Search Count: 61
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Crystal Structure Of Kirsten Rat Sarcoma G12C Complexed With Gmppnp And Covalently Bound To 1-[(2R,3R)-3-{[(7P)-7-(8-Ethynyl-7-Fluoronaphthalen-1-Yl)-8-Fluoro-2-{ [(2R,4R,7As)-2-Fluorotetrahydro-1H-Pyrrolizin-7A(5H)-Yl]Methoxy}Pyrido[4,3-D] Pyrimidin-4-Yl](Methyl)Amino}-2-Methylpyrrolidin-1-Yl]-3-(Pyrazin-2-Yl)Propan-1-One
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.49 Å Release Date: 2026-03-04 Classification: HYDROLASE Ligands: GDP, A1C5K, CA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2026-03-04
Ligands: GDP, A1C5K, CA
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Crystal Structure Of Kirsten Rat Sarcoma G12C Complexed With Gmppnp And Covalently Bound To An Adduct Of {(2S)-4-[7-(8-Chloronaphthalen-1-Yl)-2-{[(2S)-1-Methylpyrrolidin-2-Yl]Methoxy}-5,6,7,8-Tetrahydropyrido[3,4-D]Pyrimidin-4-Yl]-1-[(2Z)-2-Fluoro-3-(Pyridin-2-Yl)Prop-2-Enoyl]Piperazin-2-Yl}Acetonitrile
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.59 Å Release Date: 2025-11-05 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: GNP, A1B7P, MG |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-11-05
Ligands: GNP, A1B7P, MG
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Crystal Structure Of Kirsten Rat Sarcoma G12C Complexed With Gdp And Covalently Bound To An Adduct Of (2S)-1-{4-[(7P)-7-(8-Ethynyl-7-Fluoro-3-Hydroxynaphthalen-1-Yl)-8-Fluoro-2-{[(2R,4R,7As)-2-Fluorotetrahydro-1H-Pyrrolizin-7A(5H)-Yl]Methoxy}Pyrido[4,3-D]Pyrimidin-4-Yl]Piperazin-1-Yl}-2-Fluoro-3-(1,3-Thiazol-2-Yl)Propan-1-One
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.50 Å Release Date: 2025-11-05 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: GDP, A1B7Q, MG |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-11-05
Ligands: GDP, A1B7Q, MG
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Human Sting G230A/R293Q Variant Bound To Cgamp
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.22 Å Release Date: 2025-06-18 Classification: MEMBRANE PROTEIN Ligands: 1SY |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-06-18
Ligands: 1SY
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Human Sting G230A/R293Q Variant Bound To Diabzi-A1
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.87 Å Release Date: 2025-06-18 Classification: MEMBRANE PROTEIN Ligands: A1A3A |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-06-18
Ligands: A1A3A
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Human Sting G230A/R293Q Variant Bound To Thiqi
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.10 Å Release Date: 2025-06-18 Classification: MEMBRANE PROTEIN Ligands: A1A4R |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-06-18
Ligands: A1A4R
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Human Sting G230A/R293Q Variant Bound To Diabzi-I
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.53 Å Release Date: 2025-06-18 Classification: MEMBRANE PROTEIN Ligands: A1A4W |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-06-18
Ligands: A1A4W
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Human Sting H232R Variant Bound To Abzi
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.95 Å Release Date: 2025-06-18 Classification: MEMBRANE PROTEIN Ligands: A1A4X |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-06-18
Ligands: A1A4X
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Crystal Structure Of Farnesoid X-Activated Receptor Complexed With Compound-32 Aka (1S,3S)-N-({4-[5-(2-Fluoropr Opan-2-Yl)-1,2,4-Oxadiazol-3-Yl]Bicyclo[2.2.2]Octan-1-Yl}M Ethyl)-3-Hydroxy-N-[4'-(2-Hydroxypropan-2-Yl)-[1,1'-Biphen Yl]-3-Yl]-3-(Trifluoromethyl)Cyclobutane-1-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.15 Å Release Date: 2022-06-29 Classification: NUCLEAR PROTEIN Ligands: IUS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-06-29
Ligands: IUS
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Crystal Structure Of Human Sting R232 In Complex With Compound 11
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.96 Å Release Date: 2022-02-09 Classification: IMMUNE SYSTEM Ligands: B7L |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-02-09
