Search Count: 52
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Fibroblast Growth Factor Receptor 1 In Complex With Jnj-4275693
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.63 Å Release Date: 2016-03-30 Classification: TRANSFERASE Ligands: SO4, 5SF |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-03-30
Ligands: SO4, 5SF
 |
Disease Linked Mutation In Fgfr
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.58 Å Release Date: 2016-03-30 Classification: TRANSFERASE Ligands: SO4, ACT, CL, PGE |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-03-30
Ligands: SO4, ACT, CL, PGE
 |
Selective Estrogen Receptor Downregulator Antagonists: Tetrahydroisoquinoline Phenols 1.
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.88 Å Release Date: 2016-02-10 Classification: SIGNALING PROTEIN Ligands: GQD |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-02-10
Ligands: GQD
 |
Selective Estrogen Receptor Downregulator Antagonists: Tetrahydroisoquinoline Phenols 2.
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.88 Å Release Date: 2016-02-10 Classification: SIGNALING PROTEIN Ligands: QHG |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-02-10
Ligands: QHG
 |
Selective Estrogen Receptor Downregulator Antagonists: Tetrahydroisoquinoline Phenols 3.
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.94 Å Release Date: 2016-02-10 Classification: SIGNALING PROTEIN Ligands: J0W |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-02-10
Ligands: J0W
 |
Selective Estrogen Receptor Downregulator Antagonists: Tetrahydroisoquinoline Phenols 4.
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.99 Å Release Date: 2016-02-10 Classification: SIGNALING PROTEIN Ligands: 7QN |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-02-10
Ligands: 7QN
 |
Selective Estrogen Receptor Downregulator Antagonists: Tetrahydroisoquinoline Phenols 5.
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.74 Å Release Date: 2016-02-10 Classification: SIGNALING PROTEIN Ligands: VQI |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-02-10
Ligands: VQI
 |
A Novel Oral Selective Estrogen Receptor Down-Regulator, Azd9496, Drives Tumour Growth Inhibition In Estrogen Receptor Positive And Esr1 Mutant Models
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.88 Å Release Date: 2015-12-16 Classification: SIGNALING PROTEIN Ligands: KE9 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-12-16
Ligands: KE9
 |
Optimization Of A Novel Binding Motif To To (E)-3-(3,5-Difluoro-4-((1R,3R)-2-(2-Fluoro-2-Methylpropyl)-3-Methyl-2,3,4,9-Tetrahydro-1H- Pyrido(3,4-B)Indol-1-Yl)Phenyl)Acrylic Acid (Azd9496), A Potent And Orally Bioavailable Selective Estrogen Receptor Downregulator And Antagonist
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.90 Å Release Date: 2015-10-14 Classification: SIGNALING PROTEIN Ligands: XBR |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-10-14
Ligands: XBR
 |
Optimization Of A Novel Binding Motif To To (E)-3-(3,5-Difluoro-4-((1R,3R)-2-(2-Fluoro-2-Methylpropyl)-3-Methyl-2,3,4,9-Tetrahydro-1H- Pyrido(3,4-B)Indol-1-Yl)Phenyl)Acrylic Acid (Azd9496), A Potent And Orally Bioavailable Selective Estrogen Receptor Downregulator And Antagonist
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.95 Å Release Date: 2015-10-14 Classification: SIGNALING PROTEIN Ligands: GW5 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-10-14
Ligands: GW5
 |
Fibroblast Growth Factor Receptor 1 Kinase In Complex With Jk-P5
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.31 Å Release Date: 2015-09-02 Classification: TRANSFERASE Ligands: EDO, JVT, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-09-02
Ligands: EDO, JVT, SO4
 |
Fibroblast Growth Factor Receptor 1 Kinase In Complex With Jk-P3
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.96 Å Release Date: 2015-09-02 Classification: TRANSFERASE Ligands: EDO, 4Y0, PPI, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-09-02
Ligands: EDO, 4Y0, PPI, SO4
 |
Fgfr1 In Complex With Dovitinib
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.63 Å Release Date: 2015-08-05 Classification: TRANSFERASE Ligands: EDO, 38O, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-08-05
Ligands: EDO, 38O, SO4
 |
Fgfr1 Ligand Complex
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.09 Å Release Date: 2015-08-05 Classification: TRANSFERASE Ligands: SO4, EDO, XOJ |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-08-05
Ligands: SO4, EDO, XOJ
 |
Oxyphenylpropenoic Acids As Oral Selective Estrogen Receptor Down- Regulators.
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.19 Å Release Date: 2015-04-22 Classification: SIGNALING PROTEIN Ligands: 85Z |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-04-22
Ligands: 85Z
 |
Fgfr1 In Complex With Ponatinib (Co-Crystallisation).
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.33 Å Release Date: 2014-12-10 Classification: TRANSFERASE Ligands: SO4, EDO, 0LI |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-12-10
Ligands: SO4, EDO, 0LI
 |
Fgfr1 In Complex With Ponatinib.
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.12 Å Release Date: 2014-12-10 Classification: TRANSFERASE Ligands: EDO, 0LI, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-12-10
Ligands: EDO, 0LI, SO4
 |
Fgfr1 In Complex With Azd4547.
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.57 Å Release Date: 2014-12-10 Classification: TRANSFERASE Ligands: EDO, 66T, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-12-10
Ligands: EDO, 66T, SO4
 |
Fgfr4 In Complex With Ponatinib
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.85 Å Release Date: 2014-12-03 Classification: TRANSFERASE Ligands: SO4, 0LI |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-12-03
Ligands: SO4, 0LI
 |
Crystal Structure Of Human Fibroblast Growth Factor Receptor 1 Kinase Domain In Complex With Pyrazolaminopyrimidine 1
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.57 Å Release Date: 2013-12-18 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: EDO, SO4, 2K5 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-12-18
Ligands: EDO, SO4, 2K5