Search Count: 13
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Trka With (6~{R})-3-Methylsulfanyl-6-Phenyl-1-(1~{H}-Pyrazol-3-Yl)-6,7-Dihydro-5~{H}-Thieno[3,4-C]Pyridin-4-One
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.33 Å Release Date: 2017-08-09 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 69C, CL, ACT |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-08-09
Ligands: 69C, CL, ACT
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Discovery Of Mli-2, An Orally Available And Selective Lrrk2 Inhibitor That Reduces Brain Kinase Activity
Organism: Rattus norvegicus
Method: X-RAY DIFFRACTION Resolution:1.69 Å Release Date: 2017-03-15 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 81Y, SO4 |
Organism: Rattus norvegicus
Method: X-RAY DIFFRACTION
Release Date: 2017-03-15
Ligands: 81Y, SO4
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Structures Of The Human Ox1 Orexin Receptor Bound To Selective And Dual Antagonists
Organism: Homo sapiens, Pyrococcus abyssi (strain ge5 / orsay)
Method: X-RAY DIFFRACTION Resolution:2.75 Å Release Date: 2016-03-09 Classification: SIGNALING PROTEIN Ligands: SUV, OLA |
Organism: Homo sapiens, Pyrococcus abyssi (strain ge5 / orsay)
Method: X-RAY DIFFRACTION
Release Date: 2016-03-09
Ligands: SUV, OLA
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Structures Of The Human Ox1 Orexin Receptor Bound To Selective And Dual Antagonists
Organism: Homo sapiens, Pyrococcus abyssi (strain ge5 / orsay)
Method: X-RAY DIFFRACTION Resolution:2.83 Å Release Date: 2016-03-09 Classification: SIGNALING PROTEIN Ligands: 4OT, OLA |
Organism: Homo sapiens, Pyrococcus abyssi (strain ge5 / orsay)
Method: X-RAY DIFFRACTION
Release Date: 2016-03-09
Ligands: 4OT, OLA
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Pde10 Complexed With 5-Chloro-N-[(2,4-Dimethylthiazol-5-Yl)Methyl]Pyrazolo[1,5-A]Pyrimidin-7-Amine
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.20 Å Release Date: 2016-01-27 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: ZN, MG, 5AV, 4PX |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-01-27
Ligands: ZN, MG, 5AV, 4PX
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Pde10 Complexed With N-[(1-Methylpyrazol-4-Yl)Methyl]-5-[[(1S,2S)-2-(2-Pyridyl)Cyclopropyl]Methoxy]Pyrazolo[1,5-A]Pyrimidin-7-Amine
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.00 Å Release Date: 2016-01-27 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: ZN, MG, 5AY |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-01-27
Ligands: ZN, MG, 5AY
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Pde10 Complexed With6-Chloro-N-[(2,4-Dimethylthiazol-5-Yl)Methyl]-5-Methyl-2-[2-(2-Pyridyl)Ethoxy]Pyrimidin-4-Amine
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.10 Å Release Date: 2015-12-02 Classification: hydrolase/hydrolase inhibitor Ligands: ZN, MG, 4PX, 4Y1 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-12-02
Ligands: ZN, MG, 4PX, 4Y1
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Pde10 Complexed With 6-Chloro-N-[(2,4-Dimethylthiazol-5-Yl)Methyl]-5-Methyl-2-[3-(2-Quinolyl)Propoxy]Pyrimidin-4-Amine
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.09 Å Release Date: 2015-10-07 Classification: hydrolase/hydrolase inhibitor Ligands: ZN, MG, 4PX, 4XU |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-10-07
Ligands: ZN, MG, 4PX, 4XU
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Pde10 Complexed With 4,6-Dichloro-2-Cyclopropyl-5-Methyl-Pyrimidine
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.70 Å Release Date: 2015-09-30 Classification: hydrolase/hydrolase inhibitor Ligands: ZN, MG, 4XS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-09-30
Ligands: ZN, MG, 4XS
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Pde10 Complexed With 6-Chloro-2-Cyclopropyl-5-Methyl-Pyrimidin-4-Amine
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.56 Å Release Date: 2015-09-30 Classification: hydrolase/hydrolase inhibitor Ligands: ZN, MG, 4XV |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-09-30
Ligands: ZN, MG, 4XV
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Pde10 Complexed With 6-Chloro-2-Cyclopropyl-5-Methyl-N-Propyl-Pyrimidin-4-Amine
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.05 Å Release Date: 2015-09-30 Classification: hydrolase/hydrolase inhibitor Ligands: ZN, MG, 4XY |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-09-30
Ligands: ZN, MG, 4XY
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Pde10 Complexed With 6-Chloro-2-Cyclopropyl-N-[(2,4-Dimethylthiazol-5-Yl)Methyl]-5-Methyl-Pyrimidin-4-Amine
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.00 Å Release Date: 2015-09-30 Classification: hydrolase/hydrolase inhibitor Ligands: ZN, MG, 4Y2 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-09-30
Ligands: ZN, MG, 4Y2
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Pde10 Complexed With 4-Isopropoxy-2-(2-(3-(4-Methoxyphenyl)-4-Oxo-3,4-Dihydroquinazolin-2-Yl)Ethyl)Isoindoline-1,3-Dione
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.50 Å Release Date: 2015-08-12 Classification: hydrolase/hydrolase inhibitor Ligands: ZN, MG, 4PX, 4Q0 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-08-12
Ligands: ZN, MG, 4PX, 4Q0