Search Count: 38
 |
Diazabicyclooctenone Etx2514 Bound To Class D Beta Lactamase Oxa-24 From A. Baumannii
Organism: Acinetobacter baumannii
Method: X-RAY DIFFRACTION Resolution:1.93 Å Release Date: 2017-06-07 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: SO4, 9CP, 9CM |
Organism: Acinetobacter baumannii
Method: X-RAY DIFFRACTION
Release Date: 2017-06-07
Ligands: SO4, 9CP, 9CM
 |
Tmk From S.Aureus In Complex With The Piperidinyl Thymine Class Inhibitor With A C5 Ethyl-Amine
Organism: Staphylococcus aureus (strain mu3 / atcc 700698)
Method: X-RAY DIFFRACTION Resolution:1.89 Å Release Date: 2015-02-11 Classification: TRANSFERASE Ligands: 43N |
Organism: Staphylococcus aureus (strain mu3 / atcc 700698)
Method: X-RAY DIFFRACTION
Release Date: 2015-02-11
Ligands: 43N
 |
Crystal Structure Of The E. Coli Ribosome Bound To Negamycin.
Organism: Escherichia coli str. k-12 substr. mg1655, Escherichia coli, Thermus thermophilus
Method: X-RAY DIFFRACTION Resolution:3.09 Å Release Date: 2014-11-05 Classification: Ribosome/Antibiotic Ligands: MG, ZN, NEG |
Organism: Escherichia coli str. k-12 substr. mg1655, Escherichia coli, Thermus thermophilus
Method: X-RAY DIFFRACTION
Release Date: 2014-11-05
Ligands: MG, ZN, NEG
 |
Lpxc From P.Aeruginosa With The Inhibitor 6-(Benzimidazol-1-Yl)-5-[4-[2-[6-[(4-Methylpiperazin-1-Yl)Methyl]-3-Pyridyl]Ethynyl]Phenyl]Pyridine-3-Carbohydroxamic Acid
Organism: Pseudomonas aeruginosa
Method: X-RAY DIFFRACTION Resolution:2.06 Å Release Date: 2014-09-24 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: ZN, 2SZ |
Organism: Pseudomonas aeruginosa
Method: X-RAY DIFFRACTION
Release Date: 2014-09-24
Ligands: ZN, 2SZ
 |
Avibactam And Class C Beta-Lactamases: Mechanism Of Inhibition, Conservation Of Binding Pocket And Implications For Resistance
Organism: Pseudomonas aeruginosa
Method: X-RAY DIFFRACTION Resolution:1.10 Å Release Date: 2014-08-20 Classification: hydrolase/hydrolase inhibitor Ligands: NXL |
Organism: Pseudomonas aeruginosa
Method: X-RAY DIFFRACTION
Release Date: 2014-08-20
Ligands: NXL
 |
A.Aolicus Lpxc In Complex With Native Product
Organism: Aquifex aeolicus
Method: X-RAY DIFFRACTION Resolution:1.61 Å Release Date: 2014-08-13 Classification: HYDROLASE Ligands: ZN, CL, 24G |
Organism: Aquifex aeolicus
Method: X-RAY DIFFRACTION
Release Date: 2014-08-13
Ligands: ZN, CL, 24G
 |
Crystal Structure Of The E. Coli Ribosome Bound To Quinupristin.
Organism: Synthetic construct, Escherichia coli str. k-12 substr. mds42, Escherichia coli, Thermus thermophilus
Method: X-RAY DIFFRACTION Resolution:2.95 Å Release Date: 2014-07-30 Classification: RIBOSOME Ligands: MG, ZN |
Organism: Synthetic construct, Escherichia coli str. k-12 substr. mds42, Escherichia coli, Thermus thermophilus
Method: X-RAY DIFFRACTION
Release Date: 2014-07-30
Ligands: MG, ZN
 |
Crystal Structure Of The E. Coli Ribosome Bound To Linopristin.
