Search Count: 34
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Crystal Structure Of Non-Classical Ts Inhibitor 2 In Complex With Toxoplasma Gondii Ts-Dhfr
Organism: Toxoplasma gondii
Method: X-RAY DIFFRACTION Resolution:2.79 Å Release Date: 2014-08-06 Classification: OXIDOREDUCTASE, TRANSFERASE Ligands: UMP, 04J, NDP, 1UE |
Organism: Toxoplasma gondii
Method: X-RAY DIFFRACTION
Release Date: 2014-08-06
Ligands: UMP, 04J, NDP, 1UE
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Crystal Structure Of Non-Classical Ts Inhibitor 3 In Complex With Toxoplasma Gondii Ts-Dhfr
Organism: Toxoplasma gondii
Method: X-RAY DIFFRACTION Resolution:3.26 Å Release Date: 2014-08-06 Classification: OXIDOREDUCTASE, TRANSFERASE/INHIBITOR Ligands: UMP, 1UG, FOL, NDP |
Organism: Toxoplasma gondii
Method: X-RAY DIFFRACTION
Release Date: 2014-08-06
Ligands: UMP, 1UG, FOL, NDP
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Hdhfr-Oag Binary Complex
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.35 Å Release Date: 2014-01-29 Classification: OXIDOREDUCTASE Ligands: OAG, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-01-29
Ligands: OAG, SO4
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Pcdhfr K37S/F69N Double Mutant Tmp Nadph Ternary Complex
Organism: Pneumocystis jirovecii
Method: X-RAY DIFFRACTION Resolution:1.75 Å Release Date: 2013-05-29 Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR Ligands: TOP, NDP |
Organism: Pneumocystis jirovecii
Method: X-RAY DIFFRACTION
Release Date: 2013-05-29
Ligands: TOP, NDP
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Pcdhfr-Nadph-270
Organism: Pneumocystis carinii
Method: X-RAY DIFFRACTION Resolution:1.54 Å Release Date: 2013-05-29 Classification: OXIDOREDUCTASE/Inhibitor Ligands: IXE, NDP |
Organism: Pneumocystis carinii
Method: X-RAY DIFFRACTION
Release Date: 2013-05-29
Ligands: IXE, NDP
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Pcdhfr-269 F69N Variant
Organism: Pneumocystis carinii
Method: X-RAY DIFFRACTION Resolution:1.70 Å Release Date: 2013-05-29 Classification: OXIDOREDUCTASE/Inhibitor Ligands: NDP, IXF |
Organism: Pneumocystis carinii
Method: X-RAY DIFFRACTION
Release Date: 2013-05-29
Ligands: NDP, IXF
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Pcdhfr-268-K37S-N69F Variant
Organism: Pneumocystis carinii
Method: X-RAY DIFFRACTION Resolution:1.70 Å Release Date: 2013-05-15 Classification: OXIDOREDUCTASE/Inhibitor Ligands: NDP, IXG |
Organism: Pneumocystis carinii
Method: X-RAY DIFFRACTION
Release Date: 2013-05-15
Ligands: NDP, IXG
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Hdhfr Double Mutant Q35S/N64F Trimethoprim Binary Complex
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.92 Å Release Date: 2011-09-28 Classification: OXIDOREDUCTASE Ligands: TOP, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-09-28
Ligands: TOP, SO4
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Human Dihydrofolate Reductase Q35K/N64F Double Mutant Binary Complex With Trimethoprim
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.53 Å Release Date: 2011-09-28 Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR Ligands: TOP, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-09-28
Ligands: TOP, SO4
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Structural And Kinetic Data For Antifolate Interactions Against Pneumocystis Jirovecii, Pneumocystis Carinii And Human Dihydrofolate Reductase And Thier Active Site Mutants
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.70 Å Release Date: 2011-08-03 Classification: OXIDOREDUCTASE/INHIBITOR Ligands: OAG, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-08-03
Ligands: OAG, SO4
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Structural, Computational And Kinetic Data For Antifolate Interactions Against Pneumocystis Jirovecii, Pneumocystis Carinii And Human Dihydrofolate Reductase And Their Active Site Mutants
