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9HQ0 image
Sarm1 Tir Domain In Complex With Compound 7-Adpr
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:2.13 Å Release Date: 2025-12-24
Classification: HYDROLASE
Ligands: A1IW3, EDO

9HQF image
Sarm1 Tir Domain In Complex With Compound 7-Adpr
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:1.73 Å Release Date: 2025-12-24
Classification: HYDROLASE
Ligands: A1IWL

9HQH image
Sarm1 Tir Domain In Complex With Compound 28-Adpr
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:1.99 Å Release Date: 2025-12-24
Classification: HYDROLASE
Ligands: A1IWN

7FVU image
Crystal Structure Of Human Fabp4 In Complex With 2-[2-(Benzothiophen-3-Yl)-2,3-Dihydrobenzothiophene-3-Carbonyl]Benzoic Acid

7FVV image
Crystal Structure Of Human Fabp4 In Complex With (1S,2R)-2-[(5-Carbamoyl-3-Ethoxycarbonyl-4-Methyl-2-Thienyl)Carbamoyl]Cyclohexanecarboxylic Acid

7FVW image
Crystal Structure Of Human Fabp4 In Complex With 2-[2-(3-Chlorophenyl)Ethyl]-1,3-Thiazole-4-Carboxylic Acid

7FVX image
Crystal Structure Of Human Fabp4 In Complex With 4-(1-Methyl-2-Phenylindol-3-Yl)Cyclohexane-1-Carboxylic Acid, I.E. Smiles C1Ccc2C(C1)C(=C(N2C)C1Ccccc1)[C@@H]1Cc[C@@H](Cc1)C(=O)O With Ic50=0.048 Microm

7FVY image
Crystal Structure Of Human Fabp4 In Complex With 2-[(3-Chlorophenyl)Methyl]-1,3-Thiazole-4-Carboxylic Acid

7FVZ image
Crystal Structure Of Human Fabp4 In Complex With (E)-6-(5-Methoxy-3,6,7-Trimethyl-1,2-Benzoxazol-4-Yl)-4-Methyl-Hex-4-Enoic Acid

7FW0 image
Crystal Structure Of Human Fabp4 In Complex With 3-Methyl-2-(2,4,5-Trichlorophenyl)Sulfanylbutanoic Acid, I.E. Smiles C1(C(Cc(C(C1)Cl)S[C@@H](C(=O)O)C(C)C)Cl)Cl With Ic50=3.5 Microm

7FW1 image
Crystal Structure Of Human Fabp4 In Complex With 2-Cyclopentyl-4-(4-Fluorophenyl)-6-[1-(Methoxymethyl)Cyclopentyl]-3-Methyl-5-(1H-Tetrazol-5-Yl)Pyridine, I.E. Smiles C1(C(Nc(C(C1C1Ccc(Cc1)F)C1=Nn=Nn1)C1(Cccc1)Coc)C1Cccc1)C With Ic50=0.0153077 Microm

7FW2 image
Crystal Structure Of Human Fabp4 In Complex With 5-[(4-Chlorophenoxy)Methyl]-4-Prop-2-Enyl-1,2,4-Triazole-3-Thiol, I.E. Smiles N1(C(=Nn=C1Coc1Ccc(Cl)Cc1)S)Cc=C With Ic50=0.833 Microm

7FW3 image
Crystal Structure Of Human Fabp4 In Complex With 7-(4-Chlorophenyl)-1,2,3,4-Tetrahydronaphthalene-1-Carboxylic Acid, I.E. Smiles C12C(Ccc(C2)C2Ccc(Cc2)Cl)Ccc[C@H]1C(=O)O With Ic50=3.3 Microm

7FW4 image
Crystal Structure Of Human Fabp4 Soaked With Glycerol

7FW5 image
Crystal Structure Of Human Fabp4 With Active Site Mutated To That Of Fabp3 In Complex With Palmitate

7FW6 image
Crystal Structure Of Human Fabp4 In Complex With 2-[(3-Chlorophenoxy)Methyl]-4-Phenoxycyclohexane-1-Carboxylic Acid, I.E. Smiles O(C1Ccccc1)[C@H]1Cc[C@H]([C@H](C1)Coc1Cccc(C1)Cl)C(=O)O With Ic50=0.259424 Microm

7FW7 image
Crystal Structure Of Human Fabp4 In Complex With 2-[(3-Chloro-4-Fluorophenyl)Carbamoyl]Cyclohexane-1-Carboxylic Acid, I.E. Smiles C(=O)([C@H]1[C@@H](C(=O)O)Cccc1)Nc1Cc(C(Cc1)F)Cl With Ic50=12.0427 Microm

7FW8 image
Crystal Structure Of Human Fabp4 Binding Site Mutated To That Of Fabp3 In Complex With 6-Chloro-2-Methyl-4-Phenylquinoline-3-Carboxylic Acid, I.E. Smiles C1(C(C2C(Nc1C)Ccc(C2)Cl)C1Ccccc1)C(=O)O With Ic50=0.275 Microm

7FW9 image
Crystal Structure Of Human Fabp4 In Complex With 2-[(3-Ethoxycarbonyl-4,5,6,7-Tetrahydro-1-Benzothiophen-2-Yl)Carbamoyl]Cyclopentene-1-Carboxylic Acid, I.E. Smiles C1Ccc2=C(C1)C(=C(S2)Nc(=O)C1=C(C(=O)O)Ccc1)C(=O)Occ With Ic50=1.1 Microm

7FWA image
Crystal Structure Of Human Fabp4 In Complex With 5-[(4-Chloroanilino)Methyl]-2-Phenyl-4H-[1,2,4]Triazolo[1,5-A]Pyrimidin-7-One, I.E. Smiles N12C(=Nc(=N1)C1Ccccc1)Nc(=Cc2=O)Cnc1Ccc(Cl)Cc1 With Ic50=0.683 Microm
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