Search Count: 18
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Identification Of Multiple Ligand Hotspots On Sos2, Compound 9
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.40 Å Release Date: 2025-02-05 Classification: SIGNALING PROTEIN Ligands: A1ASY |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-02-05
Ligands: A1ASY
 |
Identification Of Multiple Ligand Hotspots On Sos2, Compound 6
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.82 Å Release Date: 2025-02-05 Classification: SIGNALING PROTEIN Ligands: A1ASX, DMS, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-02-05
Ligands: A1ASX, DMS, SO4
 |
Identification Of Multiple Ligand Hotspots On Sos2, Compound 2
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.79 Å Release Date: 2025-02-05 Classification: SIGNALING PROTEIN Ligands: A1ASW |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-02-05
Ligands: A1ASW
 |
Sos2 In Complex With Compound 11
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.06 Å Release Date: 2025-02-05 Classification: HYDROLASE Ligands: A1IL1 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-02-05
Ligands: A1IL1
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Crystal Structure Of Mdm2 With Brigimadlin
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.46 Å Release Date: 2024-10-02 Classification: LIGASE Ligands: G7I |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-10-02
Ligands: G7I
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Crystal Structure Of Sos1 In Complex With Compound 2
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.93 Å Release Date: 2021-03-24 Classification: PROTEIN BINDING Ligands: S2Q |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-03-24
Ligands: S2Q
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Crystal Structure Of Sos1 In Complex With Compound 4
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.72 Å Release Date: 2021-03-24 Classification: PROTEIN BINDING Ligands: IMD, S2Z |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-03-24
Ligands: IMD, S2Z
 |
Crystal Structure Of Sos1 In Complex With Compound 6
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.28 Å Release Date: 2021-03-24 Classification: PROTEIN BINDING Ligands: IMD, S3Q |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-03-24
Ligands: IMD, S3Q
 |
Crystal Structure Of Sos1 In Complex With Compound 7
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.88 Å Release Date: 2021-03-24 Classification: PROTEIN BINDING Ligands: IMD, S3T |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-03-24
Ligands: IMD, S3T
 |
Crystal Structure Of Sos1 In Complex With Compound 8
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.10 Å Release Date: 2021-03-24 Classification: PROTEIN BINDING Ligands: IMD, S3Z |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-03-24
Ligands: IMD, S3Z
 |
Crystal Structure Of Sos1 In Complex With Compound 9
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.12 Å Release Date: 2021-03-24 Classification: PROTEIN BINDING Ligands: IMD, S2W |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-03-24
Ligands: IMD, S2W
 |
Sos1 In Complex With Inhibitor Bi-3406
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.87 Å Release Date: 2020-08-26 Classification: ONCOPROTEIN Ligands: IMD, EDO, L7H |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-08-26
Ligands: IMD, EDO, L7H
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Sos1 In Complex With Inhibitor Bi-68Bs
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.92 Å Release Date: 2020-08-26 Classification: ONCOPROTEIN Ligands: IMD, LBK |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-08-26
Ligands: IMD, LBK
 |
Crystal Structure Of Mdm2 In Complex With Compound 13.
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.77 Å Release Date: 2018-12-19 Classification: LIGASE Ligands: H28, GOL, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-12-19
Ligands: H28, GOL, SO4
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Novel Spiro[3H-Indole-3,2 -Pyrrolidin]-2(1H)-One Inhibitors Of The Mdm2-P53 Interaction: Hdm2 (Mdm2) In Complex With Compound 6B
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.73 Å Release Date: 2016-11-02 Classification: LIGASE Ligands: 6SK, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-11-02
Ligands: 6SK, SO4
 |
Novel Spiro[3H-Indole-3,2 -Pyrrolidin]-2(1H)-One Inhibitors Of The Mdm2-P53 Interaction: Hdm2 (Mdm2) In Complex With Compound 14
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.64 Å Release Date: 2016-11-02 Classification: LIGASE Ligands: 6SJ, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-11-02
Ligands: 6SJ, SO4
 |
Discovery Of New Natural-Product-Inspired Spiro-Oxindole Compounds As Orally Active Inhibitors Of The Mdm2-P53 Interaction: Hdm2 (Mdm2) In Complex With Compound 6G
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.71 Å Release Date: 2016-11-02 Classification: LIGASE Ligands: GOL, SO4, 6SS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-11-02
Ligands: GOL, SO4, 6SS
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Novel Spiro[3H-Indole-3,2 -Pyrrolidin]-2(1H)-One Inhibitors Of The Mdm2-P53 Interaction: Hdm2 (Mdm2) In Complex With Compound Bi-0252
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.66 Å Release Date: 2016-11-02 Classification: LIGASE Ligands: 6ST, ZN, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-11-02
Ligands: 6ST, ZN, SO4