Search Count: 41
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Pyrazole Carboxylic Acid Inhibitors Of Keap1:Nrf2 Interaction
Organism: Mus musculus
Method: X-RAY DIFFRACTION Resolution:1.89 Å Release Date: 2021-11-17 Classification: PROTEIN BINDING Ligands: DMS, CL, 5UI |
Organism: Mus musculus
Method: X-RAY DIFFRACTION
Release Date: 2021-11-17
Ligands: DMS, CL, 5UI
 |
Pyrazole Carboxylic Acid Inhibitors Of Keap1:Nrf2 Interaction
Organism: Mus musculus
Method: X-RAY DIFFRACTION Resolution:1.87 Å Release Date: 2021-11-17 Classification: PROTEIN BINDING Ligands: DMS, CL, 5VX |
Organism: Mus musculus
Method: X-RAY DIFFRACTION
Release Date: 2021-11-17
Ligands: DMS, CL, 5VX
 |
Pyrazole Carboxylic Acid Inhibitors Of Keap1:Nrf2 Interaction
Organism: Mus musculus
Method: X-RAY DIFFRACTION Resolution:1.88 Å Release Date: 2021-11-17 Classification: PROTEIN BINDING Ligands: CL, 5QZ |
Organism: Mus musculus
Method: X-RAY DIFFRACTION
Release Date: 2021-11-17
Ligands: CL, 5QZ
 |
Pyrazole Carboxylic Acid Inhibitors Of Keap1:Nrf2 Interaction
Organism: Mus musculus
Method: X-RAY DIFFRACTION Resolution:1.86 Å Release Date: 2021-11-17 Classification: PROTEIN BINDING Ligands: CL, SO4, 5X9 |
Organism: Mus musculus
Method: X-RAY DIFFRACTION
Release Date: 2021-11-17
Ligands: CL, SO4, 5X9
 |
Pyrazole Carboxylic Acid Inhibitors Of Keap1:Nrf2 Interaction
Organism: Mus musculus
Method: X-RAY DIFFRACTION Resolution:1.79 Å Release Date: 2021-11-17 Classification: PROTEIN BINDING Ligands: CL, 5UZ |
Organism: Mus musculus
Method: X-RAY DIFFRACTION
Release Date: 2021-11-17
Ligands: CL, 5UZ
 |
Pyrazole Carboxylic Acid Inhibitors Of Keap1:Nrf2 Interaction
Organism: Mus musculus
Method: X-RAY DIFFRACTION Resolution:1.89 Å Release Date: 2021-11-17 Classification: PROTEIN BINDING Ligands: CL, 5RQ |
Organism: Mus musculus
Method: X-RAY DIFFRACTION
Release Date: 2021-11-17
Ligands: CL, 5RQ
 |
Pyrazole Carboxylic Acid Inhibitors Of Keap1:Nrf2 Interaction
Organism: Mus musculus
Method: X-RAY DIFFRACTION Resolution:1.85 Å Release Date: 2021-11-17 Classification: PROTEIN BINDING Ligands: CL, SO4, 5RB |
Organism: Mus musculus
Method: X-RAY DIFFRACTION
Release Date: 2021-11-17
Ligands: CL, SO4, 5RB
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The Structure Of Erk2 In Complex With Dual Inhibitor Astx029
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.76 Å Release Date: 2021-10-06 Classification: SIGNALING PROTEIN Ligands: SO4, DMS, RYW |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-10-06
Ligands: SO4, DMS, RYW
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Discovery Of Astx029, A Clinical Candidate Which Modulates The Phosphorylation And Catalytic Activity Of Erk1/2
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.94 Å Release Date: 2021-10-06 Classification: SIGNALING PROTEIN Ligands: SO4, DMS, UMN |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-10-06
Ligands: SO4, DMS, UMN
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Discovery Of Astx029, A Clinical Candidate Which Modulates The Phosphorylation And Catalytic Activity Of Erk1/2
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.78 Å Release Date: 2021-10-06 Classification: SIGNALING PROTEIN Ligands: SO4, DMS, UNW |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-10-06
Ligands: SO4, DMS, UNW
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Discovery Of Astx029, A Clinical Candidate Which Modulates The Phosphorylation And Catalytic Activity Of Erk1/2
