Search Count: 19
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Crystal Structure Of Glucokinase (Hexokinase 4) Complexed With Ligand Diethyl ({2-[3-(4-Methanesulfonylpheno Xy)-5-{[(2S)-1-Methoxypropan-2-Yl]Oxy}Benzamido]-1,3-Thiaz Ol-4-Yl}Methyl)Phosphonate
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.40 Å Release Date: 2022-03-02 Classification: TRANSFERASE Ligands: GLC, NA, G2T, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-03-02
Ligands: GLC, NA, G2T, EDO
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Crystal Structure Of Glucokinase (Hexokinase 4) Complexed With Ligand Aka Diethyl {[3-(3-{[5-(Azetidine-1-Carbon Yl)Pyrazin-2-Yl]Oxy}-5-(Propan-2-Yloxy)Benzamido)-1H- Pyrazol-1-Yl]Methyl}Phosphonate
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.40 Å Release Date: 2022-03-02 Classification: TRANSFERASE Ligands: G1S, GLC |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-03-02
Ligands: G1S, GLC
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Crystal Structure Of The Human Brd2 Bd1 Bromodomain In Complex With 9-(Cyclopropylmethyl)-7-[(2R,6S)-2,6-Dimethylmorpholine-4-Carbonyl]-3-(3,5-Dimethyl-1,2-Oxazol-4-Yl)-9H-Carbazole-1-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.49 Å Release Date: 2021-09-29 Classification: CELL CYCLE Ligands: YW1, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-09-29
Ligands: YW1, EDO
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Crystal Structure Of The First Bromodomain Of Human Brd4 In Complex With 9-Benzyl-2-(3,5-Dimethyl-1,2-Oxazol-4-Yl)-7-(2-Hydroxypropan-2-Yl)-9H-Carbazole-4-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.10 Å Release Date: 2021-09-29 Classification: CELL CYCLE Ligands: YW4, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-09-29
Ligands: YW4, EDO
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Crystal Structure Of The First Bromodomain Of Human Brd4 In Complex With 2-(3,5-Dimethyl-1,2-Oxazol-4-Yl)-7-(2-Hydroxypropan-2-Yl)-9-[(S)-(Oxan-4-Yl)(Phenyl)Methyl]-9H-Carbazole-4-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.85 Å Release Date: 2021-09-29 Classification: CELL CYCLE Ligands: YW7, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-09-29
Ligands: YW7, EDO
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Crystal Structure Of The First Bromodomain Of Human Brd4 In Complex With Bms-986158, 2-{3-(1,4-Dimethyl-1H-1,2,3-Triazol-5-Yl)-5-[(S)-(Oxan-4-Yl)(Phenyl)Methyl]-5H-Pyrido[3,2-B]Indol-7-Yl}Propan-2-Ol
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.85 Å Release Date: 2021-09-29 Classification: CELL CYCLE Ligands: YWA, IOD, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-09-29
Ligands: YWA, IOD, EDO
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Discovery Of Bms-986144, A Third Generation, Pan Genotype Ns3/4A Protease Inhibitor For The Treatment Of Hepatitis C Virus Infection
Organism: Hepacivirus c
Method: X-RAY DIFFRACTION Resolution:2.15 Å Release Date: 2020-12-16 Classification: VIRAL PROTEIN Ligands: ZN, GXO |
Organism: Hepacivirus c
Method: X-RAY DIFFRACTION
Release Date: 2020-12-16
Ligands: ZN, GXO
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Irak4 In Complex With Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.19 Å Release Date: 2020-11-25 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: EXF, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-11-25
Ligands: EXF, SO4
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Crystal Structure Of Interleukin-1 Receptor-Associated Kinase 4 (Irak4-Wt) Complex With A Nicotinamide Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.07 Å Release Date: 2020-06-24 Classification: TRANSFERASE/TRANSFERASE Inhibitor Ligands: R7S, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-06-24
Ligands: R7S, SO4
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Factor Xia In Complex With The Inhibitor Methyl ((10R,14S)- 14-(4-(3-Chloro-2,6-Difluorophenyl)-6-Oxo-3,6-Dihydro- 1(2H)-Pyridinyl)-10-Methyl-9-Oxo-8,16- Diazatricyclo[13.3.1.0~2,7~]Nonadeca-1(19),2,4,6,15,17- Hexaen-5-Yl)Carbamate
