Search Count: 51
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Highly Optimized Cns Penetrant Inhibitors Of Egfr Exon20 Insertion Mutations
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.42 Å Release Date: 2025-02-12 Classification: SIGNALING PROTEIN Ligands: A1IZ7 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-02-12
Ligands: A1IZ7
 |
Highly Optimized Cns Penetrant Inhibitors Of Egfr Exon20 Insertion Mutations
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.91 Å Release Date: 2025-02-12 Classification: SIGNALING PROTEIN Ligands: A1IZ8, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-02-12
Ligands: A1IZ8, SO4
 |
Highly Optimized Cns Penetrant Inhibitors Of Egfr Exon20 Insertion Mutations
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.90 Å Release Date: 2025-02-12 Classification: SIGNALING PROTEIN Ligands: A1IZ9 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-02-12
Ligands: A1IZ9
 |
Highly Optimized Cns Penetrant Inhibitors Of Egfr Exon20 Insertion Mutations
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.22 Å Release Date: 2025-02-12 Classification: SIGNALING PROTEIN Ligands: Q6K, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-02-12
Ligands: Q6K, SO4
 |
Highly Optimized Cns Penetrant Inhibitors Of Egfr Exon20 Insertion Mutations. Compound 51 Bound To Egfrinsnpg [V948R]
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.45 Å Release Date: 2025-02-05 Classification: SIGNALING PROTEIN Ligands: A1IUK |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-02-05
Ligands: A1IUK
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Optimisation Of Potent, Efficacious, Selective And Blood-Brain Barrier Penetrating Inhibitors Targeting Egfr Exon20 Insertion Mutations
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.44 Å Release Date: 2024-11-06 Classification: SIGNALING PROTEIN Ligands: A1H7N, IOD |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-11-06
Ligands: A1H7N, IOD
 |
Optimisation Of Potent, Efficacious, Selective And Blood-Brain Barrier Penetrating Inhibitors Targeting Egfr Exon20 Insertion Mutations
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.02 Å Release Date: 2024-10-16 Classification: SIGNALING PROTEIN Ligands: A1H7O |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-10-16
Ligands: A1H7O
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Irak4 In Complex With Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.07 Å Release Date: 2022-05-04 Classification: TRANSFERASE Ligands: B8I |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-05-04
Ligands: B8I
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Irak4 In Complex With Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.03 Å Release Date: 2022-05-04 Classification: TRANSFERASE Ligands: B6I |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-05-04
Ligands: B6I
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Irak4 In Complex With Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.11 Å Release Date: 2022-05-04 Classification: TRANSFERASE Ligands: B4U |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-05-04
Ligands: B4U
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Irak4 In Complex With Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.30 Å Release Date: 2022-05-04 Classification: TRANSFERASE Ligands: B7R |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-05-04
Ligands: B7R
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Irak4 In Complex With Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.44 Å Release Date: 2020-10-28 Classification: SIGNALING PROTEIN Ligands: NBK |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-10-28
Ligands: NBK
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Irak4 In Complex With Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.99 Å Release Date: 2020-10-28 Classification: SIGNALING PROTEIN Ligands: N9Z |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-10-28
Ligands: N9Z
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Irak4 In Complex With Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.38 Å Release Date: 2020-10-28 Classification: SIGNALING PROTEIN Ligands: NB5 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-10-28
Ligands: NB5
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Irak4 In Complex With Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.32 Å Release Date: 2020-10-28 Classification: SIGNALING PROTEIN Ligands: NBW |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-10-28
Ligands: NBW
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Irak4 In Complex With Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.52 Å Release Date: 2020-10-28 Classification: SIGNALING PROTEIN Ligands: ND2 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-10-28
Ligands: ND2
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Pi3Kg In Complex With Compound 7
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.84 Å Release Date: 2019-01-30 Classification: TRANSFERASE Ligands: DD8 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-01-30
Ligands: DD8
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Crystal Structure Of Human C-Kit Kinase Domain In Complex With Azd3229-Analogue (Compound 18)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.33 Å Release Date: 2018-09-19 Classification: SIGNALING PROTEIN Ligands: F82 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-09-19
Ligands: F82
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Crystal Structure Of Human C-Kit Kinase Domain In Complex With Azd3229-Analogue (Compound 23)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.31 Å Release Date: 2018-09-19 Classification: SIGNALING PROTEIN Ligands: F88 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-09-19
Ligands: F88
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Crystal Structure Of Human C-Kit Kinase Domain In Complex With Azd3229-Analogue (Compound 35)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.01 Å Release Date: 2018-09-19 Classification: SIGNALING PROTEIN Ligands: F8B |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-09-19
Ligands: F8B