Search Count: 26
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Hpk1 Kinase Domain T165E,S171E Phosphomimetic Mutant In Complex With Compound 6
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.69 Å Release Date: 2024-12-18 Classification: TRANSFERASE Ligands: A1A1E |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-12-18
Ligands: A1A1E
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Hpk1 Kinase Domain T165E,S171E Phosphomimetic Mutant In Complex With Compound 9
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.85 Å Release Date: 2024-12-18 Classification: TRANSFERASE Ligands: SO4, A1A1D |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-12-18
Ligands: SO4, A1A1D
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Hpk1 Kinase Domain T165E,S171E Phosphomimetic Mutant In Complex With Compound 13
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.59 Å Release Date: 2024-12-18 Classification: TRANSFERASE Ligands: A1A1C |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-12-18
Ligands: A1A1C
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Hpk1 Kinase Domain T165E,S171E Phosphomimetic Mutant In Complex With Compound 21
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.46 Å Release Date: 2024-12-18 Classification: TRANSFERASE Ligands: A1A1B, CL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-12-18
Ligands: A1A1B, CL
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Hpk1 Kinase Domain T165E,S171E Phosphomimetic Mutant In Complex With Compound 53
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.95 Å Release Date: 2024-12-18 Classification: TRANSFERASE Ligands: A1A1A |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-12-18
Ligands: A1A1A
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Crystal Structure Of The Egfr Kinase Domain (L858R, T790M, V948R) In Complex With A Covalent Inhibitor N-[(3R,4R)-4-Fluoro-1-{6-[(1-Methyl-1H-Pyrazol-4-Yl)Amino]-9-(Propan-2-Yl)-9H-Purin-2-Yl}Pyrrolidin-3-Yl]Propanamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.46 Å Release Date: 2017-03-22 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 8BP, SO4, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-03-22
Ligands: 8BP, SO4, GOL
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Crystal Structure Of The Egfr Kinase Domain (L858R, T790M, V948R) In Complex With A Covalent Inhibitor N-[(3R,4R)-4-Fluoro-1-{6-[(3-Methoxy-1-Methyl-1H-Pyrazol-4-Yl)Amino]-9-(Propan-2-Yl)-9H-Purin-2-Yl}Pyrrolidin-3-Yl]Propanamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.33 Å Release Date: 2017-03-22 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 8AM, SO4, GOL, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-03-22
Ligands: 8AM, SO4, GOL, EDO
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Crystal Structure Of The Egfr Kinase Domain (L858R, T790M, V948R) In Complex With 4-(4-{[2-{[(3S)-1-Acetylpyrrolidin-3-Yl]Amino}-9-(Propan-2-Yl)-9H-Purin-6-Yl]Amino}Phenyl)-1-Methylpiperazin-1-Ium
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.82 Å Release Date: 2017-03-22 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 8BM, SO4, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-03-22
Ligands: 8BM, SO4, GOL
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Crystal Structure Of The Egfr Kinase Domain In Complex With 4-(4-{[2-{[(3S)-1-Acetylpyrrolidin-3-Yl]Amino}-9-(Propan-2-Yl)-9H-Purin-6-Yl]Amino}Phenyl)-1-Methylpiperazin-1-Ium
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.53 Å Release Date: 2017-03-22 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 8BM |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-03-22
Ligands: 8BM
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Crystal Structure Of The Egfr Kinase Domain (L858R, T790M, V948R) In Complex With A Covalent Inhibitor N-[(3R,4R)-4-Fluoro-1-{6-[(3-Methoxy-1-Methyl-1H-Pyrazol-4-Yl)Amino]-9-Methyl-9H-Purin-2-Yl}Pyrrolidin-3-Yl]Propanamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.58 Å Release Date: 2017-03-22 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 8BS, SO4, GOL, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-03-22
Ligands: 8BS, SO4, GOL, EDO
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Structure Of Human Anaplastic Lymphoma Kinase In Complex With 2-[(1R)-1-{[2-Amino-5-(1,3-Dimethyl-1H-Pyrazol-4-Yl)Pyridin-3-Yl]Oxy}Ethyl]-4-Fluoro-N,N-Dimethylbenzamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.30 Å Release Date: 2016-08-17 Classification: Transferase/Transferase Inhibitor Ligands: 6YL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-08-17
Ligands: 6YL
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Structure Of The Human Anaplastic Lymphoma Kinase In Complex With Pf- 06463922 ((10R)-7-Amino-12-Fluoro-2,10,16-Trimethyl-15-Oxo-10,15,16, 17-Tetrahydro-2H-8,4-(Metheno)Pyrazolo(4,3-H)(2,5,11) Benzoxadiazacyclotetradecine-3-Carbonitrile).
