Search Count: 49
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Pim-Inhibitor Complex 1
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.07 Å Release Date: 2020-11-04 Classification: ONCOPROTEIN,TRANSFERASE/INHIBITOR Ligands: IMD, ROY, ACT |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-11-04
Ligands: IMD, ROY, ACT
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Discovery Of Sarxxxx92, A Pan-Pim Kinase Inhibitor, Efficacious In A Kg1 Tumor Model
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.74 Å Release Date: 2020-11-04 Classification: ONCOPROTEIN,TRANSFERASE/INHIBITOR Ligands: WFY, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-11-04
Ligands: WFY, GOL
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Crystal Structure Of Bace1 In Complex With 2-Aminooxazoline 3-Aza-4-Fluoro-Xanthene Inhibitor 22
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.85 Å Release Date: 2015-03-04 Classification: Hydrolase/Hydrolase Inhibitor Ligands: IOD, GOL, 3UT |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-03-04
Ligands: IOD, GOL, 3UT
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Crystal Structure Of Bace1 In Complex With 2-Aminooxazoline 3-Azaxanthene Inhibitor 28
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.80 Å Release Date: 2015-02-04 Classification: Hydrolase/hydrolase inhibitor Ligands: IOD, 43K, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-02-04
Ligands: IOD, 43K, GOL
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Crystal Structure Of Bace1 In Complex With A 2-Aminooxazoline 4-Azaxanthene Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.90 Å Release Date: 2015-01-21 Classification: Hydrolase/Hydrolase inhibitor Ligands: 3LL, IOD, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-01-21
Ligands: 3LL, IOD, GOL
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Crystal Structure Of Bace1 In Complex With Aminooxazoline Xanthene Inhibitor 2
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.40 Å Release Date: 2014-12-24 Classification: Hydrolase/Hydrolase inhibitor Ligands: 3LN, IOD |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-12-24
Ligands: 3LN, IOD
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Crystal Structure Of Bace1 In Complex With 2-Aminooxazoline 4-Fluoroxanthene Inhibitor 49
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.78 Å Release Date: 2014-12-24 Classification: Hydrolase/Hydrolase inhibitor Ligands: IOD, 3LO, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-12-24
Ligands: IOD, 3LO, GOL
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Hydroxyethylamine-Based Inhibitors Of Bace1: P1-P3 Macrocyclization Can Improve Potency, Selectivity, And Cell Activity
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.39 Å Release Date: 2013-07-10 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: 1QT |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-07-10
Ligands: 1QT
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Bace-1 Inhibitor Complex
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.29 Å Release Date: 2013-07-10 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: 1QU |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-07-10
Ligands: 1QU
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Crystal Structure Of Bace1 In Complex With Hydroxyethylamine-Macrocyclic Inhibitor 13
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.30 Å Release Date: 2013-07-03 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: 1R8, GOL, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-07-03
Ligands: 1R8, GOL, SO4
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Crystal Structure Of Bace1 In Complex With Hydroxyethylamine-Macrocyclic Inhibitor 19
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.91 Å Release Date: 2013-07-03 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: IOD, 1R6, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-07-03
Ligands: IOD, 1R6, GOL
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Crystal Structure Of Ck1G3 With 2-[(4-{[3-(Trifluoromethyl)Pyridin2-Yl]Oxy}Phenyl)Amino]-1H-Benzimidazole-6-Carbonitrile
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.30 Å Release Date: 2013-05-22 Classification: TRANSFERASE/TRANSFERASE inhibitor Ligands: 0VM |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-05-22
Ligands: 0VM
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Crystal Structure Of Ck1G3 With 2-[(4-Tert-Butylphenyl)Amino]-1H-Benzimidazole-6-Carbonitrile
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.10 Å Release Date: 2013-05-22 Classification: TRANSFERASE/TRANSFERASE inhibitor Ligands: 0VN |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-05-22
Ligands: 0VN
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Crystal Structure Of Ck1G3 With Compound 1
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.40 Å Release Date: 2012-11-21 Classification: transferase/transferase inhibitor Ligands: 0YO, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2012-11-21
Ligands: 0YO, SO4
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Crystal Structure Of Ck1D With Compound 13
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.80 Å Release Date: 2012-11-21 Classification: transferase/transferase inhibitor Ligands: 15G |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2012-11-21
Ligands: 15G
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Crystal Structure Of Bace1 In Complex With Hydroxyethylamine Inhibitor 37
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.00 Å Release Date: 2012-10-10 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: 0K9, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2012-10-10
Ligands: 0K9, GOL
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Crystal Structure Of Bace1 In Complex With Biarylspiro Aminooxazoline 6
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.30 Å Release Date: 2012-09-12 Classification: HYDROLASE/INHIBITOR Ligands: IOD, DWA, DMS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2012-09-12
Ligands: IOD, DWA, DMS
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Crystal Structure Of Bace1 In Complex With Aminooxazoline Xanthene 9L
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.95 Å Release Date: 2012-09-12 Classification: HYDROLASE/INHIBITOR Ligands: IOD, DWB, GOL, DMS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2012-09-12
Ligands: IOD, DWB, GOL, DMS
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Crystal Structure Of Bace1 In Complex With Aminooxazoline Xanthene 11A
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.10 Å Release Date: 2012-09-12 Classification: HYDROLASE/INHIBITOR Ligands: IOD, DWD, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2012-09-12
Ligands: IOD, DWD, GOL
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Structure Of Bace-1 (Beta-Secretase) In Complex With (2R)-N-((2S,3R)-1-(Benzo[D][1,3]Dioxol-5-Yl)-3-Hydroxy-4-((S)-6'-Neopentyl-3',4'-Dihydrospiro[Cyclobutane-1,2'-Pyrano[2,3-B]Pyridine]-4'-Ylamino)Butan-2-Yl)-2-Methoxypropanamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.50 Å Release Date: 2012-04-18 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: IOD, GOL, 0KN |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2012-04-18
Ligands: IOD, GOL, 0KN