Search Count: 20
 |
Crystal Structure Of P53 Y220C Mutant In Complex With Pc-10709
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.90 Å Release Date: 2025-03-26 Classification: TRANSFERASE Ligands: A1ARO, ZN |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-03-26
Ligands: A1ARO, ZN
 |
Crystal Structure Of Compound 16 Bound To Mdm2(17-111), {(3R,5R,6S)-5-(3-Chlorophenyl)-6-(4-Chlorophenyl)-1-[(1S)-1-Cyclopropyl-2-(Pyrrolidin-1-Ylsulfonyl)Ethyl]-3-Methyl-2-Oxopiperidin-3-Yl}Acetic Acid
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.70 Å Release Date: 2015-05-06 Classification: Ligase/Ligase inhibitor Ligands: 35T |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-05-06
Ligands: 35T
 |
Co-Crystal Structure Of Mdm2 In Complex With Am-7209
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.42 Å Release Date: 2014-12-03 Classification: LIGASE/LIGASE INHIBITOR Ligands: 3UD, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-12-03
Ligands: 3UD, SO4
 |
Co-Crystal Structure Of Mdm2 (17-111) With Compound 16, {(3R,5R,6S)-5-(3-Chlorophenyl)-6-(4-Chlorophenyl)-1-[(1S)-1-(6-Cyclopropylpyridin-2-Yl)Propyl]-3-Methyl-2-Oxopiperidin-3-Yl}Acetic Acid
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.70 Å Release Date: 2014-07-16 Classification: Ligase/Ligase inhibitor Ligands: 35S |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-07-16
Ligands: 35S
 |
Co-Crystal Structure Of Mdm2(17-111) In Complex With Compound 48
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.80 Å Release Date: 2014-04-02 Classification: ligase/ligase inhibitor Ligands: 2TZ |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-04-02
Ligands: 2TZ
 |
Co-Crystal Structure Of Mdm2 With Inhibitor Compound 4
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.80 Å Release Date: 2014-04-02 Classification: LIGASE/LIGASE INHIBITOR Ligands: 2U0, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-04-02
Ligands: 2U0, SO4
 |
Co-Crystal Structure Of Mdm2 With Inhibitor Compound 47
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.20 Å Release Date: 2014-04-02 Classification: LIGASE/LIGASE INHIBITOR Ligands: 2U1 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-04-02
Ligands: 2U1
 |
Co-Crystal Structure Of Mdm2 With Inhbitor Compound 3
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.38 Å Release Date: 2014-04-02 Classification: LIGASE/LIGASE INHIBITOR Ligands: 2U5, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-04-02
Ligands: 2U5, SO4
 |
Co-Crystal Structure Of Mdm2 With Inhbitor Compound 46
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.54 Å Release Date: 2014-04-02 Classification: LIGASE/LIGASE INHIBITOR Ligands: 2U6, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-04-02
Ligands: 2U6, SO4
 |
Co-Crystal Structure Of Mdm2 With Inhibitor Compound 49
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.20 Å Release Date: 2014-04-02 Classification: LIGASE/LIGASE INHIBITOR Ligands: 2U7 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-04-02
Ligands: 2U7
 |
Co-Crystal Structure Of Mdm2 With Inhibitor Compound 4
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.60 Å Release Date: 2014-03-19 Classification: ligase/ligase inhibitor Ligands: 2TW |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-03-19
Ligands: 2TW
 |
Co-Crystal Structure Of Mdm2 (17-111) In Complex With Compound 25
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.70 Å Release Date: 2014-02-19 Classification: ligase/ligase inhibitor Ligands: 2SW, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-02-19
Ligands: 2SW, SO4
 |
Co-Crystal Structure Of Mdm2 With Inhibitor (2S,5R,6S)-2-Benzyl-5,6-Bis(4-Bromophenyl)-4-Methylmorpholin-3-One
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.20 Å Release Date: 2013-05-01 Classification: LIGASE/LIGASE INHIBITOR Ligands: 1MN, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-05-01
Ligands: 1MN, SO4
 |
Co-Crystal Structure Of Mdm2 With Inhibitor (2S,5R,6S)-2-Benzyl-5,6-Bis(4-Chlorophenyl)-4-Methylmorpholin-3-One
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.50 Å Release Date: 2013-05-01 Classification: LIGASE/LIGASE INHIBITOR Ligands: 1MO, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-05-01
Ligands: 1MO, SO4
 |
Co-Crystal Structure Of Mdm2 With Inhibitor (2R,3E)-2-[(2S,3R,6S)-2,3-Bis(4-Chlorophenyl)-6-(4-Fluorobenzyl)-5-Oxomorpholin-4-Yl]Pent-3-Enoic Acid
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.30 Å Release Date: 2013-05-01 Classification: LIGASE/LIGASE INHIBITOR Ligands: 1MQ |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-05-01
Ligands: 1MQ
 |
Co-Crystal Structure Of Mdm2 With Inhibitor (2'S,3R,4'S,5'R)-N-(2-Aminoethyl)-6-Chloro-4'-(3-Chloro-2-Fluorophenyl)-2'-(2,2-Dimethylpropyl)-2-Oxo-1,2-Dihydrospiro[Indole-3,3'-Pyrrolidine]-5'-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.70 Å Release Date: 2013-05-01 Classification: LIGASE/LIGASE INHIBITOR Ligands: 1MT |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-05-01
Ligands: 1MT
 |
Co-Crystal Structure Of Mdm2 With Inhibitor {(2S,5R,6S)-6-(3-Chlorophenyl)-5-(4-Chlorophenyl)-4-[(2S)-1-Hydroxybutan-2-Yl]-3-Oxomorpholin-2-Yl}Acetic Acid
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.35 Å Release Date: 2013-05-01 Classification: LIGASE/LIGASE INHIBITOR Ligands: 1MY |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-05-01
Ligands: 1MY
 |
Crystal Structure Of Mdm2 (17-111) In Complex With Compound 23
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.80 Å Release Date: 2012-05-23 Classification: Ligase/Ligase inhibitor Ligands: 0R2, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2012-05-23
Ligands: 0R2, SO4
 |
Crystal Structure Of Mdm2 (17-111) In Complex With Compound 29 (Am-8553)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.00 Å Release Date: 2012-05-23 Classification: Ligase/Ligase inhibitor Ligands: 0R3 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2012-05-23
Ligands: 0R3
 |
Crystal Structure Of Mdm2 With Chromenotriazolopyrimidine 1
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.10 Å Release Date: 2009-11-17 Classification: LIGASE Ligands: YIN |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2009-11-17
Ligands: YIN