Search Count: 30
 |
Structure Of Crbn:Ikzf2:Compound 15
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.60 Å Release Date: 2025-09-03 Classification: IMMUNE SYSTEM Ligands: A1CBH, ZN |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-09-03
Ligands: A1CBH, ZN
 |
Structure Of Crbn:Ikzf2:Compound 35
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.34 Å Release Date: 2025-09-03 Classification: IMMUNE SYSTEM Ligands: A1CBG, ZN |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-09-03
Ligands: A1CBG, ZN
 |
Structure Of Ikzf2:Crbn:Compound 5 Ternary Structure
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.86 Å Release Date: 2025-07-09 Classification: IMMUNE SYSTEM Ligands: A1CAC, ZN |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-07-09
Ligands: A1CAC, ZN
 |
Structure Of Crbn Tbd Bound To Compound C1
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.42 Å Release Date: 2025-05-28 Classification: IMMUNE SYSTEM Ligands: A1CAV, ZN |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-05-28
Ligands: A1CAV, ZN
 |
Structure Of Crbn Tbd Bound To Compound C3
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.61 Å Release Date: 2025-05-28 Classification: IMMUNE SYSTEM Ligands: A1CAW, ZN |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-05-28
Ligands: A1CAW, ZN
 |
Pvtx-405: A Potent, Highly Selective, And Orally Efficacious Molecular Glue Degrader Of Ikzf2 For Cancer Immunotherapy
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.69 Å Release Date: 2025-05-14 Classification: TRANSCRIPTION Ligands: A1A8N, ZN |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-05-14
Ligands: A1A8N, ZN
 |
Discovery Of Potent, Highly Selective And Efficacious Smarca2 Degraders - Compound 11
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.26 Å Release Date: 2024-12-18 Classification: TRANSCRIPTION Ligands: A1BF5, ZN |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-12-18
Ligands: A1BF5, ZN
 |
Discovery Of Potent, Highly Selective And Efficacious Smarca2 Degraders - Compound 13
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.71 Å Release Date: 2024-12-18 Classification: TRANSCRIPTION Ligands: A1A1O, ZN, ACT |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-12-18
Ligands: A1A1O, ZN, ACT
 |
Discovery Of Potent, Highly Selective And Efficacious Smarca2 Degraders - Compound 6
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.96 Å Release Date: 2024-12-18 Classification: TRANSCRIPTION Ligands: A1A1P, ZN, ACT |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-12-18
Ligands: A1A1P, ZN, ACT
 |
Factor Viia In Complex With The Inhibitor 3-{[(2R)-17-Ethyl-4-Methyl-3,12-Dioxo-7-[(Propan-2-Yl)Sulfonyl]-13-Oxa-4,11-Diazatricyclo[14.2.2.1~6,10~]Henicosa-1(18),6(21),7,9,16,19-Hexaen-2-Yl]Amino}Benzamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.30 Å Release Date: 2017-05-10 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: 82J, CA, SO4, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-05-10
Ligands: 82J, CA, SO4, GOL
 |
Factor Viia In Complex With The Inhibitor (5R)-5-[(1-Aminoisoquinolin-6-Yl)Amino]-19-(Cyclopropylsulfonyl)-3-Methyl-13-Oxa-3,15-Diazatricyclo[14.3.1.1~6,10~]Henicosa-1(20),6(21),7,9,16,18-Hexaene-4,14-Dione
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.90 Å Release Date: 2017-02-01 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: 7KQ, CA, SO4, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-02-01
Ligands: 7KQ, CA, SO4, GOL
 |
Factor Viia In Complex With The Inhibitor (11R)-11-[(1-Aminoisoquinolin-6-Yl)Amino]-16-(Cyclopropylsulfonyl)-13-Methyl-2,13-Diazatricyclo[13.3.1.1~6,10~]Icosa-1(19),6(20),7,9,15,17-Hexaene-3,12-Dione
