Search Count: 33
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Crystal Structure Of 11Beta-Hsd1 Double Mutant (L262R, F278E) Complexed With 2-(3-(1-(4-Chlorophenyl)Cyclopropyl) -[1,2,4]Triazolo[4,3-A]Pyridin-8-Yl)Propan-2-Ol
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.45 Å Release Date: 2018-12-19 Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR Ligands: NAP, HJG |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-12-19
Ligands: NAP, HJG
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Crystal Structure Of Murine 11B- Hydroxysteroiddehydrogenase Complexed With 2-(3-(1-(4- Chlorophenyl)Cyclopropyl)-[1,2,4]Triazolo[4,3-A]Pyridin-8- Yl)Propan-2-Ol
Organism: Mus musculus
Method: X-RAY DIFFRACTION Resolution:2.65 Å Release Date: 2018-12-19 Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR Ligands: NAP, HJG, SO4 |
Organism: Mus musculus
Method: X-RAY DIFFRACTION
Release Date: 2018-12-19
Ligands: NAP, HJG, SO4
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Crystal Structure Of 11Beta-Hsd1 Double Mutant (L262R, F278E) Complexed With 2-[2-(4-Fluorophenyl)-2-Adamantyl]-1-(3-Methoxyazetidin-1-Yl)Ethanone
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.35 Å Release Date: 2017-11-01 Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR Ligands: NAP, 8K4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-11-01
Ligands: NAP, 8K4
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Crystal Structure Of 11Beta-Hsd1 Double Mutant (L262R, F278E) Complexed With 1-(3-Hydroxyazetidin-1-Yl)-2-[(2S,5R)-2-(4-Fluorophenyl)-5-Methoxyadamantan-2-Yl]Ethan-1-One
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.35 Å Release Date: 2017-11-01 Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR Ligands: NAP, 8K7 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-11-01
Ligands: NAP, 8K7
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Crystal Structure Of 11Beta-Hsd1 Double Mutant (L262R, F278E) Complexed With 2-[(1R,3S,5R,7S)-2-[4-(4-Fluorophenyl)Phenyl]-6-Hydroxyadamantan-2-Yl]-1-(3- Hydroxyazetidin-1-Yl)Ethan-1-One
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.37 Å Release Date: 2017-11-01 Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR Ligands: NAP, 8KA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-11-01
Ligands: NAP, 8KA
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Crystal Structure Of 11Beta-Hsd1 Double Mutant (L262R, F278E) Complexed With 2-(2-Benzyl-6-Hydroxyadamantan-2-Yl)-1-(3-Hydroxyazetidin-1-Yl)Ethan-1-One
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.50 Å Release Date: 2017-11-01 Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR Ligands: NAP, 8KD |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-11-01
Ligands: NAP, 8KD
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Crystal Structure Of 11Beta-Hsd1 Double Mutant (L262R, F278E) Complexed With 2-[(5R,7S)-6-Hydroxy-2-Phenyladamantan-2-Yl]-1-(3-Hydroxyazetidin-1-Yl)Ethan-1-One (Bms-816336)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.07 Å Release Date: 2017-11-01 Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR Ligands: NAP, 8KG |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-11-01
Ligands: NAP, 8KG
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Crystal Structure Of Murine 11Beta- Hydroxysteroiddehydrogenase Complexed With 2-[(5R,7S)-6-Hydroxy-2-Phenyladamantan-2-Yl]-1-(3-Hydroxyazetidin-1-Yl)Ethan-1-One (Bms-816336)
Organism: Mus musculus
Method: X-RAY DIFFRACTION Resolution:2.90 Å Release Date: 2017-11-01 Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR Ligands: NAP, 8KG, SO4 |
Organism: Mus musculus
Method: X-RAY DIFFRACTION
Release Date: 2017-11-01
Ligands: NAP, 8KG, SO4
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Crystal Structure Of Death Receptor 4 (Dr4; Tnffrsf10A) Bound To Trail (Tnfsf10)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.00 Å Release Date: 2017-01-18 Classification: APOPTOSIS Ligands: ZN, CL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-01-18
Ligands: ZN, CL
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Structure Of The Extracellular Domain Of The Cd40 In Complex With Chi220 Fab
Organism: Homo sapiens, Mus musculus, homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.69 Å Release Date: 2016-06-01 Classification: IMMUNE SYSTEM/SIGNALING PROTEIN Ligands: SO4 |