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.90 Å Release Date: 2021-10-06 Classification: SIGNALING PROTEIN Ligands: SO4, UO5 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-10-06
Ligands: SO4, UO5
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Discovery Of Astx029, A Clinical Candidate Which Modulates The Phosphorylation And Catalytic Activity Of Erk1/2
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.77 Å Release Date: 2021-10-06 Classification: SIGNALING PROTEIN Ligands: SO4, UOH |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-10-06
Ligands: SO4, UOH
 |
Discovery Of Astx029, A Clinical Candidate Which Modulates The Phosphorylation And Catalytic Activity Of Erk1/2
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.63 Å Release Date: 2021-10-06 Classification: SIGNALING PROTEIN Ligands: SO4, DMS, EDO, UOE |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-10-06
Ligands: SO4, DMS, EDO, UOE
 |
Discovery Of Astx029, A Clinical Candidate Which Modulates The Phosphorylation And Catalytic Activity Of Erk1/2
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.91 Å Release Date: 2021-10-06 Classification: SIGNALING PROTEIN Ligands: SO4, UOW |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-10-06
Ligands: SO4, UOW
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Small Molecule Inhibitor Of The Keap1-Nrf2 Protein-Protein Interaction
Organism: Mus musculus
Method: X-RAY DIFFRACTION Resolution:1.77 Å Release Date: 2019-04-24 Classification: PROTEIN BINDING Ligands: J6H |
Organism: Mus musculus
Method: X-RAY DIFFRACTION
Release Date: 2019-04-24
Ligands: J6H
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Small Molecule Inhibitor Of The Keap1-Nrf2 Protein-Protein Interaction
Organism: Mus musculus
Method: X-RAY DIFFRACTION Resolution:1.94 Å Release Date: 2019-04-24 Classification: PROTEIN BINDING Ligands: DMS, J6N |
Organism: Mus musculus
Method: X-RAY DIFFRACTION
Release Date: 2019-04-24
Ligands: DMS, J6N
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Small Molecule Inhibitor Of The Keap1-Nrf2 Protein-Protein Interaction
Organism: Mus musculus
Method: X-RAY DIFFRACTION Resolution:1.81 Å Release Date: 2019-04-24 Classification: PROTEIN BINDING Ligands: SO4, J6Q |
Organism: Mus musculus
Method: X-RAY DIFFRACTION
Release Date: 2019-04-24
Ligands: SO4, J6Q
 |
Small Molecule Inhibitor Of The Keap1-Nrf2 Protein-Protein Interaction
Organism: Mus musculus
Method: X-RAY DIFFRACTION Resolution:1.86 Å Release Date: 2019-04-24 Classification: PROTEIN BINDING Ligands: SO4, CL, J6K |
Organism: Mus musculus
Method: X-RAY DIFFRACTION
Release Date: 2019-04-24
Ligands: SO4, CL, J6K
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Small Molecule Inhibitor Of The Keap1-Nrf2 Protein-Protein Interaction
Organism: Mus musculus
Method: X-RAY DIFFRACTION Resolution:1.72 Å Release Date: 2019-04-24 Classification: PROTEIN BINDING Ligands: CL, J8H |
Organism: Mus musculus
Method: X-RAY DIFFRACTION
Release Date: 2019-04-24
Ligands: CL, J8H
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Fragment-Based Discovery Of A Highly Potent, Orally Bioavailable Inhibitor Which Modulates The Phosphorylation And Catalytic Activity Of Erk1/2
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.76 Å Release Date: 2018-05-30 Classification: SIGNALING PROTEIN Ligands: SO4, EQT |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-05-30
Ligands: SO4, EQT