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.85 Å Release Date: 2017-02-01 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: 7KR, CA, SO4, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-02-01
Ligands: 7KR, CA, SO4, GOL
 |
Factor Viia In Complex With The Inhibitor (5R,11R)-11-[(1-Amino-4-Fluoroisoquinolin-6-Yl)Amino]-16-(Cyclopropylsulfonyl)-7-(2,2-Difluoroethoxy)-5,13-Dimethyl-2,13-Diazatricyclo[13.3.1.1~6,10~]Icosa-1(19),6(20),7,9,15,17-Hexaene-3,12-Dione
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.90 Å Release Date: 2017-02-01 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: 7KS, CA, SO4, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-02-01
Ligands: 7KS, CA, SO4, GOL
 |
Factor Viia In Complex With The Inhibitor 1-[(2R,15R)-2-[(1-Amino-4-Fluoroisoquinolin-6-Yl)Amino]-4,15,20-Trimethyl-3,12-Dioxo-13-Oxa-4,11-Diazatricyclo[14.2.2.1~6,10~]Henicosa-1(18),6,8,10(21),16,19-Hexaen-7-Yl] Cyclobutane-1-Carboxylic Acid
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.82 Å Release Date: 2016-09-28 Classification: Hydrolase/Hydrolase Inhibitor Ligands: 70D, CA, SO4, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-09-28
Ligands: 70D, CA, SO4, GOL
 |
Factor Viia In Complex With The Inhibitor 1-[(2R,15R)-2-[(1-Amino-4-Fluoroisoquinolin-6-Yl)Amino]-4,15,17-Trimethyl-3,12-Dioxo-13-Oxa-4,11-Diazatricyclo[14.2.2.1~6,10~]Henicosa-1(18),6(21),7,9,16,19-Hexaen-7-Yl]Cyclohexane-1-Carboxylic Acid
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.79 Å Release Date: 2016-09-28 Classification: Hydrolase/Hydrolase inhibitor Ligands: 70C, CA, SO4, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-09-28
Ligands: 70C, CA, SO4, GOL
 |
Factor Viia In Complex With The Inhibitor (2R,15R)-2-[(1-Aminoisoquinolin-6-Yl)Amino]-4,15,17-Trimethyl-7-[1-(1H-Tetrazol-5-Yl)Cyclopropyl]-13-Oxa-4,11-Diazatricyclo[14.2.2.1~6,10~]Henicosa-1(18),6(21),7,9,16,19-Hexaene-3,12-Dione
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.73 Å Release Date: 2016-09-28 Classification: Hydrolase/Hydrolase Inhibitor Ligands: 70A, CA, SO4, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-09-28
Ligands: 70A, CA, SO4, GOL
 |
Factor Viia In Complex With The Inhibitor (2R,15R)-2-[(1-Aminoisoquinolin-6-Yl)Amino]-8-Fluoro-7-Hydroxy-4,15,17-Trimethyl-13-Oxa-4,11-Diazatricyclo[14.2.2.1~6,10~]Henicosa-1(18),6(21),7,9,16,19-Hexaene-3,12-Dione
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.06 Å Release Date: 2016-06-22 Classification: Hydrolase/Hydrolase inhibitor Ligands: 67O, CA, SO4, MES |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-06-22
Ligands: 67O, CA, SO4, MES
 |
Factor Viia In Complex With The Inhibitor N-{3-[(2R)-1-{(2R)-2-[(1-Aminoisoquinolin-6-Yl)Amino]-2-Phenylacetyl}Pyrrolidin-2-Yl]-4-(Propan-2-Ylsulfonyl)Phenyl}Acetamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.60 Å Release Date: 2015-07-22 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: 4T0, CA, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-07-22
Ligands: 4T0, CA, SO4
 |
Factor Viia In Complex With The Inhibitor (2R)-2-[(1-Aminoisoquinolin-6-Yl)Amino]-4,11-Diazatricyclo[14.2.2.1~6,10~]Henicosa-1(18),6(21),7,9,16,19-Hexaene-3,12-Dione
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.06 Å Release Date: 2015-07-22 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: 4T1, CA, SO4, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-07-22
Ligands: 4T1, CA, SO4, GOL
 |
Factor Viia In Complex With The Inhibitor 4-{[(R)-[5-Ethoxy-2-Fluoro-3-(Propan-2-Yloxy)Phenyl](4-Phenyl-1H-Imidazol-2-Yl)Methyl]Amino}Benzenecarboximidamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.07 Å Release Date: 2015-04-29 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: 4JY, CA, SO4, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-04-29
Ligands: 4JY, CA, SO4, GOL