Search Count: 21
 |
Crystal Structure Of Irak4-Hsa Complexed With N-[(2R)-2-Fluoro-3-Hydroxy-3-Methylbutyl]-6-[(5-Fluoropyri-Yl)Amino]-4-[(Propan-2-Yl)Amino]Pyridine-3-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.89 Å Release Date: 2025-02-12 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: ZVD, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-02-12
Ligands: ZVD, SO4
 |
Crystal Structure Of Irak4-Hsa Complexed With Bms-986126; 6-((5-Cyano-2-Pyrimidinyl)Amino)-N-((2R)-2-Fluoro-3-Hydroxhylbutyl)-4-(Isopropylamino)Nicotinamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.69 Å Release Date: 2025-02-12 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: ZVG, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-02-12
Ligands: ZVG, SO4
 |
Crystal Structure Of Irak4-Hsa Complexed With Bms-986147; 6-{5-Cyano-1H-Pyrazolo[3,4-B]Pyridin-1-Yl}-N-[(2R)-2-Fluorroxy-3-Methylbutyl]-4-[(Propan-2-Yl)Amino]Pyridine-3-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.76 Å Release Date: 2025-02-12 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: SO4, ZVA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-02-12
Ligands: SO4, ZVA
 |
Irak4 In Complex With Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.19 Å Release Date: 2020-11-25 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: EXF, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-11-25
Ligands: EXF, SO4
 |
Crystal Structure Of Interleukin-1 Receptor-Associated Kinase 4 (Irak4-Wt) Complex With A Nicotinamide Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.07 Å Release Date: 2020-06-24 Classification: TRANSFERASE/TRANSFERASE Inhibitor Ligands: R7S, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-06-24
Ligands: R7S, SO4
 |
Crystal Structure Of Tyrosine Kinase 2 Jh2 (Pseudo Kinase Domain) Complexed With Compound-11 Aka 6-Cyclopropaneamido-4-{[2-Methoxy-3-(1-Methyl-1H-1,2,4-Tri Azol-3-Yl)Phenyl]Amino}-N-(?H?)Methylpyridazine-3-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.35 Å Release Date: 2019-07-31 Classification: TRANSFERASE Ligands: LB7, CL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-07-31
Ligands: LB7, CL
 |
Crystal Structure Of Tyrosine Kinase 2 Jh2 (Pseudo Kinase Domain) Complexed With Compound_29 Aka 6-[(5-Fluoro-4-Meth Ylpyridin-2-Yl)Amino]-4-({2-Methoxy-3-[(Pyridin-2-Ylmethyl )Carbamoyl]Phenyl}Amino)-N-Methylpyridine-3-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.11 Å Release Date: 2019-07-31 Classification: TRANSFERASE Ligands: LB4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-07-31
Ligands: LB4
 |
Crystal Structure Of Tyrosine Kinase 2 Jh2 (Pseudo Kinase Domain) Complexed With Compound_12 Aka 4-[(2-Methanesulfonylphenyl)Amino]-N-(H3)Methyl-6-[(Pyridin-2- Yl)Amino]Pyridazine-3-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.56 Å Release Date: 2019-07-31 Classification: TRANSFERASE Ligands: LAJ, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-07-31
Ligands: LAJ, SO4
 |
Crystal Structure Of Mripk3 Complexed With N-(3-Fluoro-4-{1H-Pyrrolo[2,3-B]Pyridin-4-Yloxy}Phenyl)-1-(4-Fluorophenyl)-2-Oxo-1,2-Dihydropyridine-3-Carboxamide
Organism: Mus musculus
Method: X-RAY DIFFRACTION Resolution:2.10 Å Release Date: 2019-07-17 Classification: TRANSFERASE Ligands: 1FN |
Organism: Mus musculus
Method: X-RAY DIFFRACTION
Release Date: 2019-07-17
Ligands: 1FN
 |
Crystal Structure Of Jak3 Kinase Domain In Complex With A Pyrrolopyridazine Carboxamide Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.33 Å Release Date: 2019-05-22 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: Z3A |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-05-22
Ligands: Z3A
 |
Crystal Structure Of Irak-4 With A 4,6-Diaminonicotinamide Inhibitor (Compound Number 4)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.90 Å Release Date: 2017-10-11 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 9YY |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-10-11
Ligands: 9YY
 |
Crystal Structure Of Irak-4 With A 4,6-Diaminonicotinamide Inhibitor (Compound Number 9)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.25 Å Release Date: 2017-10-11 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 9YS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-10-11
Ligands: 9YS
 |
Crystal Structure Of Jak3 Kinase Domain With A 4,6-Diaminonicotinamide Inhibitor (Compound Number 7)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.61 Å Release Date: 2017-10-11 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 9YV |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-10-11
Ligands: 9YV
 |
The Jak3 Kinase Domain In Complex With A Covalent Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.48 Å Release Date: 2017-10-04 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 9Z4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-10-04
Ligands: 9Z4
 |
Crystal Structure Of Jak3 Kinase Domain In Complex With A Pyrrolopyridazine Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.65 Å Release Date: 2017-05-31 Classification: TRANSFERASE/INHIBITOR Ligands: 9J4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-05-31
Ligands: 9J4
 |
Crystal Structure Of Janus Kinase 2 In Complex With N,N-Dicyclopropyl-10-Ethyl-7-[(3-Methoxypropyl)Amino] -3-Methyl-3,5,8,10-Tetraazatricyclo[7.3.0.0,6] Dodeca-1(9),2(6),4,7,11-Pentaene-11-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.38 Å Release Date: 2015-08-26 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 50Y |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-08-26
Ligands: 50Y
 |
Crystal Structure Of Janus Kinase 2 In Complex With N,N-Dicyclopropyl-7-[(Dimethyl-1,3-Thiazol-2-Yl)Amino]-10-Ethyl-3-Methyl-3,5,8,10-Tetraazatricyclo[7.3.0.02,6] Dodeca-1(9),2(6),4,7,11-Pentaene-11-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.45 Å Release Date: 2015-08-26 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 50W |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-08-26
Ligands: 50W
 |
Crystal Structure Of Janus Kinase 2 In Complex With N,N-Dicyclopropyl-10-[(2S)-2,3-Dihydroxypropyl]-3-Methyl-7-(Methylamino)-3,5,8,10-Tetraazatricyclo [7.3.0.02,6]Dodeca-1(9),2(6),4,7,11-Pentaene-11-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.50 Å Release Date: 2015-08-26 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 50O |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-08-26
Ligands: 50O
 |
Crystal Structure Of Tyrosine Kinase 2 Jh2 (Pseudo Kinase Domain) Complexed With Bms-066 Aka 2-Methoxy-N-({6-[3-Methyl-7-(Methylamino)-3,5,8,10-Tetraazatricyclo[7.3.0.0, 6]Dodeca-1(9),2(6),4,7,11-Pentaen-11-Yl]Pyridin-2-Yl}Methy L)Acetamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.80 Å Release Date: 2015-03-18 Classification: TRANSFERASE/INHIBITOR Ligands: 3SM, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-03-18
Ligands: 3SM, SO4
 |
Crystal Structure Of Jak3 Kinase Domain In Complex With A Pyrrolopyridazine Carboxamide Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.69 Å Release Date: 2014-12-24 Classification: TRANSFERASE/INHIBITOR Ligands: 3QX |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-12-24
Ligands: 3QX