Ligands: B7L
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Protein Tyrosine Phosphatase 1B, Apo
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.77 Å Release Date: 2022-01-19 Classification: HYDROLASE Ligands: ACT, MG |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-01-19
Ligands: ACT, MG
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Protein Tyrosine Phosphatase 1B With Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.84 Å Release Date: 2022-01-19 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: WOV, MG |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-01-19
Ligands: WOV, MG
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Crystal Structure Of Tyrosine Kinase 2 Jh2 (Pseudo Kinase Domain) Complexed With Compound-12 Aka:6-[(Cyclopropanecarbonyl)Amino]-4-{[2-Methoxy-3-(Pyrimidin-2-Yl)Phenyl]Amino}-N-Methylpyridazine-3-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.82 Å Release Date: 2021-08-04 Classification: TRANSFERASE Ligands: VZJ |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-08-04
Ligands: VZJ
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Crystal Structure Of Tyrosine Kinase 2 Jh2 (Pseudo Kinase Domain) Complexed With Compound-12 Aka:6-[(Cyclopropanecarbonyl)Amino]-4-({3-[6-(Dimethylcarbamoyl)Pyridazin-3-Yl]-2-Methoxyphenyl}Amino)-N-Methylpyridazine-3-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.27 Å Release Date: 2021-08-04 Classification: TRANSFERASE Ligands: VZG |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-08-04
Ligands: VZG
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Crystal Structure Of Rar-Related Orphan Receptor C (Nhis-Rorgt(244-487)-L6-Src1(678-692) In Complex With An Azatricyclic Rorgt Inverse Agonist
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.09 Å Release Date: 2021-05-12 Classification: TRANSFERASE Ligands: YDY |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-05-12
Ligands: YDY
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Crystal Structure Of Rar-Related Orphan Receptor C (Nhis-Rorgt(244-487)-L6-Src1(678-692) In Complex With A Novel Tricyclic-Carbocylic Rorgt Inverse Agonist
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.65 Å Release Date: 2021-02-24 Classification: TRANSCRIPTION/Agonist Ligands: Z8G |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-02-24
Ligands: Z8G
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Crystal Structure Of Rar-Related Orphan Receptor C (Nhis-Rorgt(244-487)-L6-Src1(678-692)) In Complex With {3,5-Dichloro-4-[4-Methoxy-3-(Propan-2-Yl)Phenoxy]Phenyl}Methanol
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.62 Å Release Date: 2021-01-20 Classification: TRANSFERASE/Agonist Ligands: Z7G |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-01-20
Ligands: Z7G
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Crystal Structure Of Rar-Related Orphan Receptor C (Nhis-Rorgt(244-487)-L6-Src1(678-692)) In Complex With {3,5-Dichloro-4-[4-Methoxy-3-(Propan-2-Yl)Phenoxy]Phenyl}Methanol
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.42 Å Release Date: 2021-01-20 Classification: TRANSFERASE/Agonist Ligands: Z7H |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-01-20
Ligands: Z7H
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Crystal Structure Of Rar-Related Orphan Receptor C (Nhis-Rorgt(244-487)-L6-Src1(678-692)) In Complex With {3,5-Dichloro-4-[4-Methoxy-3-(Propan-2-Yl)Phenoxy]Phenyl}Methanol
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.14 Å Release Date: 2021-01-20 Classification: TRANSFERASE/Agonist Ligands: Z7I |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-01-20
Ligands: Z7I
 |
Crystal Structure Of Hpk1 (Map4K1) Kinase In Complex With 5-{[4-{[(1S)-2-Hydroxy-1-Phenylethyl]Amino}-5-(1,3,4-Oxadiazol-2-Yl)Pyrimidin-2-Yl]Amino}-3,3-Dimethyl-2-Benzofuran-1(3H)-One
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.85 Å Release Date: 2021-01-13 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: W9D |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-01-13
Ligands: W9D