Search Count: 24
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Ppiase In Complex With A Non-Phosphate Small Molecule Inhibitor.
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.75 Å Release Date: 2014-08-20 Classification: ISOMERASE/ISOMERASE INHIBITOR Ligands: 39X, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-08-20
Ligands: 39X, GOL
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Crystal Structure Of The Human P21-Activated Kinase 4 In Complex With (S)-N-(5-(3-Benzyl-1-Methylpiperazine-4-Carbonyl)-6,6-Dimethyl-1,4,5, 6-Tetrahydropyrrolo(3,4-C)Pyrazol-3-Yl)-3-Phenoxybenzamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.20 Å Release Date: 2012-06-06 Classification: TRANSFERASE Ligands: N53, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2012-06-06
Ligands: N53, GOL
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Hdhfr Double Mutant Q35S/N64F Trimethoprim Binary Complex
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.92 Å Release Date: 2011-09-28 Classification: OXIDOREDUCTASE Ligands: TOP, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-09-28
Ligands: TOP, SO4
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Human Dihydrofolate Reductase Q35K/N64F Double Mutant Binary Complex With Trimethoprim
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.53 Å Release Date: 2011-09-28 Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR Ligands: TOP, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-09-28
Ligands: TOP, SO4
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Design, Synthesis, Biological Evaluation And X-Ray Crystal Structures Of Novel Classical 6,5,6-Tricyclicbenzo[4,5]Thieno[2,3-D]Pyrimidines As Dual Thymidylate Synthase And Dihydrofolate Reductase Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.35 Å Release Date: 2011-05-25 Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR Ligands: 3TZ, NDP, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-05-25
Ligands: 3TZ, NDP, SO4
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Design, Synthesis, Biological Evaluation And X-Ray Crystal Structure Of Novel Classical 6,5,6-Tricyclicbenzo[4,5]Thieno[2,3-D]Pyrimidines As Dual Thymidylate Synthase And Dihydrofolate Reductase Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.35 Å Release Date: 2011-05-25 Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR Ligands: NDP, 3TU, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-05-25
Ligands: NDP, 3TU, SO4
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Preferential Selection Of Isomer Binding From Chiral Mixtures: Alternate Binding Modes Observed For The E- And Z-Isomers Of A Series Of 5-Substituted 2,4-Diaminofuro-2,3-D]Pyrimidines As Ternary Complexes With Nadph And Human Dihydrofolate Reductase
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.35 Å Release Date: 2010-12-15 Classification: OXIDOREDUCTASE Ligands: NDP, D2D |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2010-12-15
Ligands: NDP, D2D
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Preferential Selection Of Isomer Binding From Chiral Mixtures: Alernate Binding Modes Observed Fro The E- And Z-Isomers Of A Series Of 5-Substituted 2,4-Diaminofuro[2,3-D]Pyrimidines As Ternary Complexes With Nadph And Human Dihydrofolate Reductase
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.90 Å Release Date: 2010-12-15 Classification: OXIDOREDUCTASE Ligands: NDP, D2H, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2010-12-15
Ligands: NDP, D2H, SO4
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Perferential Selection Of Isomer Binding From Chiral Mixtures: Alternate Binding Modes Observed For The E- And Z-Isomers Of A Series Of 5-Substituted 2,4-Diaminofuro[2,3-D]Pyrimidines As Ternary Complexes With Nadph And Human Dihydrofolate Reductase
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.35 Å Release Date: 2010-12-01 Classification: OXIDOREDUCTASE Ligands: D2B, SO4, NDP |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2010-12-01
Ligands: D2B, SO4, NDP
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Perferential Selection Of Isomer Binding From Chiral Mixtures: Alternate Binding Modes Observed For The E- And Z-Isomers Of A Series Of 5-Substituted 2,4-Diaminofuro[2,3-D]Pyrimidines As Ternary Complexes With Nadph And Human Dihydrofolate Reductase
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.35 Å Release Date: 2010-12-01 Classification: OXIDOREDUCTASE Ligands: NDP, SO4, D2D |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2010-12-01
Ligands: NDP, SO4, D2D
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Preferential Selection Of Isomer Binding From Chiral Mixtures: Alternate Binding Modes Observed For The E-And Z-Isomers Of A Series Of 5-Substituted 2,4-Diaminofuro[2M,3-D]Pyrimidines As Ternary Complexes With Nadph And Human Dihydrofolate Reductase
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.70 Å Release Date: 2010-12-01 Classification: OXIDOREDUCTASE Ligands: NDP, D2E, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2010-12-01
Ligands: NDP, D2E, SO4
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Preferential Selection Of Isomer Binding From Chiral Mixtures: Alternate Binding Modes Observed For The E- And Z-Isomers Of A Series Of 5-Substituted 2,4-Diaminofuro[2,3-D]Pyrimidines As Ternary Complexes With Nadph And Human Dihydrofolate Reductase
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.90 Å Release Date: 2010-12-01 Classification: OXIDOREDUCTASE Ligands: D2F, NDP, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2010-12-01
Ligands: D2F, NDP, SO4
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Crystal Structure Of The Human P21-Activated Kinase 4 In Complex With Pf-03758309
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.10 Å Release Date: 2010-05-19 Classification: TRANSFERASE Ligands: GOL, 7KC |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2010-05-19
Ligands: GOL, 7KC
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Human Dihydrofolate Reductase Q35K Mutant Inhibitor Complex
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.53 Å Release Date: 2009-09-29 Classification: OXIDOREDUCTASE Ligands: GHW, NDP |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2009-09-29
Ligands: GHW, NDP
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Design, Synthesis, And X-Ray Crystal Structure Of Classical And Nonclassical 2-Amino-4-Oxo-5-Substituted-6-Thieno[2,3-D]Pyrimidines As Dual Thymidylate Synthase And Dihydrofolate Reductase Inhibitors And As Potential Antitumor Agenst
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.30 Å Release Date: 2009-09-22 Classification: OXIDOREDUCTASE Ligands: GHC, NDP, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2009-09-22
Ligands: GHC, NDP, SO4
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Human Dihydrofolate Reductase Q35K/N64F Double Mutant Inhibitor Complex
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.30 Å Release Date: 2009-09-22 Classification: OXIDOREDUCTASE Ligands: GHC, NDP, GOL, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2009-09-22
Ligands: GHC, NDP, GOL, SO4
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Human Dihydrofolate Reductase Inhibitor Complex
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.24 Å Release Date: 2009-09-22 Classification: OXIDOREDUCTASE Ligands: GHW, NDP, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2009-09-22
Ligands: GHW, NDP, SO4
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Structure-Based Design Of Novel Pin1 Inhibitors (I)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.85 Å Release Date: 2009-09-22 Classification: ISOMERASE |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2009-09-22
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Structure-Based Design Of Novel Pin1 Inhibitors (I)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.00 Å Release Date: 2009-09-22 Classification: ISOMERASE Ligands: J9Z |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2009-09-22
Ligands: J9Z
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Structure-Based Design Of Novel Pin1 Inhibitors (I)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.86 Å Release Date: 2009-09-22 Classification: ISOMERASE Ligands: J8Z |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2009-09-22
Ligands: J8Z