Organism: Homo sapiens, Mus musculus, homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-06-01
Ligands: SO4
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Structure Of The Extracellular Domain Of The Cd40 In Complex With 3H56-5 Dab
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.79 Å Release Date: 2016-06-01 Classification: IMMUNE SYSTEM/SIGNALING PROTEIN Ligands: K |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-06-01
Ligands: K
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Structure Of The Extracellular Domain Of The Cd40 In Complex With 3H56-5 Dab
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.30 Å Release Date: 2016-06-01 Classification: IMMUNE SYSTEM/SIGNALING PROTEIN Ligands: SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-06-01
Ligands: SO4
 |
Factor Xia In Complex With The Inhibitor 4-(Aminomethyl)-~{N}-[(1~{S})-1-[4-(3-Oxidanyl-1~{H}-Indazol-5-Yl)Pyridin-2-Yl]-2-Phenyl-Ethyl]Cyclohexane-1-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.30 Å Release Date: 2016-04-13 Classification: HYDROLASE/HYDROLASE Inhibitor Ligands: 5SS, SO4, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-04-13
Ligands: 5SS, SO4, EDO
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Factor Xia In Complex With The Inhibitor Methyl ~{N}-[4-[2-[(1~{S})-1-[[4-(Aminomethyl)Cyclohexyl]Carbonylamino]-2-Phenyl-Ethyl]Pyridin-4-Yl]Phenyl]Carbamate
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.09 Å Release Date: 2016-04-13 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: 5ST, SO4, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-04-13
Ligands: 5ST, SO4, EDO
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Factor Xia In Complex With The Inhibitor 4-[(N-{(2E)-3-[5-Chloro-2-(1H-Tetrazol-1-Yl)Phenyl]Prop-2-Enoyl}-L-Phenylalanyl)Amino]Benzoic Acid
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.08 Å Release Date: 2015-12-09 Classification: Hydrolase/Hydrolase Inhibitor Ligands: 5JM, SO4, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-12-09
Ligands: 5JM, SO4, EDO
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Factor Xia In Complex With The Inhibitor N-[(1S)-1-Benzyl-2-[2-[5-Chloro-2-(Tetrazol-1-Yl)Phenyl]Ethylamino]-2-Oxo-Ethyl]-4-Hydroxy-2-Oxo-1H-Quinoline-6-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.11 Å Release Date: 2015-12-09 Classification: Hydrolase/Hydrolase Inhibitor Ligands: 7P0, SO4, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-12-09
Ligands: 7P0, SO4, EDO
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Factor Xia In Complex With The Inhibitor Methyl (4-{4-Chloro-2-[(1S)-1-({(2E)-3-[5-Chloro-2-(1H-Tetrazol-1-Yl)Phenyl]Prop-2-Enoyl}Amino)-2-Phenylethyl]-1H-Imidazol-5-Yl}Phenyl)Carbamate
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.90 Å Release Date: 2015-05-27 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: 4GR, SO4, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-05-27
Ligands: 4GR, SO4, EDO
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Factor Xia In Complex With The Inhibitor Methyl (4-{4-Chloro-2-[(1S)-1-({(2E)-3-[5-Chloro-2-(1H-Tetrazol-1-Yl)Phenyl]Prop-2-Enoyl}Amino)-3-(Morpholin-4-Yl)-3-Oxopropyl]-1H-Imidazol-5-Yl}Phenyl)Carbamate
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.60 Å Release Date: 2015-05-27 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: 4D5, SO4, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-05-27
Ligands: 4D5, SO4, EDO
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Factor Xia In Complex With The Inhibitor (2E)-N-[(1S)-1-[5-Chloro-4-(4-Hydroxy-2-Oxo-1,2-Dihydroquinolin-6-Yl)-1H-Imidazol-2-Yl]-3-(4-Methylpiperazin-1-Yl)-3-Oxopropyl]-3-[5-Chloro-2-(1H-Tetrazol-1-Yl)Phenyl]Prop-2-Enamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.20 Å Release Date: 2015-05-27 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: 4CE, SO4, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-05-27
Ligands: 4CE, SO4, EDO
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Factor Xia In Complex With The Inhibitor 1-{(1S)-1-[4-(3-Amino-1H-Indazol-6-Yl)-5-Chloro-1H-Imidazol-2-Yl]-2-Phenylethyl}-3-[2-(Aminomethyl)-5-Chlorobenzyl]Urea
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.40 Å Release Date: 2015-02-18 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: 3Y3, SO4, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-02-18
Ligands: 3Y3, SO4, EDO