Search Count: 18
 |
Gdc-9545 In Complex With Estrogen Receptor Alpha
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.24 Å Release Date: 2021-06-02 Classification: TRANSCRIPTION Ligands: G9J, ZNM |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-06-02
Ligands: G9J, ZNM
 |
Crystal Structure Of Estrogen Receptor Alpha In Complex With Receptor Degrader 6
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.31 Å Release Date: 2020-07-01 Classification: NUCLEAR PROTEIN Ligands: G9J, U6D |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-07-01
Ligands: G9J, U6D
 |
Crystal Structure Of Estrogen Receptor Alpha In Complex With Receptor Degrader 16Ab
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.50 Å Release Date: 2019-02-20 Classification: NUCLEAR PROTEIN Ligands: G8Y, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-02-20
Ligands: G8Y, GOL
 |
Crystal Structure Of Estrogen Receptor Alpha In Complex With Receptor Degrader 16Aa
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.10 Å Release Date: 2019-02-20 Classification: NUCLEAR PROTEIN Ligands: G9J, NI, G91, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-02-20
Ligands: G9J, NI, G91, GOL
 |
Identification Of An Imidazopyridine Scaffold To Generate Potent And Selective Tyk2 Inhibitors That Demonstrate Activity In An In Vivo Psoriasis Model
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.45 Å Release Date: 2017-09-06 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 9ZS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-09-06
Ligands: 9ZS
 |
Identification Of An Imidazopyridine Scaffold To Generate Potent And Selective Tyk2 Inhibitors That Demonstrate Activity In An In Vivo Psoriasis Model
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.85 Å Release Date: 2017-09-06 Classification: Transferase/Transferase Inhibitor Ligands: 9ZS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-09-06
Ligands: 9ZS
 |
Map4K4 In Complex With Inhibitor Gne-495
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.89 Å Release Date: 2015-09-02 Classification: Transferase/Transferase Inhibitor Ligands: MG, MES, 4P4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-09-02
Ligands: MG, MES, 4P4
 |
Map4K4 In Complex With Inhibitor (Compound 22), 6-(3-Chlorophenyl)Quinazolin-4-Amine
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.10 Å Release Date: 2014-04-23 Classification: transferase/transferase inhibitor Ligands: MES, NA, 2QV |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-04-23
Ligands: MES, NA, 2QV
 |
Map4K4 In Complex With Inhibitor (Compound 29), 6-(2-Fluoropyridin-4-Yl)Pyrido[3,2-D]Pyrimidin-4-Amine
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.27 Å Release Date: 2014-04-23 Classification: transferase/transferase inhibitor Ligands: MG, MES, 2QU |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-04-23
Ligands: MG, MES, 2QU
 |
Map4K4 In Complex With Inhibitor (Compound 31), N-[3-(4-Aminoquinazolin-6-Yl)-5-Fluorophenyl]-2-(Pyrrolidin-1-Yl)Acetamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.19 Å Release Date: 2014-04-23 Classification: transferase/transferase inhibitor Ligands: MES, MG, 2QT |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-04-23
Ligands: MES, MG, 2QT
 |
Tyk2 (Jh1) In Complex With Adenosine Di-Phosphate
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.03 Å Release Date: 2013-08-14 Classification: HYDROLASE Ligands: ADP, MG |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-08-14
Ligands: ADP, MG
 |
Jak2 Kinase (Jh1 Domain) With 2,6-Dichloro-N-(2-Oxo-2,5-Dihydropyridin-4-Yl)Benzamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.30 Å Release Date: 2013-06-19 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 0X2 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-06-19
Ligands: 0X2
 |
Tyk2 Kinase (Jh1 Domain) With 2,6-Dichloro-N-(2-Oxo-2,5-Dihydropyridin-4-Yl)Benzamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.30 Å Release Date: 2013-06-19 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: SO4, EDO, GOL, 0X2 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-06-19
Ligands: SO4, EDO, GOL, 0X2
 |
Tyk2 (Jh1) In Complex With 2,6-Dichloro-N-{2-[(Cyclopropylcarbonyl)Amino]Pyridin-4-Yl}Benzamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.00 Å Release Date: 2013-06-19 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 0X5 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-06-19
Ligands: 0X5
 |
Jak2 Kinase (Jh1 Domain) In Complex With 2,6-Dichloro-N-{2-[(Cyclopropylcarbonyl)Amino]Pyridin-4-Yl}Benzamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.40 Å Release Date: 2013-06-19 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 0X5 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-06-19
Ligands: 0X5
 |
Tyk2 (Jh1) In Complex With 2,6-Dichloro-4-Cyano-N-{2-[(Cyclopropylcarbonyl)Amino]Pyridin-4-Yl}Benzamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.31 Å Release Date: 2013-05-29 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 0X6 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-05-29
Ligands: 0X6
 |
Tyk2 (Jh1) In Complex With 2,6-Dichloro-N-[2-({[(1R,2R)-2-Fluorocyclopropyl]Carbonyl}Amino)Pyridin-4-Yl]Benzamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.40 Å Release Date: 2013-05-29 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 0XH |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-05-29
Ligands: 0XH
 |
Tyk2 (Jh1) In Complex With 2,6-Dichloro-4-Cyano-N-[2-({[(1R,2R)-2-Fluorocyclopropyl]Carbonyl}Amino)Pyridin-4-Yl]Benzamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.50 Å Release Date: 2013-05-29 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 0XP |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-05-29
Ligands: 0XP