Search Count: 75
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Crystal Structure Of Plasmodium Falciparum Dihydroorotate Dehydrogenase Bound With Inhibitor Dsm1010 (6-Cyclopropyl-2,4-Dimethyl-3-(4-(Trifluoromethyl)Benzyl)-2,6-Dihydro-7H-Pyrazolo[3,4-C]Pyridin-7-One)
Organism: Plasmodium falciparum 3d7
Method: X-RAY DIFFRACTION Resolution:3.00 Å Release Date: 2025-01-29 Classification: OXIDOREDUCTASE Ligands: A1A5P, FMN, OG6 |
Organism: Plasmodium falciparum 3d7
Method: X-RAY DIFFRACTION
Release Date: 2025-01-29
Ligands: A1A5P, FMN, OG6
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Crystal Structure Of Plasmodium Falciparum Dihydroorotate Dehydrogenase Bound With Inhibitor Dsm679 (Ethyl 1,4-Dimethyl-5-((6-(Trifluoromethyl)Pyridin-3-Yl)Methyl)-1H-Pyrazole-3-Carboxylate)
Organism: Plasmodium falciparum 3d7
Method: X-RAY DIFFRACTION Resolution:2.41 Å Release Date: 2025-01-01 Classification: OXIDOREDUCTASE/INHIBITOR Ligands: A1A51, FMN, OG6, CIT, LDA |
Organism: Plasmodium falciparum 3d7
Method: X-RAY DIFFRACTION
Release Date: 2025-01-01
Ligands: A1A51, FMN, OG6, CIT, LDA
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Crystal Structure Of Plasmodium Falciparum Dihydroorotate Dehydrogenase Bound With Inhibitor Dsm681 (N-Cyclopropyl-1,4-Dimethyl-5-((6-(Trifluoromethyl)Pyridin-3-Yl)Methyl)-1H-Pyrazole-3-Carboxamide)
Organism: Plasmodium falciparum 3d7
Method: X-RAY DIFFRACTION Resolution:2.10 Å Release Date: 2025-01-01 Classification: OXIDOREDUCTASE/INHIBITOR Ligands: A1A52, FMN, OG6, NA |
Organism: Plasmodium falciparum 3d7
Method: X-RAY DIFFRACTION
Release Date: 2025-01-01
Ligands: A1A52, FMN, OG6, NA
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Crystal Structure Of Plasmodium Falciparum Dihydroorotate Dehydrogenase Bound With Inhibitor Dsm959 (6-Cyclopropyl-2,4-Dimethyl-3-((6-(Trifluoromethyl)Pyridin-3-Yl)Methyl)-2,6-Dihydro-7H-Pyrazolo[3,4-C]Pyridin-7-One)
Organism: Plasmodium falciparum 3d7
Method: X-RAY DIFFRACTION Resolution:3.10 Å Release Date: 2025-01-01 Classification: OXIDOREDUCTASE/INHIBITOR Ligands: A1A53, FMN, OG6 |
Organism: Plasmodium falciparum 3d7
Method: X-RAY DIFFRACTION
Release Date: 2025-01-01
Ligands: A1A53, FMN, OG6
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Crystal Structure Of Plasmodium Falciparum Dihydroorotate Dehydrogenase Bound With Inhibitor Dsm1153 (4,6-Dicyclopropyl-3-(3-Fluoro-4-(Trifluoromethyl)Benzyl)-2-Methyl-2,6-Dihydro-7H-Pyrazolo[3,4-D]Pyridazin-7-One)
Organism: Plasmodium falciparum 3d7
Method: X-RAY DIFFRACTION Resolution:3.15 Å Release Date: 2025-01-01 Classification: OXIDOREDUCTASE Ligands: A1A5Q, FMN, OG6 |
Organism: Plasmodium falciparum 3d7
Method: X-RAY DIFFRACTION
Release Date: 2025-01-01
Ligands: A1A5Q, FMN, OG6
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Crystal Structure Of Plasmodium Falciparum Dihydroorotate Dehydrogenase Bound With Inhibitor Dsm1174 (3-((7-Azaspiro[3.5]Nonan-7-Yl)Methyl)-4-Cyclopropyl-6-Ethyl-2-Methyl-2,6-Dihydro-7H-Pyrazolo[3,4-C]Pyridin-7-One)
Organism: Plasmodium falciparum 3d7
Method: X-RAY DIFFRACTION Resolution:3.30 Å Release Date: 2025-01-01 Classification: OXIDOREDUCTASE Ligands: A1A59, FMN, OG6 |
Organism: Plasmodium falciparum 3d7
Method: X-RAY DIFFRACTION
Release Date: 2025-01-01
Ligands: A1A59, FMN, OG6