Organism: Synthetic construct, Escherichia coli str. k-12 substr. mds42, Escherichia coli, Thermus thermophilus
Method: X-RAY DIFFRACTION Resolution:3.00 Å Release Date: 2014-07-30 Classification: RIBOSOME Ligands: MG, ZN |
Organism: Synthetic construct, Escherichia coli str. k-12 substr. mds42, Escherichia coli, Thermus thermophilus
Method: X-RAY DIFFRACTION
Release Date: 2014-07-30
Ligands: MG, ZN
 |
Crystal Structure Of The E. Coli Ribosome Bound To Flopristin.
Organism: Escherichia coli str. k-12 substr. mds42, Escherichia coli, Thermus thermophilus
Method: X-RAY DIFFRACTION Resolution:2.90 Å Release Date: 2014-07-30 Classification: RIBOSOME Ligands: MG, VIF, ZN |
Organism: Escherichia coli str. k-12 substr. mds42, Escherichia coli, Thermus thermophilus
Method: X-RAY DIFFRACTION
Release Date: 2014-07-30
Ligands: MG, VIF, ZN
 |
Crystal Structure Of The E. Coli Ribosome Bound To Dalfopristin.
Organism: Escherichia coli str. k-12 substr. mds42, Escherichia coli, Thermus thermophilus
Method: X-RAY DIFFRACTION Resolution:2.90 Å Release Date: 2014-07-30 Classification: RIBOSOME Ligands: MG, DOL, ZN |
Organism: Escherichia coli str. k-12 substr. mds42, Escherichia coli, Thermus thermophilus
Method: X-RAY DIFFRACTION
Release Date: 2014-07-30
Ligands: MG, DOL, ZN
 |
Crystal Structure Of The E. Coli Ribosome Bound To Virginiamycin M1.
Organism: Escherichia coli str. k-12 substr. mds42, Escherichia coli, Thermus thermophilus
Method: X-RAY DIFFRACTION Resolution:2.90 Å Release Date: 2014-07-30 Classification: RIBOSOME Ligands: MG, VIR, ZN |
Organism: Escherichia coli str. k-12 substr. mds42, Escherichia coli, Thermus thermophilus
Method: X-RAY DIFFRACTION
Release Date: 2014-07-30
Ligands: MG, VIR, ZN
 |
Crystal Structure Of The E. Coli Ribosome Bound To Dalfopristin And Quinupristin.
Organism: Synthetic construct, Escherichia coli str. k-12 substr. mds42, Escherichia coli, Thermus thermophilus
Method: X-RAY DIFFRACTION Resolution:2.80 Å Release Date: 2014-07-30 Classification: RIBOSOME Ligands: MG, DOL, ZN |
Organism: Synthetic construct, Escherichia coli str. k-12 substr. mds42, Escherichia coli, Thermus thermophilus
Method: X-RAY DIFFRACTION
Release Date: 2014-07-30
Ligands: MG, DOL, ZN
 |
Crystal Structure Of The E. Coli Ribosome Bound To Flopristin And Linopristin.
