Search Count: 36
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Crystal Structure Of Plasmodium Falciparum Dihydroorotate Dehydrogenase Bound With Inhibitor Dsm1010 (6-Cyclopropyl-2,4-Dimethyl-3-(4-(Trifluoromethyl)Benzyl)-2,6-Dihydro-7H-Pyrazolo[3,4-C]Pyridin-7-One)
Organism: Plasmodium falciparum 3d7
Method: X-RAY DIFFRACTION Resolution:3.00 Å Release Date: 2025-01-29 Classification: OXIDOREDUCTASE Ligands: A1A5P, FMN, OG6 |
Organism: Plasmodium falciparum 3d7
Method: X-RAY DIFFRACTION
Release Date: 2025-01-29
Ligands: A1A5P, FMN, OG6
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Crystal Structure Of Plasmodium Falciparum Dihydroorotate Dehydrogenase Bound With Inhibitor Dsm679 (Ethyl 1,4-Dimethyl-5-((6-(Trifluoromethyl)Pyridin-3-Yl)Methyl)-1H-Pyrazole-3-Carboxylate)
Organism: Plasmodium falciparum 3d7
Method: X-RAY DIFFRACTION Resolution:2.41 Å Release Date: 2025-01-01 Classification: OXIDOREDUCTASE/INHIBITOR Ligands: A1A51, FMN, OG6, CIT, LDA |
Organism: Plasmodium falciparum 3d7
Method: X-RAY DIFFRACTION
Release Date: 2025-01-01
Ligands: A1A51, FMN, OG6, CIT, LDA
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Crystal Structure Of Plasmodium Falciparum Dihydroorotate Dehydrogenase Bound With Inhibitor Dsm681 (N-Cyclopropyl-1,4-Dimethyl-5-((6-(Trifluoromethyl)Pyridin-3-Yl)Methyl)-1H-Pyrazole-3-Carboxamide)
Organism: Plasmodium falciparum 3d7
Method: X-RAY DIFFRACTION Resolution:2.10 Å Release Date: 2025-01-01 Classification: OXIDOREDUCTASE/INHIBITOR Ligands: A1A52, FMN, OG6, NA |
Organism: Plasmodium falciparum 3d7
Method: X-RAY DIFFRACTION
Release Date: 2025-01-01
Ligands: A1A52, FMN, OG6, NA
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Crystal Structure Of Plasmodium Falciparum Dihydroorotate Dehydrogenase Bound With Inhibitor Dsm959 (6-Cyclopropyl-2,4-Dimethyl-3-((6-(Trifluoromethyl)Pyridin-3-Yl)Methyl)-2,6-Dihydro-7H-Pyrazolo[3,4-C]Pyridin-7-One)
Organism: Plasmodium falciparum 3d7
Method: X-RAY DIFFRACTION Resolution:3.10 Å Release Date: 2025-01-01 Classification: OXIDOREDUCTASE/INHIBITOR Ligands: A1A53, FMN, OG6 |
Organism: Plasmodium falciparum 3d7
Method: X-RAY DIFFRACTION
Release Date: 2025-01-01
Ligands: A1A53, FMN, OG6
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Crystal Structure Of Plasmodium Falciparum Dihydroorotate Dehydrogenase Bound With Inhibitor Dsm1153 (4,6-Dicyclopropyl-3-(3-Fluoro-4-(Trifluoromethyl)Benzyl)-2-Methyl-2,6-Dihydro-7H-Pyrazolo[3,4-D]Pyridazin-7-One)
Organism: Plasmodium falciparum 3d7
Method: X-RAY DIFFRACTION Resolution:3.15 Å Release Date: 2025-01-01 Classification: OXIDOREDUCTASE Ligands: A1A5Q, FMN, OG6 |
Organism: Plasmodium falciparum 3d7
Method: X-RAY DIFFRACTION
Release Date: 2025-01-01
Ligands: A1A5Q, FMN, OG6
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Crystal Structure Of Plasmodium Falciparum Dihydroorotate Dehydrogenase Bound With Inhibitor Dsm1174 (3-((7-Azaspiro[3.5]Nonan-7-Yl)Methyl)-4-Cyclopropyl-6-Ethyl-2-Methyl-2,6-Dihydro-7H-Pyrazolo[3,4-C]Pyridin-7-One)
Organism: Plasmodium falciparum 3d7
Method: X-RAY DIFFRACTION Resolution:3.30 Å Release Date: 2025-01-01 Classification: OXIDOREDUCTASE Ligands: A1A59, FMN, OG6 |
Organism: Plasmodium falciparum 3d7
Method: X-RAY DIFFRACTION
Release Date: 2025-01-01
Ligands: A1A59, FMN, OG6
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Crystal Structure Of Plasmodium Falciparum Dihydroorotate Dehydrogenase Bound With Inhibitor Dsm1398 ((S)-3-(Amino(3-Chloro-4-(Trifluoromethyl)Phenyl)(Cyclopropyl)Methyl)-6-Cyclopropyl-2-Methyl-2,6-Dihydro-7H-Pyrazolo[3,4-D]Pyridazin-7-One)