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Crystal Structure Of Plasmodium Falciparum Dihydroorotate Dehydrogenase Bound With Inhibitor Dsm1398 ((S)-3-(Amino(3-Chloro-4-(Trifluoromethyl)Phenyl)(Cyclopropyl)Methyl)-6-Cyclopropyl-2-Methyl-2,6-Dihydro-7H-Pyrazolo[3,4-D]Pyridazin-7-One)
Organism: Plasmodium falciparum 3d7
Method: X-RAY DIFFRACTION Resolution:2.90 Å Release Date: 2025-01-01 Classification: OXIDOREDUCTASE Ligands: A1A6D, FMN, OG6, ACY |
Organism: Plasmodium falciparum 3d7
Method: X-RAY DIFFRACTION
Release Date: 2025-01-01
Ligands: A1A6D, FMN, OG6, ACY
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Crystal Structure Of Plasmodium Falciparum Dihydroorotate Dehydrogenase Bound With Inhibitor Dsm1211 ((R)-3-(Amino(6-(Trifluoromethyl)Pyridin-3-Yl)Methyl)-4-Cyclopropyl-6-Ethyl-2-Methyl-2,6-Dihydro-7H-Pyrazolo[3,4-C]Pyridin-7-One)
Organism: Plasmodium falciparum 3d7
Method: X-RAY DIFFRACTION Resolution:3.10 Å Release Date: 2025-01-01 Classification: OXIDOREDUCTASE Ligands: A1A6E, FMN, OG6 |
Organism: Plasmodium falciparum 3d7
Method: X-RAY DIFFRACTION
Release Date: 2025-01-01
Ligands: A1A6E, FMN, OG6
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Human Cyclophilin A Bound To A Series Of Acylcic And Macrocyclic Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.80 Å Release Date: 2020-06-24 Classification: ISOMERASE/ISOMERASE INHIBITOR Ligands: ZXX |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-06-24
Ligands: ZXX
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Human Cyclophilin A Bound To A Series Of Acylcic And Macrocyclic Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.40 Å Release Date: 2020-06-24 Classification: ISOMERASE/ISOMERASE INHIBITOR Ligands: UMM |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-06-24
Ligands: UMM
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Human Cyclophilin A Bound To A Series Of Acylcic And Macrocyclic Inhibitors: Tert-Butyl [(2S)-1-{[(3S,17S)-2,16-Dioxo-10,15-Dioxa-1,21-Diazatricyclo[15.3.1.1~5,9~]Docosa-5(22),6,8-Trien-3-Yl]Amino}-3-Methyl-1-Oxobutan-2-Yl]Carbamate (Compound 3)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.50 Å Release Date: 2020-06-24 Classification: ISOMERASE/ISOMERASE INHIBITOR Ligands: UMM |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-06-24
Ligands: UMM
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Human Cyclophilin A Bound To A Series Of Acylcic And Macrocyclic Inhibitors: (2R,5S,11S,14S,18E)-2,11,17,17-Tetramethyl-14-(Propan-2-Yl)-3-Oxa-9,12,15,26,29-Pentaazatetracyclo[18.5.3.1~5,9~.0~23,27~]Nonacosa-1(25),18,20(28),21,23,26-Hexaene-4,10,13,16-Tetrone (Compound 24)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.51 Å Release Date: 2020-06-24 Classification: ISOMERASE/ISOMERASE INHIBITOR Ligands: UOD |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-06-24
Ligands: UOD
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Human Cyclophilin A Bound To A Series Of Acylcic And Macrocyclic Inhibitors: (2R,5S,11S,14S,18E)-2,11-Dimethyl-14-(Propan-2-Yl)-3-Oxa-9,12,15,21,29-Pentaazatetracyclo[18.5.3.1~5,9~.0~23,27~]Nonacosa-1(26),18,20,22,24,27-Hexaene-4,10,13,16-Tetrone (Compound 21)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.50 Å Release Date: 2020-06-24 Classification: ISOMERASE/ISOMERASE INHIBITOR Ligands: UO7 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-06-24
