7FA, BA
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Human Givd Cytosolic Phospholipase A2
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.20 Å Release Date: 2016-06-08 Classification: HYDROLASE Ligands: SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-06-08
Ligands: SO4
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Human Givd Cytosolic Phospholipase A2 In Complex With Methyl Gamma-Linolenyl Fluorophosphonate Inhibitor And Terbium Chloride
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.25 Å Release Date: 2016-06-08 Classification: HYDROLASE/HYDROLASE inhibitor Ligands: 7FA, TB |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-06-08
Ligands: 7FA, TB
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Structure Of Protein Kinase C Theta With Compound 10: 2,2-Dimethyl-7-(2-Oxidanylidene-3~{H}-Imidazo[4,5-B]Pyridin-1-Yl)-1-(Phenylmethyl)-3~{H}-Quinazolin-4-One
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.00 Å Release Date: 2016-05-11 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 5VS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-05-11
Ligands: 5VS
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Crystal Structure Of Human Integral Membrane Stearoyl-Coa Desaturase With Substrate
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.25 Å Release Date: 2015-06-17 Classification: OXIDOREDUCTASE Ligands: ZN, ST9, LMT |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-06-17
Ligands: ZN, ST9, LMT
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Crystal Structure Of Human Kinase Domain Of B-Raf With A Dfg-Out Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.95 Å Release Date: 2014-01-08 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 0T2 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-01-08
Ligands: 0T2