Search Count: 13
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Crystal Structure Of The Noncovalently Bonded Complex Of Rilzabrutinib With Btk
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.21 Å Release Date: 2022-06-29 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: R1L, DMS, PEG, EDO, SO4, ACT |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-06-29
Ligands: R1L, DMS, PEG, EDO, SO4, ACT
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Crystal Structure Of The Covalently Bonded Complex Of Rilzabrutinib With Btk
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.14 Å Release Date: 2022-06-29 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: R1L, SO4, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-06-29
Ligands: R1L, SO4, EDO
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Bruton'S Tyrosine Kinase In Complex With A T-Butyl Cyanoacrylamide Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.20 Å Release Date: 2015-05-13 Classification: TRANSFERASE Ligands: 4C9, NA, EDO, SO4, CL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-05-13
Ligands: 4C9, NA, EDO, SO4, CL
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Crystal Structure Of Btk Kinase Domain Complexed With 6-(Dimethylamino)-2-[2-(Hydroxymethyl)-3-[1-Methyl-5-[[5-(Morpholine-4-Carbonyl)-2-Pyridyl]Amino]-6-Oxo-3-Pyridyl]Phenyl]-3,4-Dihydroisoquinolin-1-One
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.70 Å Release Date: 2014-12-24 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 3OU, DMS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-12-24
Ligands: 3OU, DMS
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Crystal Structure Of Btk Kinase Domain Complexed With 6-(Dimethylamino)-8-Fluoro-2-[2-(Hydroxymethyl)-3-[1-Methyl-5-[[5-(Morpholine-4-Carbonyl)-2-Pyridyl]Amino]-6-Oxo-3-Pyridyl]Phenyl]Isoquinolin-1-One
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.17 Å Release Date: 2014-12-24 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 3OV, DMS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-12-24
Ligands: 3OV, DMS
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Crystal Structure Of Btk Kinase Domain Complexed With 2-[8-Fluoro-2-[2-(Hydroxymethyl)-3-[1-Methyl-5-[[5-(4-Methylpiperazin-1-Yl)-2-Pyridyl]Amino]-6-Oxo-3-Pyridyl]Phenyl]-1-Oxo-3,4-Dihydroisoquinolin-6-Yl]-2-Methyl-Propanenitrile
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.50 Å Release Date: 2014-12-24 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 3P0 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-12-24
Ligands: 3P0
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Crystal Structure Of Btk Kinase Domain Complexed With 4-Tert-Butyl-N-(3-{8-[4-(4-Methyl-Piperazine-1-Carbonyl)-Phenylamino]-Imidazo[1,2-A]Pyrazin-6-Yl}-Phenyl)-Benzamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.55 Å Release Date: 2014-05-14 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 481, DMS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-05-14
Ligands: 481, DMS
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Crystal Structure Of Btk Kinase Domain Complexed With 4-Methanesulfonyl-N-(3-{8-[4-(Morpholine-4-Carbonyl)-Phenylamino]-Imidazo[1,2-A]Pyrazin-6-Yl}-Phenyl)-Benzamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.05 Å Release Date: 2014-05-14 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 2V1 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-05-14
Ligands: 2V1
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Crystal Structure Of Btk Kinase Domain Complexed With 1-[5-[3-(7-Tert-Butyl-4-Oxo-Quinazolin-3-Yl)-2-Methyl-Phenyl]-1-Methyl-2-Oxo-3-Pyridyl]-3-Methyl-Urea
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.55 Å Release Date: 2014-05-14 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 2V2, DMS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-05-14
Ligands: 2V2, DMS
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Crystal Structure Of Btk Kinase Domain Complexed With 6-Cyclopropyl-2-[3-[5-[[5-(4-Ethylpiperazin-1-Yl)-2-Pyridyl]Amino]-1-Methyl-6-Oxo-3-Pyridyl]-2-(Hydroxymethyl)Phenyl]-8-Fluoro-Isoquinolin-1-One
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.95 Å Release Date: 2014-05-14 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 2V3, DMS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-05-14
Ligands: 2V3, DMS
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Crystal Structure Of Spleen Tyrosine Kinase Complexed With 2-(3,4,5-Trimethoxy-Phenyl)-5H-Pyrrolo[2,3-B]Pyrazine-7-Carboxylic Acid Isopropylamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.10 Å Release Date: 2013-10-30 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 1B4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-10-30
Ligands: 1B4
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Crystal Structure Of Spleen Tyrosine Kinase Complexed With 2-(6-Chloro-1-Methyl-1H-Indazol-3-Yl)-5H-Pyrrolo[2,3-B]Pyrazine-7-Carboxylic Acid Isopropylamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.98 Å Release Date: 2013-10-30 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 1B5 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-10-30
Ligands: 1B5
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Crystal Structure Of Spleen Tyrosine Kinase Complexed With 2-(5,6,7,8-Tetrahydro-Imidazo[1,5-A]Pyridin-1-Yl)-5H-Pyrrolo[2,3-B]Pyrazine-7-Carboxylic Acid Tert-Butylamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.70 Å Release Date: 2013-10-30 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 1B6 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-10-30
Ligands: 1B6