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.05 Å Release Date: 2014-05-28 Classification: TRANSFERASE Ligands: 5P8 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-05-28
Ligands: 5P8
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Structure Of L1196M Mutant Human Anaplastic Lymphoma Kinase In Complex With Pf-06463922 ((10R)-7-Amino-12-Fluoro-2,10,16-Trimethyl- 15-Oxo-10,15,16,17-Tetrahydro-2H-8,4-(Metheno)Pyrazolo(4,3-H)(2,5,11) Benzoxadiazacyclotetradecine-3-Carbonitrile).
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.66 Å Release Date: 2014-05-28 Classification: TRANSFERASE Ligands: 5P8 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-05-28
Ligands: 5P8
 |
Structure Of The Human Anaplastic Lymphoma Kinase In Complex With The Inhibitor 2-((1R)-1-((3-Amino-6-(2-Methoxypyridin-3-Yl)Pyrazin-2-Yl) Oxy)Ethyl)-4-Fluoro-N-Methylbenzamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.05 Å Release Date: 2014-05-28 Classification: TRANSFERASE Ligands: YPW |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-05-28
Ligands: YPW
 |
Structure Of The Human Anaplastic Lymphoma Kinase In Complex With The Inhibitor 3-((1R)-1-(5-Fluoro-2-(2H-1,2,3-Triazol-2-Yl)Phenyl)Ethoxy)- 5-(3-(Methylsulfonyl)Phenyl)Pyridin-2-Amine
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.73 Å Release Date: 2014-05-28 Classification: TRANSFERASE Ligands: GWH |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-05-28
Ligands: GWH
 |
Structure Of The Human Anaplastic Lymphoma Kinase In Complex With The Inhibitor (10R)-7-Amino-12-Fluoro-1,3,10,16-Tetramethyl-16,17-Dihydro- 1H-8,4-(Metheno)Pyrazolo(4,3-H)(2,5,11)Benzoxadiazacyclotetradecin-15(10H)-One
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.80 Å Release Date: 2014-05-28 Classification: TRANSFERASE Ligands: IV7 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-05-28
Ligands: IV7
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Structure Of The Human Anaplastic Lymphoma Kinase In Complex With The Inhibitor 3-((1R)-1-(5-Fluoro-2-Methoxyphenyl)Ethoxy)-5-(1-Methyl-1H- 1,2,3-Triazol-5-Yl)Pyridin-2-Amine
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.90 Å Release Date: 2014-05-28 Classification: TRANSFERASE Ligands: 3U9 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-05-28
Ligands: 3U9
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Structure Of The Human Anaplastic Lymphoma Kinase In Complex With The Inhibitor (5R)-8-Amino-3-Fluoro-5,19-Dimethyl-20-Oxo-5,18,19,20- Tetrahydro-7,11-(Azeno)Pyrido(2',1':2,3)Imidazo(4,5-H)(2,5,11) Benzoxadiazacyclotetradecine-14-Carbonitrile
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.79 Å Release Date: 2014-05-28 Classification: TRANSFERASE Ligands: KVC |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-05-28
Ligands: KVC
 |
Structure Of The Human Anaplastic Lymphoma Kinase In Complex With The Inhibitor 7-Amino-3-Cyclopropyl-12-Fluoro-1,10,16-Trimethyl-16,17- Dihydro-1H-8,4-(Metheno)Pyrazolo(4,3-H)(2,5,11) Benzoxadiazacyclotetradecin-15(10H)-One
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.03 Å Release Date: 2014-05-28 Classification: TRANSFERASE Ligands: J99 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-05-28
Ligands: J99
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Structure Of The Human Anaplastic Lymphoma Kinase In Complex With 3-((R)-1-(5-Fluoro-2-(2H-1,2,3-Triazol-2-Yl)Phenyl)Ethoxy)-5-(5-Methyl-1H- Pyrazol-4-Yl)Pyridin-2-Amine
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.03 Å Release Date: 2014-01-29 Classification: TRANSFERASE Ligands: OFG |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-01-29
Ligands: OFG