Search Count: 10
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Multi-Parameter Lead Optimization To Give An Oral Chk1 Inhibitor Clinical Candidate: (R)-5-((4-((Morpholin-2-Ylmethyl)Amino)-5-(Trifluoromethyl)Pyridin-2-Yl)Amino)Pyrazine-2-Carbonitrile (Cct245737)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.91 Å Release Date: 2016-05-25 Classification: TRANSFERASE Ligands: 5UY, EDO, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-05-25
Ligands: 5UY, EDO, GOL
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Crystal Structure Of Checkpoint Kinase 1 (Chk1) In Complex With Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.01 Å Release Date: 2012-01-11 Classification: TRANSFERASE Ligands: YM3, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2012-01-11
Ligands: YM3, EDO
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Crystal Structure Of Checkpoint Kinase 1 (Chk1) In Complex With Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.35 Å Release Date: 2012-01-11 Classification: TRANSFERASE Ligands: 4YM, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2012-01-11
Ligands: 4YM, EDO
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Crystal Structure Of Checkpoint Kinase 1 (Chk1) In Complex With Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.03 Å Release Date: 2012-01-11 Classification: TRANSFERASE Ligands: YM5, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2012-01-11
Ligands: YM5, EDO
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Crystal Structure Of Checkpoint Kinase 1 (Chk1) In Complex With Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.01 Å Release Date: 2012-01-11 Classification: TRANSFERASE Ligands: YM6, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2012-01-11
Ligands: YM6, EDO
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Crystal Structure Of Checkpoint Kinase 1 (Chk1) In Complex With Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.81 Å Release Date: 2012-01-11 Classification: TRANSFERASE Ligands: YM7, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2012-01-11
Ligands: YM7, EDO
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Crystal Structure Of Checkpoint Kinase 1 (Chk1) In Complex With Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.07 Å Release Date: 2012-01-11 Classification: TRANSFERASE Ligands: YM8, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2012-01-11
Ligands: YM8, EDO
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Crystal Structure Of Checkpoint Kinase 1 (Chk1) In Complex With Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.25 Å Release Date: 2010-07-07 Classification: TRANSFERASE Ligands: XEZ, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2010-07-07
Ligands: XEZ, EDO
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Crystal Structure Of Checkpoint Kinase 1 (Chk1) In Complex With Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.70 Å Release Date: 2010-06-30 Classification: TRANSFERASE Ligands: YVQ |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2010-06-30
Ligands: YVQ
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Crystal Structure Of Checkpoint Kinase 1 (Chk1) In Complex With Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.40 Å Release Date: 2010-06-30 Classification: TRANSFERASE Ligands: 4UB, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2010-06-30
Ligands: 4UB, EDO