Search Count: 20
 |
Estrogen Receptor Alpha Y537S Covalently Bound To Antagonist H3B-5942.
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.89 Å Release Date: 2018-03-21 Classification: nuclear protein/antagonist Ligands: F3D, EDO, DMS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-03-21
Ligands: F3D, EDO, DMS
 |
Estrogen Receptor Alpha Y537S Bound To Antagonist H3B-9224.
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.68 Å Release Date: 2018-03-21 Classification: nuclear protein/antagonist Ligands: F3D, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-03-21
Ligands: F3D, EDO
 |
Crystal Structure Of Fgfr1-Y563C (Fgfr4 Surrogate) Covalently Bound To H3B-6527
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.20 Å Release Date: 2017-05-24 Classification: transferase/transferase inhibitor Ligands: 9ES, SO4, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-05-24
Ligands: 9ES, SO4, EDO
 |
The Crystal Structure Of Human Nicotinamide Phosphoribosyltransferase (Nampt) In Complex With N-(4-{(S)-[1-(2-Methylpropyl)Piperidin-4-Yl]Sulfinyl}Benzyl)Furo[2,3-C]Pyridine-2-Carboxamide Inhibitor (Compound 21)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.72 Å Release Date: 2015-02-11 Classification: Transferase/Transferase inhibitor Ligands: 3TQ, PO4, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-02-11
Ligands: 3TQ, PO4, EDO
 |
Discovery Of Potent And Efficacious Cyanoguanidine-Containing Nicotinamide Phosphoribosyltransferase (Nampt) Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.69 Å Release Date: 2013-12-25 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: LTS, PO4, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-12-25
Ligands: LTS, PO4, EDO
 |
Discovery Of Potent And Efficacious Cyanoguanidine-Containing Nicotinamide Phosphoribosyltransferase (Nampt) Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.64 Å Release Date: 2013-12-25 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: LWW, PO4, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-12-25
Ligands: LWW, PO4, EDO
 |
Fragment-Based Identification Of Amides Derived From Trans-2-(Pyridin-3-Yl)Cyclopropanecarboxylic Acid As Potent Inhibitors Of Human Nicotinamide Phosphoribosyltransferase (Nampt)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.81 Å Release Date: 2013-09-25 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 20J, PO4, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-09-25
Ligands: 20J, PO4, EDO
 |
Fragment-Based Identification Of Amides Derived From Trans-2-(Pyridin-3-Yl)Cyclopropanecarboxylic Acid As Potent Inhibitors Of Human Nicotinamide Phosphoribosyltransferase (Nampt)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.55 Å Release Date: 2013-09-25 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 20M, PO4, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-09-25
Ligands: 20M, PO4, EDO
 |
Fragment-Based Identification Of Amides Derived From Trans-2-(Pyridin-3-Yl)Cyclopropanecarboxylic Acid As Potent Inhibitors Of Human Nicotinamide Phosphoribosyltransferase (Nampt)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.84 Å Release Date: 2013-09-25 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 20N, PO4, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-09-25
Ligands: 20N, PO4, EDO
 |
Fragment-Based Identification Of Amides Derived From Trans-2-(Pyridin-3-Yl)Cyclopropanecarboxylic Acid As Potent Inhibitors Of Human Nicotinamide Phosphoribosyltransferase (Nampt)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.75 Å Release Date: 2013-09-25 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: PO4, 1EB, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-09-25
Ligands: PO4, 1EB, EDO
 |
Fragment-Based Identification Of Amides Derived From Trans-2-(Pyridin-3-Yl)Cyclopropanecarboxylic Acid As Potent Inhibitors Of Human Nicotinamide Phosphoribosyltransferase (Nampt)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.50 Å Release Date: 2013-09-25 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 20P, PO4, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-09-25
Ligands: 20P, PO4, EDO
 |
Fragment-Based Identification Of Amides Derived From Trans-2-(Pyridin-3-Yl)Cyclopropanecarboxylic Acid As Potent Inhibitors Of Human Nicotinamide Phosphoribosyltransferase (Nampt)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.70 Å Release Date: 2013-09-25 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 20O, PO4, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-09-25
Ligands: 20O, PO4, EDO
 |
Identification Of Amides Derived From 1H-Pyrazolo[3,4-B]Pyridine-5-Carboxylic Acid As Potent Inhibitors Of Human Nicotinamide Phosphoribosyltransferase (Nampt)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.75 Å Release Date: 2013-09-25 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 20R, PO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-09-25
Ligands: 20R, PO4
 |
Identification Of Amides Derived From 1H-Pyrazolo[3,4-B]Pyridine-5-Carboxylic Acid As Potent Inhibitors Of Human Nicotinamide Phosphoribosyltransferase (Nampt)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.41 Å Release Date: 2013-09-25 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 20T, POP, PO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-09-25
Ligands: 20T, POP, PO4
 |
Discovery Of Potent And Efficacious Urea-Containing Nicotinamide Phosphoribosyltransferase (Nampt) Inhibitors With Reduced Cyp2C9 Inhibition Properties
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.20 Å Release Date: 2013-05-29 Classification: Transferase/Transferase inhibitor Ligands: 1LJ, PO4, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-05-29
Ligands: 1LJ, PO4, EDO
 |
Structure-Based Identification Of Ureas As Novel Nicotinamide Phosphoribosyltransferase (Nampt) Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.91 Å Release Date: 2013-05-08 Classification: Transferase/Transferase inhibitor Ligands: 1LS, PO4, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-05-08
Ligands: 1LS, PO4, EDO
 |
Structure-Based Discovery Of Novel Amide-Containing Nicotinamide Phosphoribosyltransferase (Nampt) Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.60 Å Release Date: 2013-05-08 Classification: Transferase/Transferase Inhibitor Ligands: 1QR, PO4, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-05-08
Ligands: 1QR, PO4, EDO
 |
Structure-Based Discovery Of Novel Amide-Containing Nicotinamide Phosphoribosyltransferase (Nampt) Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.60 Å Release Date: 2013-05-08 Classification: Transferase/transferase Inhibitor Ligands: 1QS, PO4, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-05-08
Ligands: 1QS, PO4, EDO
 |
Structure Of Plk1 Kinase Domain In Complex With A Benzolactam-Derived Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.50 Å Release Date: 2011-11-23 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: ZN, 3TA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-11-23
Ligands: ZN, 3TA
 |
Crystal Structure Of Hiv-1 Reverse Transcriptase In Complex With Gw490745
Organism: Human immunodeficiency virus 1
Method: X-RAY DIFFRACTION Resolution:2.85 Å Release Date: 2004-12-07 Classification: TRANSFERASE Ligands: GWB |
Organism: Human immunodeficiency virus 1
Method: X-RAY DIFFRACTION
Release Date: 2004-12-07
Ligands: GWB