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.00 Å Release Date: 2011-01-05 Classification: OXIDOREDUCTASE Ligands: OAG, NDP, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-01-05
Ligands: OAG, NDP, SO4
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Alternate Binding Modes Observed For The E- And Z-Isomers Of 2,4-Diaminofuro[2,3D]Pyrimidines As Ternary Complexes With Nadph And Mouse Dihydrofolate Reductase
Organism: Mus musculus
Method: X-RAY DIFFRACTION Resolution:1.60 Å Release Date: 2009-10-13 Classification: OXIDOREDUCTASE Ligands: NDP, 51P |
Organism: Mus musculus
Method: X-RAY DIFFRACTION
Release Date: 2009-10-13
Ligands: NDP, 51P
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Alternate Binding Modes Observed For The E- And Z-Isomers Of 2,4-Diaminofuro[2,3-D]Pyrimidines As Ternary Complexes With Nadph And Mouse Dihydrofolate Reductase
Organism: Mus musculus
Method: X-RAY DIFFRACTION Resolution:2.05 Å Release Date: 2009-10-13 Classification: OXIDOREDUCTASE Ligands: D09, NDP |
Organism: Mus musculus
Method: X-RAY DIFFRACTION
Release Date: 2009-10-13
Ligands: D09, NDP
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Correlations Of Human Dihydrofolate Reductase With Structural Data For Human Active Site Mutant Enzyme Complexes
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.45 Å Release Date: 2009-08-18 Classification: OXIDOREDUCTASE Ligands: DH1, NDP, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2009-08-18
Ligands: DH1, NDP, SO4
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Human Dihydrofolate Reductase Structural Data With Active Site Mutant Enzyme Complexes
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.01 Å Release Date: 2009-08-18 Classification: OXIDOREDUCTASE Ligands: DH1, NDP, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2009-08-18
Ligands: DH1, NDP, SO4
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Structural Data For Human Active Site Mutant Enzyme Complexes
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.90 Å Release Date: 2009-08-18 Classification: OXIDOREDUCTASE Ligands: DH1, NDP, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2009-08-18
Ligands: DH1, NDP, SO4
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Correlations Of Inhibitor Kinetics For Pneumocystis Jirovecii And Human Dihydrofolate Reductase With Structural Data For Human Active Site Mutant Enzyme Complexes
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.23 Å Release Date: 2009-08-18 Classification: OXIDOREDUCTASE Ligands: DH1, NDP |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2009-08-18
Ligands: DH1, NDP
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Human Dihydrofolate Reductase Complexed With Nadph And 2,4-Diamino-5-(1-O-Carboranylmethyl)-6-Methylpyrimidine, A Novel Boron Containing, Nonclassical Antifolate
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.40 Å Release Date: 2007-04-10 Classification: OXIDOREDUCTASE Ligands: NDP, 34B, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2007-04-10
Ligands: NDP, 34B, GOL
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Human Dihydrofolate Reductase Complexed With Nadph And 2,4-Diamino-5-((7,8-Dicarbaundecaboran-7-Yl)Methyl)-6-Methylpyrimidine, A Novel Boron Containing, Nonclassical Antifolate
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.50 Å Release Date: 2007-04-10 Classification: OXIDOREDUCTASE Ligands: NDP, 39B, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2007-04-10
Ligands: NDP, 39B, GOL
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Structure Determination Of Tetrahydroquinazoline Antifolates In Complex With Human And Pneumocystis Carinii Dihydrofolate Reductase: Correlations Of Enzyme Selectivity And Stereochemistry
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.50 Å Release Date: 2004-03-30 Classification: OXIDOREDUCTASE Ligands: SO4, TQD |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2004-03-30
Ligands: SO4, TQD