Organism: Synthetic construct, Escherichia coli str. k-12 substr. mds42, Escherichia coli, Thermus thermophilus
Method: X-RAY DIFFRACTION Resolution:2.80 Å Release Date: 2014-07-30 Classification: RIBOSOME Ligands: MG, VIF, ZN |
Organism: Synthetic construct, Escherichia coli str. k-12 substr. mds42, Escherichia coli, Thermus thermophilus
Method: X-RAY DIFFRACTION
Release Date: 2014-07-30
Ligands: MG, VIF, ZN
 |
S.Aureus Tmk In Complex With A Potent Inhibitor Compound 18, 2-(3-Chlorophenoxy)-3-Methoxy-4-{[(3S)-3-(5-Methyl-2,4-Dioxo-3,4-Dihydropyrimidin-1(2H)-Yl)Piperidin-1-Yl]Methyl}Benzoic Acid
Organism: Staphylococcus aureus subsp. aureus
Method: X-RAY DIFFRACTION Resolution:1.67 Å Release Date: 2014-06-11 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 32K |
Organism: Staphylococcus aureus subsp. aureus
Method: X-RAY DIFFRACTION
Release Date: 2014-06-11
Ligands: 32K
 |
S.Aureus Tmk In Complex With Potent Inhibitor Compound 19, 2-(3-Chlorophenoxy)-3-Fluoro-4-{[(3S)-3-(5-Methyl-2,4-Dioxo-3,4-Dihydropyrimidin-1(2H)-Yl)Piperidin-1-Yl]Methyl}Benzoic Acid
Organism: Staphylococcus aureus subsp. aureus
Method: X-RAY DIFFRACTION Resolution:1.94 Å Release Date: 2014-06-11 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 31Z |
Organism: Staphylococcus aureus subsp. aureus
Method: X-RAY DIFFRACTION
Release Date: 2014-06-11
Ligands: 31Z
 |
S.Aureus Tmk In Complex With The Potent Inhibitor Compound 38, 2-(3-Chlorophenoxy)-3-Methoxy-4-{(1R)-1-[(3S)-3-(5-Methyl-2,4-Dioxo-3,4-Dihydropyrimidin-1(2H)-Yl)Piperidin-1-Yl]Propyl}Benzoic Acid
Organism: Staphylococcus aureus subsp. aureus
Method: X-RAY DIFFRACTION Resolution:1.83 Å Release Date: 2014-06-11 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 32B |
Organism: Staphylococcus aureus subsp. aureus
Method: X-RAY DIFFRACTION
Release Date: 2014-06-11
Ligands: 32B
 |
Tmk In Complex With Compound 46, 2-(3-Chlorophenoxy)-3-Fluoro-4-{(1R)-3-Methyl-1-[(3S)-3-(5-Methyl-2,4-Dioxo-3,4-Dihydropyrimidin-1(2H)-Yl)Piperidin-1-Yl]Butyl}Benzoic Acid
Organism: Staphylococcus aureus subsp. aureus
Method: X-RAY DIFFRACTION Resolution:1.62 Å Release Date: 2014-06-11 Classification: Transferase/transferase inhibitor Ligands: 32C |
Organism: Staphylococcus aureus subsp. aureus
Method: X-RAY DIFFRACTION
Release Date: 2014-06-11
Ligands: 32C
 |
S.Aureus Tmk In Complex With Potent Inhibitor Compound 47
Organism: Staphylococcus aureus subsp. aureus
Method: X-RAY DIFFRACTION Resolution:1.78 Å Release Date: 2014-06-11 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 32E |
Organism: Staphylococcus aureus subsp. aureus
Method: X-RAY DIFFRACTION
Release Date: 2014-06-11
Ligands: 32E
 |
Sulfonylpiperidines As Novel, Antibacterial Inhibitors Of Gram-Positive Thymidylate Kinase (Tmk): Compound 5
Organism: Staphylococcus aureus subsp. aureus
Method: X-RAY DIFFRACTION Resolution:1.55 Å Release Date: 2012-10-31 Classification: transferase/transferase inhibitor Ligands: T05 |
Organism: Staphylococcus aureus subsp. aureus
Method: X-RAY DIFFRACTION
Release Date: 2012-10-31
Ligands: T05
 |
Sulfonylpiperidines As Novel, Antibacterial Inhibitors Of Gram-Positive Thymidylate Kinase (Tmk): Compound 11
Organism: Staphylococcus aureus subsp. aureus
Method: X-RAY DIFFRACTION Resolution:2.00 Å Release Date: 2012-10-31 Classification: transferase/transferase inhibitor Ligands: 16T |
Organism: Staphylococcus aureus subsp. aureus
Method: X-RAY DIFFRACTION
Release Date: 2012-10-31
Ligands: 16T