Organism: Plasmodium falciparum 3d7
Method: X-RAY DIFFRACTION Resolution:2.90 Å Release Date: 2025-01-01 Classification: OXIDOREDUCTASE Ligands: A1A6D, FMN, OG6, ACY |
Organism: Plasmodium falciparum 3d7
Method: X-RAY DIFFRACTION
Release Date: 2025-01-01
Ligands: A1A6D, FMN, OG6, ACY
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Crystal Structure Of Plasmodium Falciparum Dihydroorotate Dehydrogenase Bound With Inhibitor Dsm1211 ((R)-3-(Amino(6-(Trifluoromethyl)Pyridin-3-Yl)Methyl)-4-Cyclopropyl-6-Ethyl-2-Methyl-2,6-Dihydro-7H-Pyrazolo[3,4-C]Pyridin-7-One)
Organism: Plasmodium falciparum 3d7
Method: X-RAY DIFFRACTION Resolution:3.10 Å Release Date: 2025-01-01 Classification: OXIDOREDUCTASE Ligands: A1A6E, FMN, OG6 |
Organism: Plasmodium falciparum 3d7
Method: X-RAY DIFFRACTION
Release Date: 2025-01-01
Ligands: A1A6E, FMN, OG6
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Acinetobacter Baumannii Dihydroorotate Dehydrogenase Bound With Inhibitor Dsm186
Organism: Acinetobacter baumannii
Method: X-RAY DIFFRACTION Resolution:1.40 Å Release Date: 2022-12-28 Classification: OXIDOREDUCTASE/INHIBITOR Ligands: OBR, FMN, ORO, GOL |
Organism: Acinetobacter baumannii
Method: X-RAY DIFFRACTION
Release Date: 2022-12-28
Ligands: OBR, FMN, ORO, GOL
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Crystal Structure Of Plasmodium Falciparum Dihydroorotate Dehydrogenase Bound With Inhibitor Dsm589 (Ethyl 3-Methyl-4-((4-(Trifluoromethyl)Benzo[D]Oxazol-7-Yl)Methyl)-1H-Pyrrole-2-Carboxylate)
Organism: Plasmodium falciparum (isolate 3d7)
Method: X-RAY DIFFRACTION Resolution:2.15 Å Release Date: 2021-05-19 Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR Ligands: XAJ, FMN, ORO |
Organism: Plasmodium falciparum (isolate 3d7)
Method: X-RAY DIFFRACTION
Release Date: 2021-05-19
Ligands: XAJ, FMN, ORO
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Crystal Structure Of Plasmodium Falciparum Dihydroorotate Dehydrogenase Bound With Inhibitor Dsm634 (3-Methyl-N-(1-(5-Methylisoxazol-3-Yl)Ethyl)-4-(4-(Trifluoromethyl)Benzyl)-1H-Pyrrole-2-Carboxamide)
Organism: Plasmodium falciparum (isolate 3d7)
Method: X-RAY DIFFRACTION Resolution:2.40 Å Release Date: 2021-05-19 Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR Ligands: XBY, FMN, ORO, GOL |
Organism: Plasmodium falciparum (isolate 3d7)
Method: X-RAY DIFFRACTION
Release Date: 2021-05-19
Ligands: XBY, FMN, ORO, GOL
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Crystal Structure Of Plasmodium Falciparum Dihydroorotate Dehydrogenase Bound With Inhibitor Dsm697 (3-Methyl-N-(1-(5-Methylisoxazol-3-Yl)Ethyl)-4-(6-(Trifluoromethyl)-1H-Indol-3-Yl)-1H-Pyrrole-2-Carboxamide)
Organism: Plasmodium falciparum (isolate 3d7)
Method: X-RAY DIFFRACTION Resolution:2.00 Å Release Date: 2021-05-19 Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR Ligands: XCD, FMN, ORO |
Organism: Plasmodium falciparum (isolate 3d7)
Method: X-RAY DIFFRACTION
Release Date: 2021-05-19
Ligands: XCD, FMN, ORO
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Crystal Structure Of Plasmodium Falciparum Dihydroorotate Dehydrogenase Bound With Inhibitor Dsm705 (N-(1-(1H-1,2,4-Triazol-3-Yl)Ethyl)-3-Methyl-4-(1-(6-(Trifluoromethyl)Pyridin-3-Yl)Cyclopropyl)-1H-Pyrrole-2-Carboxamide)
Organism: Plasmodium falciparum (isolate 3d7)
Method: X-RAY DIFFRACTION Resolution:1.75 Å Release Date: 2021-05-19 Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR Ligands: XC7, FMN, ORO, MG |
Organism: Plasmodium falciparum (isolate 3d7)