Ligands: UO7
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Human Cyclophilin A Bound To A Series Of Acylcic And Macrocyclic Inhibitors: (2R,5S,11S,14S,18E)-2,11,17,17-Tetramethyl-14-(Propan-2-Yl)-15-Oxa-3,9,12,26,29-Pentaazatetracyclo[18.5.3.1~5,9~.0~23,27~]Nonacosa-1(25),18,20(28),21,23,26-Hexaene-4,10,13,16-Tetrone (Compound 28)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.50 Å Release Date: 2020-06-24 Classification: ISOMERASE/ISOMERASE INHIBITOR Ligands: UOG |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-06-24
Ligands: UOG
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Human Cyclophilin A Bound To A Series Of Acylcic And Macrocyclic Inhibitors: (2R,5S,11S,14S,18E)-14-Cyclobutyl-2,11,17,17-Tetramethyl-15-Oxa-3,9,12,26,29-Pentaazatetracyclo[18.5.3.1~5,9~.0~23,27~]Nonacosa-1(25),18,20(28),21,23,26-Hexaene-4,10,13,16-Tetrone (Compound 33)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.80 Å Release Date: 2020-06-24 Classification: ISOMERASE/ISOMERASE INHIBITOR Ligands: UOJ |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-06-24
Ligands: UOJ
 |
Ctbp1 Bound To Inhibitor 2-(Hydroxyimino)-3-Phenylpropanoic Acid
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.30 Å Release Date: 2015-02-11 Classification: OXIDOREDUCTASE Ligands: NAI, 3CR, CA, FMT |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-02-11
Ligands: NAI, 3CR, CA, FMT
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Ctbp1 In Complex With Substrate Phenylpyruvate
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.10 Å Release Date: 2015-02-11 Classification: OXIDOREDUCTASE Ligands: NAD, PPY, CA, FMT |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-02-11
Ligands: NAD, PPY, CA, FMT
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Candida Albicans Dihydrofolate Reductase Complexed With Nadph And 5-[3-(2,5-Dimethoxy-4-Phenylphenyl)But-1-Yn-1-Yl]-6-Methylpyrimidine-2,4-Diamine (Ucp111E)
Organism: Candida albicans
Method: X-RAY DIFFRACTION Resolution:1.76 Å Release Date: 2014-03-19 Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR Ligands: NDP, 18G, GLY, GOL |
Organism: Candida albicans
Method: X-RAY DIFFRACTION
Release Date: 2014-03-19
Ligands: NDP, 18G, GLY, GOL
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Candida Albicans Dihydrofolate Reductase Complexed With Nadph And 5-[3-(2-Methoxy-4-Phenylphenyl)But-1-Yn-1-Yl]-6-Methylpyrimidine-2,4-Diamine (Ucp111H)
Organism: Candida albicans
Method: X-RAY DIFFRACTION Resolution:1.76 Å Release Date: 2014-03-19 Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR Ligands: NDP, 18H, GLY, GOL |
Organism: Candida albicans
Method: X-RAY DIFFRACTION
Release Date: 2014-03-19
Ligands: NDP, 18H, GLY, GOL
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Candida Glabrata Dihydrofolate Reductase Complexed With Nadph And 5-[3-(2-Methoxy-4-Phenylphenyl)But-1-Yn-1-Yl]-6-Methylpyrimidine-2,4-Diamine (Ucp111H)
Organism: Candida glabrata cbs 138
Method: X-RAY DIFFRACTION Resolution:2.00 Å Release Date: 2014-03-19 Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR Ligands: NDP, 18H, CL |
Organism: Candida glabrata cbs 138
Method: X-RAY DIFFRACTION
Release Date: 2014-03-19
Ligands: NDP, 18H, CL