Search Count: 17
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Crystal Structure Of Human Mitochondrial Isocitrate Dehydrogenase (Idh2) R140Q Mutant Homodimer In Complex With Ag-221 (Enasidenib) Inhibitor.
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.55 Å Release Date: 2017-03-08 Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR Ligands: CA, GOL, NDP, NA, ACT, 69Q |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-03-08
Ligands: CA, GOL, NDP, NA, ACT, 69Q
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Crystal Structure Of Human Mitochondrial Isocitrate Dehydrogenase R140Q Mutant Homodimer Bound To Nadph And Alpha-Ketoglutaric Acid
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.54 Å Release Date: 2017-03-01 Classification: OXIDOREDUCTASE Ligands: NDP, CA, GOL, ACT, AKG |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-03-01
Ligands: NDP, CA, GOL, ACT, AKG
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Discovery Of Vx-509 (Decernotinib): A Potent And Selective Janus Kinase (Jak) 3 Inhibitor For The Treatment Of Autoimmune Disease
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.16 Å Release Date: 2015-08-12 Classification: Transferase/Transferase Inhibitor Ligands: 4HW |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-08-12
Ligands: 4HW
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Discovery Of Vx-509 (Decernotinib): A Potent And Selective Janus Kinase (Jak) 3 Inhibitor For The Treatment Of Autoimmune Diseases
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.78 Å Release Date: 2015-08-12 Classification: Transferase/Transferase Inhibitor Ligands: 4HZ |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-08-12
Ligands: 4HZ
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Discovery Of Vx-509 (Decernotinib): A Potent And Selective Janus Kinase (Jak) 3 Inhibitor For The Treatment Of Autoimmune Diseases
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.04 Å Release Date: 2015-08-12 Classification: Transferase/Transferase Inhibitor Ligands: 467 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-08-12
Ligands: 467
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Discovery Of Vx-509 (Decernotinib): A Potent And Selective Janus Kinase (Jak) 3 Inhibitor For The Treatment Of Autoimmune Disease
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.52 Å Release Date: 2015-08-12 Classification: Transferase/Transferase Inhibitor Ligands: VJK |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-08-12
Ligands: VJK
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Influenza Polymerase Basic Protein 2 (Pb2) Bound To 7-Methyl-Gtp
Organism: Influenza a virus
Method: X-RAY DIFFRACTION Resolution:2.30 Å Release Date: 2014-07-30 Classification: TRANSCRIPTION/TRANSCRIPTION INHIBITOR Ligands: MGT, 11H |
Organism: Influenza a virus
Method: X-RAY DIFFRACTION
Release Date: 2014-07-30
Ligands: MGT, 11H
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Influenza Polymerase Basic Protein 2 (Pb2) Bound To A Small-Molecule Inhibitor
Organism: Influenza a virus
Method: X-RAY DIFFRACTION Resolution:2.82 Å Release Date: 2014-07-30 Classification: TRANSCRIPTION/TRANSCRIPTION INHIBITOR Ligands: 704 |
Organism: Influenza a virus
Method: X-RAY DIFFRACTION
Release Date: 2014-07-30
Ligands: 704
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Influenza A (Flu) Virus Polymerase Basic Protein 2 (Pb2) Bound To Vx787, An Azaindole Inhibitor
Organism: Influenza a virus
Method: X-RAY DIFFRACTION Resolution:2.52 Å Release Date: 2014-07-30 Classification: transferase/transferase inhibitor Ligands: 21G |
Organism: Influenza a virus
Method: X-RAY DIFFRACTION
Release Date: 2014-07-30
Ligands: 21G
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Complex Of Mitochondrial Isocitrate Dehydrogenase R140Q Mutant With Agi-6780 Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.55 Å Release Date: 2013-04-10 Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR Ligands: NDP, 1K9, CA, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-04-10
Ligands: NDP, 1K9, CA, GOL
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Pkm2 In Complex With An Activator
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.30 Å Release Date: 2012-10-10 Classification: Transferase/Activator Ligands: OXL, MG, NZT |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2012-10-10
Ligands: OXL, MG, NZT
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Activator-Bound Structure Of Human Pyruvate Kinase M2
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.10 Å Release Date: 2012-09-12 Classification: transferase/transferase activator Ligands: FBP, UNX, 07T |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2012-09-12
Ligands: FBP, UNX, 07T
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Activator-Bound Structure Of Human Pyruvate Kinase M2
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.95 Å Release Date: 2010-04-28 Classification: TRANSFERASE Ligands: 3SZ, FBP, SO4, UNX |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2010-04-28
Ligands: 3SZ, FBP, SO4, UNX
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Janus Kinase 2 Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.10 Å Release Date: 2009-12-01 Classification: TRANSFERASE Ligands: JZH, NA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2009-12-01
Ligands: JZH, NA
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2-Aminopyrazolo[1,5-A]Pyrimidines As Potent And Selective Inhibitors Of Jak2
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.60 Å Release Date: 2009-11-10 Classification: TRANSFERASE Ligands: 1P5 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2009-11-10
Ligands: 1P5
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2-Aminopyrazolo[1,5-A]Pyrimidines As Potent And Selective Inhibitors Of Jak2
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.10 Å Release Date: 2009-11-10 Classification: TRANSFERASE Ligands: 1P6 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2009-11-10
Ligands: 1P6
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Discovery And Sar Of Novel 4-Thiazolyl-2-Phenylaminopyrimidines As Potent Inhibitors Of Spleen Tyrosine Kinase (Syk)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.60 Å Release Date: 2008-12-02 Classification: TRANSFERASE Ligands: 685 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2008-12-02
Ligands: 685