Method: X-RAY DIFFRACTION
Release Date: 2021-05-19
Ligands: XC7, FMN, ORO, MG
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Crystal Structure Of Plasmodium Falciparum Dihydroorotate Dehydrogenase Bound With Inhibitor Dsm778 (3-Methyl-N-(1-(5-Methyl-1H-Pyrazol-3-Yl)Ethyl)-4-(1-(6-(Trifluoromethyl)Pyridin-3-Yl)Cyclopropyl)-1H-Pyrrole-2-Carboxamide)
Organism: Plasmodium falciparum (isolate 3d7)
Method: X-RAY DIFFRACTION Resolution:1.75 Å Release Date: 2021-05-19 Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR Ligands: XCM, FMN, ORO |
Organism: Plasmodium falciparum (isolate 3d7)
Method: X-RAY DIFFRACTION
Release Date: 2021-05-19
Ligands: XCM, FMN, ORO
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Crystal Structure Of Plasmodium Falciparum Dihydroorotate Dehydrogenase Bound With Inhibitor Dsm782 (N-(1-(5-Cyano-1H-Pyrazol-3-Yl)Ethyl)-3-Methyl-4-(1-(6-(Trifluoromethyl)Pyridin-3-Yl)Cyclopropyl)-1H-Pyrrole-2-Carboxamide)
Organism: Plasmodium falciparum (isolate 3d7)
Method: X-RAY DIFFRACTION Resolution:1.60 Å Release Date: 2021-05-19 Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR Ligands: XCV, FMN, ORO |
Organism: Plasmodium falciparum (isolate 3d7)
Method: X-RAY DIFFRACTION
Release Date: 2021-05-19
Ligands: XCV, FMN, ORO
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Crystal Structure Of Plasmodium Falciparum Dihydroorotate Dehydrogenase Bound With Inhibitor Dsm784 (3-(1-(3-Methyl-4-((6-(Trifluoromethyl)Pyridin-3-Yl)Methyl)-1H-Pyrrole-2-Carboxamido)Ethyl)-1H-Pyrazole-5-Carboxamide)
Organism: Plasmodium falciparum (isolate 3d7)
Method: X-RAY DIFFRACTION Resolution:1.96 Å Release Date: 2021-05-19 Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR Ligands: XE7, FMN, ORO |
Organism: Plasmodium falciparum (isolate 3d7)
Method: X-RAY DIFFRACTION
Release Date: 2021-05-19
Ligands: XE7, FMN, ORO
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Crystal Structure Of Plasmodium Falciparum Dihydroorotate Dehydrogenase Bound With Inhibitor Dsm557
Organism: Plasmodium falciparum (isolate 3d7)
Method: X-RAY DIFFRACTION Resolution:2.25 Å Release Date: 2020-04-22 Classification: OXIDOREDUCTASE Ligands: RL7, FMN, ORO |
Organism: Plasmodium falciparum (isolate 3d7)
Method: X-RAY DIFFRACTION
Release Date: 2020-04-22
Ligands: RL7, FMN, ORO
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Crystal Structure Of Plasmodium Falciparum Dihydroorotate Dehydrogenase Bound With Inhibitor Dsm483
Organism: Plasmodium falciparum (isolate 3d7)
Method: X-RAY DIFFRACTION Resolution:1.78 Å Release Date: 2020-04-22 Classification: OXIDOREDUCTASE Ligands: RLA, FMN, ORO |
Organism: Plasmodium falciparum (isolate 3d7)
Method: X-RAY DIFFRACTION
Release Date: 2020-04-22
Ligands: RLA, FMN, ORO
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Crystal Structure Of Plasmodium Falciparum Topoisomerase Ii Dna-Binding, Cleavage And Re-Ligation Domain
Organism: Plasmodium falciparum
Method: X-RAY DIFFRACTION Resolution:2.33 Å Release Date: 2019-02-06 Classification: ISOMERASE |
Organism: Plasmodium falciparum
Method: X-RAY DIFFRACTION
Release Date: 2019-02-06
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Plasmodium Falciparum Dihydroorotate Dehydrogenase C276F Mutant Bound With Triazolopyrimidine-Based Inhibitor Dsm1
Organism: Plasmodium falciparum
Method: X-RAY DIFFRACTION Resolution:2.10 Å Release Date: 2018-11-14 Classification: OXIDOREDUCTASE Ligands: JZ8, FMN, ORO, GOL, LDA |
Organism: Plasmodium falciparum
Method: X-RAY DIFFRACTION
Release Date: 2018-11-14
Ligands: JZ8, FMN, ORO, GOL, LDA