Search Count: 21
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Discovery Of A Small Molecule Itk And Pan-Trk Kinase Inhibitor (Pf-07245303) For The Potential Topical Treatment Of Atopic Dermatitis
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.35 Å Release Date: 2025-11-19 Classification: SIGNALING PROTEIN Ligands: A1B66 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-11-19
Ligands: A1B66
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Pad2 With An Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.18 Å Release Date: 2025-07-30 Classification: HYDROLASE Ligands: A1CE0, CA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-07-30
Ligands: A1CE0, CA
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Structure Of Hba With Compound (S)-4
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.23 Å Release Date: 2021-01-13 Classification: OXYGEN TRANSPORT Ligands: HEM, CMO, O4B, VOJ, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-01-13
Ligands: HEM, CMO, O4B, VOJ, GOL
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Structure Of Hba With Compound 9
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.63 Å Release Date: 2021-01-13 Classification: OXYGEN TRANSPORT Ligands: HEM, CMO, O4B, VOM |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-01-13
Ligands: HEM, CMO, O4B, VOM
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Structure Of Hba With Compound 19
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.59 Å Release Date: 2021-01-13 Classification: OXYGEN TRANSPORT Ligands: HEM, CMO, O4B, VOP |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-01-13
Ligands: HEM, CMO, O4B, VOP
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Structure Of Hba With Compound 23 (Pf-07059013)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.48 Å Release Date: 2021-01-13 Classification: OXYGEN TRANSPORT Ligands: HEM, OXY, O4B, VUD |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-01-13
Ligands: HEM, OXY, O4B, VUD
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Crystal Structure Of Mouse Btk Kinase Domain In Complex With Compound 9A
Organism: Mus musculus
Method: X-RAY DIFFRACTION Resolution:2.80 Å Release Date: 2019-01-30 Classification: TRANSFERASE Ligands: JVP |
Organism: Mus musculus
Method: X-RAY DIFFRACTION
Release Date: 2019-01-30
Ligands: JVP
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Crystal Structure Of Human Set And Mynd Domain Containing Protein 2 With Mtf9975
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.55 Å Release Date: 2018-03-14 Classification: TRANSFERASE/INHIBITOR Ligands: ZN, EW4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-03-14
Ligands: ZN, EW4
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Crystal Structure Of Jak1 In Complex With Compound 25
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.08 Å Release Date: 2018-01-17 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: D7D |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-01-17
Ligands: D7D
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Crystal Structure Of Jak2 In Complex With Compound 25
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.80 Å Release Date: 2018-01-17 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: D7D |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-01-17
Ligands: D7D
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Crystal Structure Of Itk In Complex With Compound 1 [4-(Carbamoylamino)-1-(Naphthalen-1-Yl)-1H-Pyrazole-3-Carboxamide]
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.70 Å Release Date: 2014-04-02 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: M0Y |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-04-02
Ligands: M0Y
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Crystal Structure Of Itk In Complex With Compound 5 {4-(Carbamoylamino)-1-(7-Methoxynaphthalen-1-Yl)-1H-Pyrazole-3-Carboxamide}
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.00 Å Release Date: 2014-04-02 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: M0Z |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-04-02
Ligands: M0Z
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Crystal Structure Of Itk In Complex With Compound 7 [4-(Carbamoylamino)-1-(7-Ethoxynaphthalen-1-Yl)-1H-Pyrazole-3-Carboxamide]
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.15 Å Release Date: 2014-04-02 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 1YZ |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-04-02
Ligands: 1YZ
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Crystal Structure Of Itk In Complex With Compound 8 [4-(Carbamoylamino)-1-(7-Propoxynaphthalen-1-Yl)-1H-Pyrazole-3-Carboxamide]
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.85 Å Release Date: 2014-04-02 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 1E0 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-04-02
Ligands: 1E0
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Crystal Structure Of Itk In Complex With Compound 9 [4-(Carbamoylamino)-1-[7-(Propan-2-Yloxy)Naphthalen-1-Yl]-1H-Pyrazole-3-Carboxamide]
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.55 Å Release Date: 2014-04-02 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: QWS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-04-02
Ligands: QWS
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Crystal Structure Of Itk In Complex With Compound 9 [4-(Carbamoylamino)-1-[7-(Propan-2-Yloxy)Naphthalen-1-Yl]-1H-Pyrazole-3-Carboxamide] And Adp
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.52 Å Release Date: 2014-04-02 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: QWS, ADP |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-04-02
Ligands: QWS, ADP
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Inhibitor Bound To A Dfg-Out Structure Of The Kinase Domain Of Csf-1R
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.40 Å Release Date: 2010-09-15 Classification: TRANSFERASE Ligands: LC0 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2010-09-15
Ligands: LC0
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Inhibitor Bound To A Dfg-In Structure Of The Kinase Domain Of Csf-1R
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.50 Å Release Date: 2010-03-02 Classification: TRANSFERASE Ligands: SO4, BDY |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2010-03-02
Ligands: SO4, BDY
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Crystal Structure Of An Optimzied Benzothiophene Inhibitor Bound To Mapkap Kinase-2 (Mk-2)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.80 Å Release Date: 2009-04-07 Classification: TRANSFERASE Ligands: B97 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2009-04-07
Ligands: B97
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Crystal Structure Of A Benzthiophene Lead Bound To Mapkap Kinase-2 (Mk-2)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.50 Å Release Date: 2009-04-07 Classification: TRANSFERASE Ligands: B98 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2009-04-07
Ligands: B98