Search Count: 13
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Aminomethyl-Derived Beta Secretase (Bace1) Inhibitors: Engaging Gly230 Without An Anilide Functionality
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.78 Å Release Date: 2017-01-11 Classification: HYDROLASE/HYDROLASE inhibitor Ligands: P6U, IOD, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-01-11
Ligands: P6U, IOD, EDO
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Aminomethyl-Derived Beta Secretase (Bace1) Inhibitors: Engaging Gly230 Without An Anilide Functionality
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.96 Å Release Date: 2017-01-11 Classification: HYDROLASE/HYDROLASE inhibitor Ligands: 74B, IOD, NA, GOL, DMS, CL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-01-11
Ligands: 74B, IOD, NA, GOL, DMS, CL
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Structure Of Cytochrome P450 2D6 (Cyp2D6) Bace1 Inhibitor Complex
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.71 Å Release Date: 2017-01-11 Classification: OXIDOREDUCTASE/OXIDOREDUCTASE inhibitor Ligands: HEM, ZN, P6U |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-01-11
Ligands: HEM, ZN, P6U
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Structure Of Cytochrome P450 2D6 (Cyp2D6) Bace1 Inhibitor Complex
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.75 Å Release Date: 2017-01-11 Classification: OXIDOREDUCTASE/OXIDOREDUCTASE inhibitor Ligands: HEM, ZN, P6M |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-01-11
Ligands: HEM, ZN, P6M
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Crystal Structure Of Gsk-3Beta Complexed With Pf-04802367, A Highly Selective Brain-Penetrant Kinase Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.20 Å Release Date: 2016-09-21 Classification: TRANSFERASE Ligands: 6QH, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-09-21
Ligands: 6QH, SO4
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Human Cytochrome P450 2D6 Bace1 Inhibitor 5 Complex
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.50 Å Release Date: 2015-05-20 Classification: OXIDOREDUCTASE Ligands: HEM, SI5, ZN |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-05-20
Ligands: HEM, SI5, ZN
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Human Cytochrome P450 2D6 Bace1 Inhibitor 6 Complex
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.40 Å Release Date: 2015-05-20 Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR Ligands: HEM, SI6, ZN, GOL, NA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-05-20
Ligands: HEM, SI6, ZN, GOL, NA
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Crystal Structure Of Bace1 With A Pyrazole-Substituted Tetrahydropyran Thioamidine
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.86 Å Release Date: 2015-04-01 Classification: hydrolase/hydrolase inhibitor Ligands: SI5, IOD, GOL, DMS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-04-01
Ligands: SI5, IOD, GOL, DMS
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Crystal Structure Of Human Bace-1 Bound To Compound 24B
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.98 Å Release Date: 2015-03-04 Classification: Hydrolase/hydrolase inhibitor Ligands: 3VO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-03-04
Ligands: 3VO
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Crystal Structure Of Human Bace-1 Bound To Compound 36
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.10 Å Release Date: 2015-03-04 Classification: Hydrolase/hydrolase inhibitor Ligands: 3VP, IOD, DMS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-03-04
Ligands: 3VP, IOD, DMS
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Crystal Structure Of Human Bace-1 Bound To Compound 6
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.55 Å Release Date: 2015-03-04 Classification: Hydrolase/Hydrolase inhibitor Ligands: 3WP, IOD, NA, GOL, DMS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-03-04
Ligands: 3WP, IOD, NA, GOL, DMS
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Crystal Structure Of Bace With Compound 14G
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.56 Å Release Date: 2012-10-03 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: 0UP, ZN |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2012-10-03
Ligands: 0UP, ZN
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Crystal Structure Of Bace With Compound 12A
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.90 Å Release Date: 2012-10-03 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: 0UQ, ZN, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2012-10-03
Ligands: 0UQ, ZN, EDO