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.95 Å Release Date: 2020-06-10 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: SWP, SO4, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-06-10
Ligands: SWP, SO4, EDO
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Factor Xia In Complex With The Inhibitor Methyl [(3R,7S)-7-{[5-Amino-1-(3-Chloro-2-Fluorophenyl)-1H-Pyrazole-4-Carbonyl]Amino}-3-Methyl-2-Oxo-2,3,4,5,6,7-Hexahydro-1H-12,8-(Metheno)-1,9-Benzodiazacyclotetradecin-15-Yl]Carbamate
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.23 Å Release Date: 2019-12-25 Classification: HYDROLASE/HYDROLASE inhibitor Ligands: QEY, SO4, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-12-25
Ligands: QEY, SO4, EDO
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Factor Xia In Complex With The Inhibitor Methyl [(3R,7S)-7-{[1-(3-Chloro-2-Fluorophenyl)-5-Methyl-1H-Imidazole-4-Carbonyl]Amino}-3-Methyl-2-Oxo-2,3,4,5,6,7-Hexahydro-1H-12,8-(Metheno)-1,9-Benzodiazacyclotetradecin-15-Yl]Carbamate
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.53 Å Release Date: 2019-12-25 Classification: HYDROLASE/HYDROLASE inhibitor Ligands: QEV, SO4, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-12-25
Ligands: QEV, SO4, EDO
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Crystal Structure Of Rar-Related Orphan Receptor C (Nhis- Rorgt(244-487)-L6-Src1(678-692)) In Complex With A Tricyclic Inverse Agonist
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.61 Å Release Date: 2019-11-06 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: O5B, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-11-06
Ligands: O5B, GOL
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Btk In Complex With Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.42 Å Release Date: 2019-04-03 Classification: TRANSFERASE/INHIBITOR Ligands: LTJ |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-04-03
Ligands: LTJ
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Crystal Structure Of Hepatis C Virus Protease (Ns3) Complexed With Tripeptidic Acyl Sulfonamide Inhibitor (Compound 16)
Organism: Hepatitis c virus
Method: X-RAY DIFFRACTION Resolution:1.69 Å Release Date: 2018-03-21 Classification: HYDROLASE Ligands: Z1B, ZN, CL, ACT |
Organism: Hepatitis c virus
Method: X-RAY DIFFRACTION
Release Date: 2018-03-21
Ligands: Z1B, ZN, CL, ACT
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Crystal Structure Of Hepatis C Virus Protease (Ns3) Complexed With Tripeptidic Acyl Sulfonamide Inhibitor (Compound 18)
Organism: Hepatitis c virus
Method: X-RAY DIFFRACTION Resolution:1.97 Å Release Date: 2018-03-21 Classification: HYDROLASE Ligands: Z1E, ZN |
Organism: Hepatitis c virus
Method: X-RAY DIFFRACTION
Release Date: 2018-03-21
Ligands: Z1E, ZN
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Crystal Structure Of Pi3K Delta In Complex With A Trifluoro-Ethyl-Pyrazol-Pyrolotriazine Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.80 Å Release Date: 2017-06-07 Classification: TRANSFERASE/TRANSFERASE REGULATOR Ligands: 9EM |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-06-07
Ligands: 9EM
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Crystal Structure Of Bruton Agammabulinemia Tyrosine Kinase Complexed With Bms-986142 Aka (2S)-6-Fluoro-5-[3-(8-Fluoro-1-Methyl-2,4-Dioxo-1,2,3,4-Tetrahydroquinazolin-3-Yl)-2-Methylphenyl]-2-(2-Hydroxypropan-2-Yl)-2,3,4,9-Tetrahydro-1H-Carbazole-8-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.50 Å Release Date: 2017-03-08 Classification: TRANSFERASE Ligands: 73T |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-03-08
Ligands: 73T
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Crystal Structure Of Bruton Agammaglobulinemia Tyrosine Kinase Complexed With 4-[2-Fluoro-3-(4-Oxo -3,4-Dihydroquinazolin-3-Yl)Phenyl]-7-(2-Hydroxypropan-2-Y L)-9H-Carbazole-1-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.97 Å Release Date: 2016-08-31 Classification: TRANSFERASE/TRANSFERASE inhibitor Ligands: 6MV |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-08-31
Ligands: 6MV