Search Count: 29
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Crystal Structure Of Human Pim-1 Kinase In Complex With A Quinazolinone-Pyrrolodihydropyrrolone Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.20 Å Release Date: 2019-01-16 Classification: TRANSFERASE Ligands: JYG, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-01-16
Ligands: JYG, GOL
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Crystal Structure Of Human Pim-1 Kinase In Complex With A Quinazolinone-Pyrrolopyrrolone Inhibitor.
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.10 Å Release Date: 2016-06-22 Classification: transferase/transferase inhibitor Ligands: 6CD, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-06-22
Ligands: 6CD, GOL
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B-Raf Wild-Type Kinase Domain In Complex With A Purinylpyridinylamino-Based Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.89 Å Release Date: 2016-05-04 Classification: Transferase/Transferase Inhibitor Ligands: 5XJ |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-05-04
Ligands: 5XJ
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Co-Crystal Structure Of Perk Bound To N-{5-[(6,7-Dimethoxyquinolin-4-Yl)Oxy]Pyridin-2-Yl}-1-Methyl-3-Oxo-2-Phenyl-5-(Pyridin-4-Yl)-2,3-Dihydro-1H-Pyrazole-4-Carboxamide Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.00 Å Release Date: 2015-02-04 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 3Z2, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-02-04
Ligands: 3Z2, SO4
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Co-Crystal Structure Of Perk With 2-Amino-N-[4-Methoxy-3-(Trifluoromethyl)Phenyl]-4-Methyl-3-[2-(Methylamino)Quinazolin-6-Yl]Benzamide Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.30 Å Release Date: 2015-01-28 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 3Z1, TLA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-01-28
Ligands: 3Z1, TLA
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Co-Crystal Structure Of Perk Bound To 4-{2-Amino-3-[5-Fluoro-2-(Methylamino)Quinazolin-6-Yl]-4-Methylbenzoyl}-1-Methyl-2,5-Diphenyl-1,2-Dihydro-3H-Pyrazol-3-One Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.80 Å Release Date: 2015-01-28 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 3Z3, TLA, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-01-28
Ligands: 3Z3, TLA, GOL
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Co-Crystal Structure Of Perk Bound To 4-{2-Amino-4-Methyl-3-[2-(Methylamino)-1,3-Benzothiazol-6-Yl]Benzoyl}-1-Methyl-2,5-Diphenyl-1,2-Dihydro-3H-Pyrazol-3-One Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.90 Å Release Date: 2015-01-28 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 3Z4, TLA, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-01-28
Ligands: 3Z4, TLA, GOL
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Co-Crystal Structure Of Perk Bound To 4-[2-Amino-4-Methyl-3-(2-Methylquinolin-6-Yl)Benzoyl]-1-Methyl-2,5-Diphenyl-1,2-Dihydro-3H-Pyrazol-3-One Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.35 Å Release Date: 2015-01-28 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 3Z5, TLA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-01-28
Ligands: 3Z5, TLA
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Co-Crystal Structure Of Perk Bound To 1-[5-(4-Amino-2,7-Dimethyl-7H-Pyrrolo[2,3-D]Pyrimidin-5-Yl)-2,3-Dihydro-1H-Indol-1-Yl]-2-[3-Fluoro-5-(Trifluoromethyl)Phenyl]Ethanone Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.65 Å Release Date: 2015-01-28 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 3Z6 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-01-28
Ligands: 3Z6
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Human Gkrp Bound To Amg-2526 And S6P
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.80 Å Release Date: 2014-10-08 Classification: CARBOHYDRATE BINDING PROTEIN/INHIBITOR Ligands: 2TE, S6P, IOD, GOL, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-10-08
Ligands: 2TE, S6P, IOD, GOL, SO4
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Human Gkrp Bound To Amg-0771 And Sorbitol-6-Phosphate
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.40 Å Release Date: 2014-07-30 Classification: CARBOHYDRATE BINDING PROTEIN/INHIBITOR Ligands: 2TF, S6P, IOD, GOL, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-07-30
Ligands: 2TF, S6P, IOD, GOL, SO4
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Human Gkrp Bound To Amg-2668
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.58 Å Release Date: 2014-07-30 Classification: CARBOHYDRATE BINDING PROTEIN/INHIBITOR Ligands: 2TG, S6P, IOD, GOL, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-07-30
Ligands: 2TG, S6P, IOD, GOL, SO4
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Human Gkrp Bound To Amg-3227 And S6P
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.40 Å Release Date: 2014-07-30 Classification: CARBOHYDRATE BINDING PROTEIN/INHIBITOR Ligands: 2TJ, S6P, IOD, GOL, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-07-30
Ligands: 2TJ, S6P, IOD, GOL, SO4
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Gkrp Bound To Amg0556 And Sorbitol-6-Phosphate
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.39 Å Release Date: 2014-07-30 Classification: CARBOHYDRATE BINDING PROTEIN/INHIBITOR Ligands: 2UW, S6P, IOD, GOL, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-07-30
Ligands: 2UW, S6P, IOD, GOL, SO4
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Gkrp Bound To Amg-0471 And Sorbitol-6-Phosphate
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.24 Å Release Date: 2014-07-30 Classification: CARBOHYDRATE BINDING PROTEIN/INHIBITOR Ligands: 2UX, S6P, IOD, GOL, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-07-30
Ligands: 2UX, S6P, IOD, GOL, SO4
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Human Gkrp Bound To Amg-5112 And Sorbitol-6-Phosphate
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.82 Å Release Date: 2014-07-30 Classification: CARBOHYDRATE BINDING PROTEIN/INHIBITOR Ligands: 2UY, S6P, IOD, GOL, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-07-30
Ligands: 2UY, S6P, IOD, GOL, SO4
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Human Gkrp Bound To Amg5106 And Sorbitol-6-Phosphate
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.40 Å Release Date: 2014-07-23 Classification: CARBOHYDRATE BINDING PROTEIN Ligands: 2TO, S6P, IOD, GOL, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-07-23
Ligands: 2TO, S6P, IOD, GOL, SO4
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Human Gkrp Complexed To Amg-3969 And S6P
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.22 Å Release Date: 2014-05-07 Classification: Transferase Inhibitor Ligands: MG9, S6P, IOD, GOL, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-05-07
Ligands: MG9, S6P, IOD, GOL, SO4
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Human Gkrp Bound To Amg-5980 And S6P
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.20 Å Release Date: 2014-05-07 Classification: Transferase Inhibitor Ligands: MG0, S6P, IOD, GOL, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-05-07
Ligands: MG0, S6P, IOD, GOL, SO4
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Human Gkrp Complexed To Amg-1694 [(2R)-1,1,1-Trifluoro-2-{4-[(2S)-2-{[(3S)-3-Methylmorpholin-4-Yl]Methyl}-4-(Thiophen-2-Ylsulfonyl)Piperazin-1-Yl]Phenyl}Propan-2-Ol] And Sorbitol-6-Phosphate
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.35 Å Release Date: 2013-11-20 Classification: Carbohydrate Binding protein Ligands: IOD, S6P, 1YY, GOL, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-11-20
Ligands: IOD, S6P, 1YY, GOL, SO4